Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lydia Thelma Poluha"'
Autor:
Iole Ferrara-Romeo, Paula Martinez, Sarita Saraswati, Kurt Whittemore, Osvaldo Graña-Castro, Lydia Thelma Poluha, Rosa Serrano, Elena Hernandez-Encinas, Carmen Blanco-Aparicio, Juana Maria Flores, Maria A. Blasco
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Telomerase deficiency leads to age-related diseases and shortened lifespan, while inhibition of the mTOR pathway delays aging. Here, the authors show that inhibition of mTORC1 signaling shortens the lifespan of telomerase deficient mice.
Externí odkaz:
https://doaj.org/article/4d4074052eef403bb59da8eb2a97f7ad
Autor:
Maria A. Blasco, Carmen Blanco-Aparicio, Kurt Whittemore, Paula Martinez, Sarita Saraswati, Lydia Thelma Poluha, Iole Ferrara-Romeo, Osvaldo Graña-Castro, Juana M. Flores, Elena Hernández-Encinas, Rosa Serrano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)
Telomerase deficiency leads to age-related diseases and shorter lifespans. Inhibition of the mechanistic target of rapamycin (mTOR) delays aging and age-related pathologies. Here, we show that telomerase deficient mice with short telomeres (G2-Terc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d254c5dd1f990af89bfdc3ef466bc6bb
https://doaj.org/article/4d4074052eef403bb59da8eb2a97f7ad
https://doaj.org/article/4d4074052eef403bb59da8eb2a97f7ad