Reprogramming Intestinal Epithelial Cell Polarity by Interleukin-22

Autor: Deborah Delbue, Lydia Lebenheim, Danielle Cardoso-Silva, Violaine Dony, Susanne M. Krug, Jan F. Richter, Subhakankha Manna, Melba Muñoz, Kerstin Wolk, Claudia Heldt, Markus M. Heimesaat, Robert Sabat, Britta Siegmund, Michael Schumann

Publikováno v: Frontiers in Medicine, Vol 8 (2021)

Background: Interleukin-22 (IL-22) impacts the integrity of intestinal epithelia and has been associated with the development of colitis-associated cancer and inflammatory bowel diseases (IBD). Previous data suggest that IL-22 protects the mucosal ba

Externí odkaz: https://doaj.org/article/113c05147356492e9a76707d9906f783

A Novel Giant Non-Cholinergic Striatal Interneuron Restricted to the Ventrolateral Striatum Coexpresses Kv3.3 Potassium Channel, Parvalbumin, and the Vesicular GABA Transporter

Autor: Daniel S. Zahm, Lydia Lebenheim, Sam A. Booker, Rüdiger W. Veh, Imre Vida, Torsten Weiss, Franziska Wagner, Clemens Gruber, Christian Derst

Publikováno v: Lebenheim, L, Booker, S, Derst, C, Weiss, T, Wagner, F, Gruber, C, Vida, I, Zahm, D S & Veh, R W 2020, ' A Novel Giant Non-Cholinergic Striatal Interneuron Restricted to the Ventrolateral Striatum Coexpresses Kv3.3 Potassium Channel, Parvalbumin, and the Vesicular GABA Transporter ', Molecular Psychiatry, vol. N/A, pp. 1-14 . https://doi.org/10.1038/s41380-020-00948-4

The striatum is the main input structure of the basal ganglia. Distinct striatal subfields are involved in voluntary movement generation and cognitive and emotional tasks, but little is known about the morphological and molecular differences of stria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc614e5aeb04a9416ae3af8247f8ab91
https://www.pure.ed.ac.uk/ws/files/186571951/s41380_020_00948_4.pdf

Inflammatory myopathy with abundant macrophages (IMAM): The immunology revisited

Autor: Lydia Lebenheim, Hans-Hilmar Goebel, Verena Moos, Corinna Preuße, Michael Schumann, Werner Stenzel, Thomas Schneider, Frank L. Heppner, Jan Leo Rinnenthal

Publikováno v: Neuromuscular Disorders. 24:151-155

We describe a patient with a clinically atypical presentation of inflammatory myopathy with abundant macrophages (IMAM) but with convincing muscle biopsy features of this subform of inflammatory myopathy. IMAM is characterized mainly by a conspicuous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c2602ba799d3b639ccc10218827c7a
https://doi.org/10.1016/j.nmd.2013.11.004

[Celiac disease]

Autor: Michael, Schumann, Lydia, Lebenheim

Publikováno v: Deutsche medizinische Wochenschrift (1946). 141(20)

Celiac disease occurs as a result of a T-cell-dependent immune reaction on gluten peptides. It is a complex genetic disorder that is mediated by an unknown number of genes, of which more than 50 have been identified in whole genome association studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::77a3c7d3e30842dc56d2101fb8ad2b42
https://pubmed.ncbi.nlm.nih.gov/27701694

P101 Interleukin-13 induces polarity defects in the intestinal epithelia

Autor: Lydia Lebenheim, Michael Schumann, Nina A. Hering, Christian Bojarski, Britta Siegmund, A. Kühnel, Joerg-Dieter Schulzke

Publikováno v: Journal of Crohn's and Colitis. 11:S127-S128

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f17d1f9da61cecb28381876618ec604
https://doi.org/10.1093/ecco-jcc/jjx002.227