Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lydia Lutes"'
Autor:
Barbara U. Schraml, Christoph Scheiermann, Coline Barnoud, Elisabeth Deindl, Sophia Martina Hergenhan, Johanna Salvermoser, Manuel Lasch, Stephan Holtkamp, Alba de Juan, Burak Kizil, Louise Ince, Jasmin Weber, Chien-Sin Chen, Chen Wang, Lydia Lutes, Dirk Baumjohann
Publikováno v:
The journal of experimental medicine, Vol. 218, No 8 (2021) P. e20202377
The Journal of Experimental Medicine
The Journal of Experimental Medicine
This study shows loss of sympathetic innervation to the popliteal lymph node to induce IFN-γ expression in CD8 T cells, causing expansion. This is rescued by β2 adrenergic receptor agonists, demonstrating the pro-inflammatory effect of loss of dire
Autor:
Nadia S, Kurd, Ashley, Hoover, Jaewon, Yoon, Brian M, Weist, Lydia, Lutes, Shiao Wei, Chan, Ellen A, Robey
Publikováno v:
Mucosal immunology. 14(1)
Thymocytes bearing αβ T cell receptors (TCRαβ) with high affinity for self-peptide-MHC complexes undergo negative selection or are diverted to alternate T cell lineages, a process termed agonist selection. Among thymocytes bearing TCRs restricted
Publikováno v:
The Journal of Immunology. 204:61.13-61.13
T cells develop in the thymus where CD4+CD8+ double positive (DP) thymocytes undergo positive and negative selection to generate mature CD4+ and CD8+ single positive (SP) T cells. Positive selection allows for the generation of a diverse repertoire o