Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Lydia Reinhardt"'
Autor:
Lamiaa Bahnassawy, Nathalie Nicolaisen, Christopher Untucht, Benjamin Mielich-Süss, Lydia Reinhardt, Janina S. Ried, Martina P. Morawe, Daniela Geist, Anja Finck, Elke Käfer, Jürgen Korffmann, Matthew Townsend, Brinda Ravikumar, Viktor Lakics, Miroslav Cik, Peter Reinhardt
Publikováno v:
SLAS Discovery, Vol 29, Iss 2, Pp 100137- (2024)
Aberrant protein aggregation is a pathological cellular hallmark of many neurodegenerative diseases, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD), where the tau protein is aggregating, forming neurofibrillary tangles (NFTs), and
Externí odkaz:
https://doaj.org/article/88acc957513a468cbf3eadb12ef4e1e8
Autor:
Lydia Reinhardt, Cristin Strasser, Theresa Steeb, Anne Petzold, Markus V Heppt, Anja Wessely, Carola Berking, Friedegund Meier
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308508 (2024)
BackgroundIn Germany, skin cancer screening (SCS) is available free of charge every two years to all those with statutory health insurance over the age of 35. General Practitioners (GP) can carry out the screening if they have completed an 8-hour tra
Externí odkaz:
https://doaj.org/article/0f8bf982aa8848b3800013350c12ebb4
Autor:
Lydia Reinhardt, Fabrizio Musacchio, Maria Bichmann, Annika Behrendt, Ebru Ercan-Herbst, Juliane Stein, Isabelle Becher, Per Haberkant, Julia Mader, David C. Schöndorf, Melanie Schmitt, Jürgen Korffmann, Peter Reinhardt, Christian Pohl, Mikhail Savitski, Corinna Klein, Laura Gasparini, Martin Fuhrmann, Dagmar E. Ehrnhoefer
Publikováno v:
Neurobiology of Disease, Vol 182, Iss , Pp 106126- (2023)
Intraneuronal aggregates of the microtubule binding protein Tau are a hallmark of different neurodegenerative diseases including Alzheimer's disease (AD). In these aggregates, Tau is modified by posttranslational modifications such as phosphorylation
Externí odkaz:
https://doaj.org/article/ff39934c4d48495f9ed3afb8322255d0
Autor:
Priyanka Bhatia, Marc Bickle, Amay A. Agrawal, Buster Truss, Aikaterina Nikolaidi, Kathrin Brockmann, Lydia Reinhardt, Stefanie Vogel, Eva M. Szegoe, Arun Pal, Andreas Hermann, Ivan Mikicic, Maximina Yun, Björn Falkenburger, Jared Sterneckert
Publikováno v:
Biology, Vol 13, Iss 1, p 58 (2024)
The degeneration of axon terminals before the soma, referred to as “dying back”, is a feature of Parkinson’s disease (PD). Axonal assays are needed to model early PD pathogenesis as well as identify protective therapeutics. We hypothesized that
Externí odkaz:
https://doaj.org/article/4952ffb943c34abcbcc6ad2a203b9ec1
Autor:
Josephine Mathiebe, Lydia Reinhardt, Maike Bergmann, Marina Lindauer, Alina Herrmann, Cristin Strasser, Friedegund Meier, Jochen Schmitt
Publikováno v:
Current Oncology, Vol 29, Iss 4, Pp 2583-2598 (2022)
Skin cancer is one of the most common cancers worldwide and the number of patients is steadily increasing. In skin cancer care, greater interdisciplinary cooperation is required for prevention, early detection, and new complex systemic therapies. How
Externí odkaz:
https://doaj.org/article/5cdaa7f72c84477ba9939d33cce89d6e
Autor:
Svenja Vanessa Wiedemann, Verena Müller, Bettina Toth, Michael Erdmann, Bodo Bühler, Susanne Dugas-Breit, Kerstin Schatton, Lydia Reinhardt, Markus Meissner, Marion Mickler, Claudia Pföhler, Carsten Weishaupt, Rudolf Herbst, Dirk Debus, Laura Susok, Julia Katharina Tietze, Julia Welzel, Andreas Arnold, Evelyn Dabrowski, Andrea Forschner, Steven Goetze, Kinan Hayani, Céleste Lebbe, Florian Löhr, Miriam Mengoni, Barbara Hermes, Wiebke Katharina Peitsch, Gabriela Poch, Michael Max Sachse, Anca Sindrilaru, Saskia Wenk, Mirjana Ziemer, Kjell Kaune, Lisette Meier-Naust, Georgios Nikolakis, Florian Oberndörfer, Ulrich Wesselmann, Jochen Sven Utikal, Maria Rita Gaiser
Publikováno v:
EJC Skin Cancer, Vol 1, Iss , Pp 100005- (2023)
Background: Vertical transmission of maternal cancer cells to the child is extremely rare, but melanoma represents the most common culprit. The aim of this study is to determine individual risks for materno-fetal transmission of melanoma cells and to
Externí odkaz:
https://doaj.org/article/4036126cff80416c9021fb86c201d9e0
Autor:
Leonie Müller-Jensen, Sarah Zierold, Judith M Versluis, Wolfgang Boehmerle, Petra Huehnchen, Matthias Endres, Raphael Mohr, Annette Compter, Christian U Blank, Tim Hagenacker, Friedegund Meier, Lydia Reinhardt, Anja Gesierich, Martin Salzmann, Jessica C Hassel, Selma Ugurel, Lisa Zimmer, Patricia Banks, Lavinia Spain, Jennifer A Soon, Tomohiro Enokida, Makoto Tahara, Katharina C Kähler, Ruth Seggewiss-Bernhardt, Catriona Harvey, Georgina V Long, Florian Schöberl, Louisa von Baumgarten, Thomas Hundsberger, Max Schlaak, Lars E French, Samuel Knauss, Lucie M Heinzerling
Publikováno v:
Data in Brief, Vol 45, Iss , Pp 108649- (2022)
Over the past decade, cancer immunotherapy with immune checkpoint inhibitors (ICIs) has significantly improved the outcome of many malignancies. However, with the broad use of ICIs, neurological immune related adverse events (irAE) are increasingly r
Externí odkaz:
https://doaj.org/article/c91a9542a832459593f5a6f29e793e54
Autor:
Theresa Steeb, Lydia Reinhardt, Matthias Harlaß, Markus Vincent Heppt, Friedegund Meier, Carola Berking
Publikováno v:
JMIR Cancer, Vol 8, Iss 1, p e29581 (2022)
BackgroundPatients with skin cancer increasingly watch online videos to acquire disease-related information. Until now, no scientific evaluation of the quality of videos available for German-speaking patients with basal cell carcinoma (BCC) has been
Externí odkaz:
https://doaj.org/article/a22f97657ebf455a9a98eaf9fbcbfb72
Autor:
Anne Zaremba, Rafaela Kramer, Viola De Temple, Stefanie Bertram, Martin Salzmann, Anja Gesierich, Lydia Reinhardt, Barouyr Baroudjian, Michael M. Sachse, Gunhild Mechtersheimer, Douglas B. Johnson, Alison M. Weppler, Lavinia Spain, Carmen Loquai, Milena Dudda, Claudia Pföhler, Adriana Hepner, Georgina V. Long, Alexander M. Menzies, Matteo S. Carlino, Céleste Lebbé, Tomohiro Enokida, Makoto Tahara, Paul J. Bröckelmann, Thomas Eigentler, Katharina C. Kähler, Ralf Gutzmer, Carola Berking, Selma Ugurel, Nadine Stadtler, Antje Sucker, Jürgen C. Becker, Elisabeth Livingstone, Friedegund Meier, Jessica C. Hassel, Dirk Schadendorf, Maher Hanoun, Lucie Heinzerling, Lisa Zimmer
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
IntroductionImmune checkpoint inhibitors (ICI) are increasingly being used to treat numerous cancer types. Together with improved recognition of toxicities, this has led to more frequent identification of rare immune-related adverse events (irAE), fo
Externí odkaz:
https://doaj.org/article/d10a83d504ce49babdcbd1b891ef629b
Autor:
Markus V. Heppt, Teresa Amaral, Katharina C. Kähler, Lucie Heinzerling, Jessica C. Hassel, Markus Meissner, Nicole Kreuzberg, Carmen Loquai, Lydia Reinhardt, Jochen Utikal, Evelyn Dabrowski, Anja Gesierich, Claudia Pföhler, Patrick Terheyden, Kai-Martin Thoms, Lisa Zimmer, Thomas K. Eigentler, Michael C. Kirchberger, Henner M. Stege, Friedegund Meier, Max Schlaak, Carola Berking
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Uveal melanoma (UM) is highly refractory to treatment with dismal prognosis in advanced stages. The value of the combined checkpoint blockade with CTLA-4 and PD-1 inhibition in metastatic UM is currently unclear. Methods Patients
Externí odkaz:
https://doaj.org/article/39e18ef3acc940829b41d0958141f699