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Detection of a Recurrent DNAJB1-PRKACA Chimeric Transcript in Fibrolamellar Hepatocellular Carcinoma
Autor:
Vladimir Vacic, Sanford M. Simon, Constantin N. Takacs, David G. Darcy, Umesh Bhanot, Soren Germer, Caroline E. Gleason, Nicolas Robine, R.L. Belote, Anne-Katrin Emde, Sergio Botero, Elana P. Simon, Irene Isabel P. Lim, Jennifer M. Murphy, Rachel Chiaroni-Clarke, Brad R. Rosenberg, Michael P. LaQuaglia, Lydia Teegan, Joshua N. Honeyman
Publikováno v:
Science. 343:1010-1014
Oncogenic Suspect Exposed It can be difficult logistically to study the genomics of rare variants of common cancers. Nevertheless, Honeyman et al. (p. 1010 ) studied fibrolamellar hepatocellular carcinoma (FL-HCC), a rare and poorly understood liver