Výsledky vyhledávání - "Lydia M Emerson"

Akademický článek

Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial

Autor: Bronagh Blackwood, Matt P Wise, Kalliopi Kydonaki, Nazir I Lone, Timothy S Walsh, Christopher J Weir, Benedict Creagh-Brown, Michael C Reade, Lydia M Emerson, Leanne M Aitken, Cathrine A McKenzie

Publikováno v: BMJ Open, Vol 14, Iss 4 (2024)

Introduction An association between deep sedation and adverse short-term outcomes has been demonstrated although this evidence has been inconsistent. The A2B (alpha-2 agonists for sedation in critical care) sedation trial is designed to determine whe

Externí odkaz: https://doaj.org/article/7a01bb1c8b5844ff8bd2b7e8e36df0b2

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Akademický článek

A nurse-led, preventive, psychological intervention to reduce PTSD symptom severity in critically ill patients: the POPPI feasibility study and cluster RCT

Autor: Paul R Mouncey, Dorothy Wade, Alvin Richards-Belle, Zia Sadique, Jerome Wulff, Richard Grieve, Lydia M Emerson, Chris R Brewin, Sheila Harvey, David Howell, Nicholas Hudson, Imran Khan, Monty Mythen, Deborah Smyth, John Weinman, John Welch, David A Harrison, Kathryn M Rowan

Publikováno v: Health Services and Delivery Research, Vol 7, Iss 30 (2019)

Background: High numbers of patients experience severe acute stress in critical care units. Acute stress has been linked to post-critical care psychological morbidity, including post-traumatic stress disorder (PTSD). Previously, a preventive, complex

Externí odkaz: https://doaj.org/article/13f3a40c40b44a80abc9fe6e731f4361

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Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial

Autor: Jonathan A. Silversides, Ross McMullan, Lydia M. Emerson, Ian Bradbury, Jonathan Bannard-Smith, Tamas Szakmany, John Trinder, Anthony J. Rostron, Paul Johnston, Andrew J. Ferguson, Andrew J. Boyle, Bronagh Blackwood, John C. Marshall, Daniel F. McAuley

Publikováno v: Silversides, J A, McMullan, R, Emerson, L M, Bradbury, I, Bannard-Smith, J, Szakmany, T, Trinder, T J, Rostron, A J, Johnston, P, Ferguson, A J, Boyle, A J, Blackwood, B, Marshall, J C & McAuley, D F 2021, ' Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial ', Intensive Care Medicine . https://doi.org/10.1007/s00134-021-06596-8

PURPOSE: Fluid overload is common in critical illness and is associated with mortality. This study investigated the feasibility of a randomised trial comparing conservative fluid administration and deresuscitation (active removal of accumulated fluid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8b962da27751b4579f09f44f4ecbbe
https://doi.org/10.1007/s00134-021-06596-8

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A nurse-led, preventive, psychological intervention to reduce PTSD symptom severity in critically ill patients: the POPPI feasibility study and cluster RCT

Autor: Lydia M Emerson, Jerome Wulff, Dorothy Wade, Monty G. Mythen, David A Harrison, John Weinman, Zia Sadique, Deborah Smyth, Alvin Richards-Belle, Sheila Harvey, Paul R Mouncey, Richard Grieve, Imran Khan, Chris R. Brewin, John Welch, Nicholas Hudson, David C. J. Howell, Kathryn M Rowan

Publikováno v: Health Services and Delivery Research, Vol 7, Iss 30 (2019)
Mouncey, P R, Wade, D M, Richards-Belle, A, Sadique, Z, Wulff, J, Grieve, R, Emerson, L, Brewin, C R, Harvey, S, Howell, D, Hudson, N, Khan, I, Mythen, M, Smyth, D, Weinman, J, Welch, J J, Harrison, D & Rowan, K M 2019, ' A nurse-led, preventive, psychological intervention to reduce PTSD symptom severity in critically ill patients: the POPPI feasibility study and cluster RCT ', Health Services and Delivery Research, vol. 7, no. 30 . https://doi.org/10.3310/hsdr07300

Background High numbers of patients experience severe acute stress in critical care units. Acute stress has been linked to post-critical care psychological morbidity, including post-traumatic stress disorder (PTSD). Previously, a preventive, complex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6dd4b710b48dabe4002f40003c9fd84
https://doi.org/10.3310/hsdr07300

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More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia

Publikováno v: Hellyer, T P, McAuley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, D W J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia ', Annals of Translational Medicine, vol. 8, no. 13, pp. 840 . https://doi.org/10.21037/atm-20-3701
Ann Transl Med
ANNALS OF TRANSLATIONAL MEDICINE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f0c723a63b6a59126a0f7be7f8a2cf
https://pure.qub.ac.uk/en/publications/more-research-is-required-to-understand-factors-influencing-antibiotic-prescribing-in-complex-conditions-like-suspected-ventilatorassociated-pneumonia(564316aa-c89d-4960-b344-374989c640ea).html

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Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation

Publikováno v: LANCET RESPIRATORY MEDICINE
Hellyer, T P, Mcauley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, Mcmullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, D J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine . https://doi.org/10.1016/S2213-2600(19)30367-4
Ann Transl Med
Hellyer, T P, McAuley, D, Walsh, T S, Anderson, N H, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C, Baudouin, S V, Paterson, R W, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N, Welters, I, Bassford, C, Yates, B, Spencer, C, Laha, S, Hulme, J, Bonner, S, Linnett, V C, Sonksen, J, van den Broeck, T, Boschman, G, Keenan, J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2019, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine, vol. 8, no. 2, pp. 182 . https://doi.org/10.1016/S2213-2600(19)30367-4
Hellyer, T P, McAuley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, DW J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine, vol. 8, no. 2, pp. 182-191 . https://doi.org/10.1016/S2213-2600(19)30367-4

Background: Ventilator-associated pneumonia is the most common intensive care unit (ICU)-acquired infection, yet accurate diagnosis remains difficult, leading to overuse of antibiotics. Low concentrations of IL-1β and IL-8 in bronchoalveolar lavage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0819679fdb81603ef968776dfb2fb3b4
http://hdl.handle.net/10044/1/82700

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Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder Among Critically Ill Patients: A Randomized Clinical Trial

Publikováno v: Wade, D M, Mouncey, P R, Richards-Belle, A, Wulff, J, Harrison, D A, Sadique, M Z, Grieve, R D, Emerson, L M, Mason, A J, Aaronovitch, D, Als, N, Brewin, C R, Harvey, S E, Howell, D C J, Hudson, N, Mythen, M G, Smyth, D, Weinman, J, Welch, J, Whitman, C & Rowan, K M 2019, ' Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder among Critically Ill Patients : A Randomized Clinical Trial ', JAMA-Journal of the American Medical Association, vol. 321, no. 7, pp. 665-675 . https://doi.org/10.1001/jama.2019.0073
POPPI Trial Investigators 2019, ' Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder Among Critically Ill Patients: A Randomized Clinical Trial ', JAMA : the journal of the American Medical Association, vol. 321, no. 7, pp. 665-675 . https://doi.org/10.1001/jama.2019.0073

Importance: A meta-analysis of outcomes during the 6 months after intensive care unit (ICU) discharge indicate a prevalence for clinically important posttraumatic stress disorder (PTSD) symptoms of 25%. Objective: To determine whether a nurse-led pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19163931ee606611fa1f6526397c4555
https://pubmed.ncbi.nlm.nih.gov/30776299

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Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI) :Protocol for a cluster-randomised clinical trial of a complex intervention

Autor: Richard Grieve, Chris R. Brewin, David C. J. Howell, Kathryn M Rowan, David A Harrison, Dorothy Wade, Monty G. Mythen, Alvin Richards-Belle, Sheila Harvey, Paul R Mouncey, John Welch, John Weinman, Deborah Smyth, Lydia M Emerson, Zia Sadique

Publikováno v: Richards-Belle, A, Mouncey, P R, Wade, D, Brewin, C R, Emerson, L M, Grieve, R, Harrison, D A, Harvey, S, Howell, D, Mythen, M, Sadique, Z, Smyth, D, Weinman, J, Welch, J, Rowan, K M & POPPI Trial Investigators 2018, ' Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI) :Protocol for a cluster-randomised clinical trial of a complex intervention ', BMJ Open, vol. 8, no. 2, pp. e020908 . https://doi.org/10.1136/bmjopen-2017-020908
BMJ Open

IntroductionAcute psychological stress, as well as unusual experiences including hallucinations and delusions, are common in critical care unit patients and have been linked to post-critical care psychological morbidity such as post-traumatic stress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460db479e41fc5bfdc7defe6dfdc15c3
https://pure.qub.ac.uk/en/publications/psychological-outcomes-following-a-nurseled-preventative-psychological-intervention-for-critically-ill-patients-poppi-protocol-for-a-clusterrandomised-clinical-trial-of-a-complex-intervention(3a0ea378-c5e3-44b1-ae7f-33efc8bf9e92).html

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Erratum to::'Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial'

Autor: Thomas P. Hellyer, Niall H. Anderson, Jennie Parker, Paul Dark, Tina Van Den Broeck, Suveer Singh, Ronan McMullan, Ashley M. Agus, Lydia M. Emerson, Bronagh Blackwood, Savita Gossain, Tim S. Walsh, Gavin D. Perkins, Andrew Conway Morris, Daniel F. McAuley, A. John Simpson

Publikováno v: Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Morris, A C, McAuley, D F & Simpson, A J 2016, ' Erratum to: 'Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial' ', Trials, vol. 17, no. 1, 465, pp. 1 . https://doi.org/10.1186/s13063-016-1594-8
Trials

Background Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ffdec3e180ea0756b4440785f79dc5
https://doi.org/10.1186/s13063-016-1594-8

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Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial

Autor: Suveer Singh, Jennie Parker, Niall Anderson, Ashley Agus, Timothy S. Walsh, Gavin D. Perkins, Savita Gossain, Andrew Conway Morris, Lydia M Emerson, A. John Simpson, Thomas P Hellyer, Paul Dark, Tina Van Den Broeck, Bronagh Blackwood, Ronan McMullan, Daniel F. McAuley

Publikováno v: Trials
Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Conway Morris, A, McAuley, D F & Simpson, A J 2016, ' Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2) : Study protocol for a randomised controlled trial ', Trials, vol. 17, no. 1, 318, pp. 318 . https://doi.org/10.1186/s13063-016-1442-x, https://doi.org/10.1186/s13063-016-1442-x
Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Conway Morris, A, McAuley, D F & Simpson, A J 2016, ' Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2) : study protocol for a randomised controlled trial ', Trials, vol. 17, no. 1, pp. 318 . https://doi.org/10.1186/s13063-016-1442-x

Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage (BAL) fluid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63132763b2b644b00c5f0aa561b78b1e
https://doi.org/10.1186/s13063-016-1442-x

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