Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Lydia L. Sohn"'
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103772- (2022)
Summary: All-trans retinoic acid (ATRA) is an essential therapy in the treatment of acute promyelocytic leukemia (APL), but nearly 20% of patients with APL are resistant to ATRA. As there are no biomarkers for ATRA resistance that yet exist, we inves
Externí odkaz:
https://doaj.org/article/2841ba555add4e0091d595e04d74d677
Publikováno v:
Advanced Science, Vol 8, Iss 23, Pp n/a-n/a (2021)
Abstract Lipid‐based nanoparticles have been applied extensively in drug delivery and vaccine strategies and are finding diverse applications in the coronavirus disease 2019 (COVID‐19) pandemic—from vaccine‐component encapsulation to modeling
Externí odkaz:
https://doaj.org/article/cb1ef0b9b35b412ea70fadd52627e166
Autor:
Stefan Hinz, Antigoni Manousopoulou, Masaru Miyano, Rosalyn W. Sayaman, Kristina Y. Aguilera, Michael E. Todhunter, Jennifer C. Lopez, Lydia L. Sohn, Leo D. Wang, Mark A. LaBarge
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103026- (2021)
Summary: Age is the major risk factor in most carcinomas, yet little is known about how proteomes change with age in any human epithelium. We present comprehensive proteomes comprised of >9,000 total proteins and >15,000 phosphopeptides from normal p
Externí odkaz:
https://doaj.org/article/e72f584687ea4298b6399b8a51b8f7ce
Publikováno v:
iScience, Vol 13, Iss , Pp 214-228 (2019)
Summary: Viscoelastic properties of cells provide valuable information regarding biological or clinically relevant cellular characteristics. Here, we introduce a new, electronic-based, microfluidic platform—visco-node-pore sensing (visco-NPS)—whi
Externí odkaz:
https://doaj.org/article/2df59cb643dc49afbff1f31ccc3e0859
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Cellular mechanical properties can reveal physiologically relevant characteristics in many cell types, and several groups have developed microfluidics-based platforms to perform high-throughput single-cell mechanical testing. However, prior work has
Externí odkaz:
https://doaj.org/article/b8c42ce1699a4e268ea1c04141cc337e
Autor:
Thomas R. Carey, Molly Kozminsky, Jennifer Hall, Valerie Vargas-Zapata, Kristina Geiger, Laurent Coscoy, Lydia L. Sohn
Publikováno v:
medRxiv
The COVID-19 pandemic has revealed how an emerging pathogen can cause a sudden and dramatic increase in demand for viral testing. Testing pooled samples could meet this demand; however, the sensitivity of reverse transcription quantitative polymerase
Publikováno v:
Journal of Visualized Experiments.
Cellular mechanical properties are involved in a wide variety of biological processes and diseases, ranging from stem cell differentiation to cancer metastasis. Conventional methods for measuring these properties, such as atomic force microscopy (AFM
Publikováno v:
ACS Appl Mater Interfaces
Antibodies provide the functional biospecificity that has enabled the development of sensors, diagnostic tools, and assays in both laboratory and clinical settings. However, as multimarker screening becomes increasingly necessary due to the heterogen
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2394
Node-Pore Sensing, NPS, is an extremely versatile and powerful technique for the analysis of cells and the detection of extracellular vesicles (EVs). NPS involves measuring the modulated current pulse caused by a cell transiting a microfluidic channe
Publikováno v:
Berkeley Scientific Journal, vol 26, iss 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8312b4f479f7158ef4bb8eca263538c8
https://escholarship.org/uc/item/4kb9p30h
https://escholarship.org/uc/item/4kb9p30h