Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lydia T. Tam"'
Autor:
Peter K. Moon, Jason Z. Qian, Emily McKenna, Kevin Xi, Nathan C. Rowe, Nathan N. Ng, Jimmy Zheng, Lydia T. Tam, Sarah J. MacEachern, Iram Ahmad, Alan G. Cheng, Nils D. Forkert, Kristen W. Yeom
Publikováno v:
NeuroImage: Clinical, Vol 27, Iss , Pp 102328- (2020)
Purpose: Sensorineural hearing loss (SNHL) is the most prevalent congenital sensory deficit in children. Information regarding underlying brain microstructure could offer insight into neural development in deaf children and potentially guide therapie
Externí odkaz:
https://doaj.org/article/aab31760a353452ba4d75f000dbb47fc
Autor:
Michael Zhang, Samuel W. Wong, Jason N. Wright, Matthias W. Wagner, Sebastian Toescu, Michelle Han, Lydia T. Tam, Quan Zhou, Saman S. Ahmadian, Katie Shpanskaya, Seth Lummus, Hollie Lai, Azam Eghbal, Alireza Radmanesh, Jordan Nemelka, Stephen Harward, Michael Malinzak, Suzanne Laughlin, Sébastien Perreault, Kristina R. M. Braun, Robert M. Lober, Yoon Jae Cho, Birgit Ertl-Wagner, Chang Y. Ho, Kshitij Mankad, Hannes Vogel, Samuel H. Cheshier, Thomas S. Jacques, Kristian Aquilina, Paul G. Fisher, Michael Taylor, Tina Poussaint, Nicholas A. Vitanza, Gerald A. Grant, Stefan Pfister, Eric Thompson, Alok Jaju, Vijay Ramaswamy, Kristen W. Yeom
Publikováno v:
Radiology. 304:406-416
Background Radiogenomics of pediatric medulloblastoma (MB) offers an opportunity for MB risk stratification, which may aid therapeutic decision making, family counseling, and selection of patient groups suitable for targeted genetic analysis. Purpose
Autor:
Juliet K. Knowles, Haojun Xu, Caroline Soane, Ankita Batra, Tristan Saucedo, Eleanor Frost, Lydia T. Tam, Danielle Fraga, Lijun Ni, Katlin Villar, Sydney Talmi, John R. Huguenard, Michelle Monje
Publikováno v:
Nature Neuroscience. 25:596-606
Activity-dependent myelination can fine-tune neural network dynamics. Conversely, aberrant neuronal activity, as occurs in disorders of recurrent seizures (epilepsy), could promote maladaptive myelination, contributing to pathogenesis. In this study,
Autor:
Gerald A. Grant, Michael Zhang, Alireza Radmanesh, Thomas S. Jacques, Ozgur Oztekin, Samuel H. Cheshier, Stefan M. Pfister, Chang Y Ho, Robert Lober, Kristen W. Yeom, Edward Wang, Lydia T. Tam, Kshitij Mankad, Michael D. Taylor, Eric Chen, Jason N. Wright, Sarah A. Mattonen, Birgit Ertl-Wagner, Vijay Ramaswamy, Jordan Nemelka, Kristian Aquilina, Nicholas A Vitanza, Paul G. Fisher, Mourad Said, Emre Altinmakas, Alok Jaju, Derek Yecies, Sebastian Toescu, Michelle Han, Matthias W Wagner
Publikováno v:
Neuro-Oncology. 24:986-994
Background The risk profile for posterior fossa ependymoma (EP) depends on surgical and molecular status [Group A (PFA) versus Group B (PFB)]. While subtotal tumor resection is known to confer worse prognosis, MRI-based EP risk-profiling is unexplore
Autor:
Sandy Napel, Brandon W. Smith, Lydia T. Tam, Edward H. Lee, Robert J. Spinner, Forrest Hamrick, Kristen W. Yeom, Jayne Seekins, Thomas J. Wilson, Courtney Pendleton, Sarah A. Mattonen, Cynthia J. Campen, Nicholas F Hug, Sandip Biswal, Mark A. Mahan, Michael Zhang, Elizabeth Tong
Publikováno v:
Neurosurgery
Background Clinicoradiologic differentiation between benign and malignant peripheral nerve sheath tumors (PNSTs) has important management implications. Objective To develop and evaluate machine-learning approaches to differentiate benign from maligna
Autor:
Hannes Vogel, Shawn M. Gillespie, Anna Geraghty, Dana Silverbush, Dwight E. Bergles, Lydia T. Tam, David Brang, Pamelyn Woo, Anitha Ponnuswami, Cedric Espenel, Kathryn R. Taylor, Lijun Ni, Mario L. Suvà, Marlene Arzt, Amit Agarwal, Shawn L. Hervey-Jumper, Robert C. Malenka, Aviv Regev, Humsa S. Venkatesh, Wade Morishita, Michelle Monje
Publikováno v:
Nature. 573:539-545
High-grade gliomas are lethal brain cancers whose progression is robustly regulated by neuronal activity. Activity-regulated release of growth factors promotes glioma growth, but this alone is insufficient to explain the effect that neuronal activity
Autor:
Hollie Lai, Sarah A. Mattonen, Ozgur Oztekin, Alok Jaju, Samuel H. Cheshier, Sandy Napel, Robert M. Lober, C.Y. Ho, Alireza Radmanesh, Sebastian Toescu, Mourad Said, Thomas S. Jacques, Michelle Han, Jason N. Wright, Lydia T. Tam, Kristian Aquilina, Eric Chen, Andrew Campion, Azam A Eghbal, Nicholas A Vitanza, Darren Hargrave, Kristen W. Yeom, Kshitij Mankad, Michelle Monje, Maryam Maleki, Robert Goetti
Publikováno v:
Neuro-oncology Advances
Background Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors. Presently, MRI is the mainstay of disease diagnosis and surveillance. We identify clinically significant computational features from MRI and create a prognostic m
Autor:
Gerald A. Grant, Michelle Han, Rashad Jabarkheel, Darren Hargrave, Kristen W. Yeom, Kristian Aquilina, Thomas S. Jacques, Lydia T. Tam, Kshitij Mankad, Vijay Ramaswamy, Robert M. Lober, Samuel H. Cheshier, Derek Yecies, Nick Vitanza, Michael D. Taylor
Publikováno v:
Neurosurgery. 67
Autor:
Lijun Ni, Danielle A. Fraga, Juliet K. Knowles, Michelle Monje, Caroline Soane, Eleanor Frost, Ankita Batra, Katlin Villar, Lydia T. Tam, Tristan Saucedo, John R. Huguenard, Haojun Xu
SummaryNeuronal activity can influence the generation of new oligodendrocytes (oligodendrogenesis) and myelination. In health, this is an adaptive process that can increase synchrony within distributed neuronal networks and contribute to cognitive fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f0a2b96091fdd0bae6a4986216dfa4
https://doi.org/10.1101/2020.08.20.260083
https://doi.org/10.1101/2020.08.20.260083
Autor:
Peter K. Moon, Margo Thienemann, Emily McKenna, Jimmy Zheng, Nils D. Forkert, Jennifer Frankovich, Jaynelle Gao, Kristen W. Yeom, Sarah J. MacEachern, Nathan C. Rowe, Nathan Ng, Lydia T. Tam
Publikováno v:
JAMA Network Open
This case-control study investigates whether diffusion-weighted imaging shows microstructural abnormalities across the brain regions of children with pediatric acute-onset neuropsychiatric syndrome.
Key Points Question How does diffusion-weighte
Key Points Question How does diffusion-weighte