Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lydia Kgosana"'
Autor:
Abdessamad Tahiri-Alaoui, Yuguang Zhao, Yashar Sadigh, James Popplestone, Lydia Kgosana, Lorraine P Smith, Venugopal Nair
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114466 (2014)
Poly(A) binding protein 1 (PABP1) plays a central role in mRNA translation and stability and is a target by many viruses in diverse manners. We report a novel viral translational control strategy involving the recruitment of PABP1 to the 5' leader in
Externí odkaz:
https://doaj.org/article/8c3d3692ce6345259b3919061fd8f5ce
Autor:
Yuguang Zhao, Hongtao Xu, Yongxiu Yao, Lorraine P Smith, Lydia Kgosana, James Green, Lawrence Petherbridge, Susan J Baigent, Venugopal Nair
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001305 (2011)
Notwithstanding the well-characterised roles of a number of oncogenes in neoplastic transformation, microRNAs (miRNAs) are increasingly implicated in several human cancers. Discovery of miRNAs in several oncogenic herpesviruses such as KSHV has furth
Externí odkaz:
https://doaj.org/article/03b6cd31cdcb4554a8e5f74d35ff6cf4
Publikováno v:
Mwangi, W N, Vasoya, D, Kgosana, L B, Watson, M & Nair, V 2017, ' Differentially-expressed genes during spontaneous lytic switch of Marek’s disease virus in lymphoblastoid cell lines determined by global gene expression profiling ', Journal of General Virology, vol. 98, no. 4, pp. 779-790 . https://doi.org/10.1099/jgv.0.000744
The Journal of General Virology
The Journal of General Virology
Marek’s disease virus (MDV), an alphaherpesvirus of poultry, causes Marek’s disease and is characterized by visceral CD4+TCRαβ+ T-cell lymphomas in susceptible hosts. Immortal cell lines harbouring the viral genome have been generated from ex v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255201fc9bd240b2aa0eeccbecb2a76b
https://www.pure.ed.ac.uk/ws/files/35767828/779_vir000744.pdf
https://www.pure.ed.ac.uk/ws/files/35767828/779_vir000744.pdf
Autor:
Lydia Kgosana, Deepali Vasoya, Venugopal Nair, Lorraine P. Smith, Michael Watson, Yulong Gao, Yongxiu Yao, Xiaomei Wang
Publikováno v:
Yao, Y, Vasoya, D, Kgosana, L, Smith, L P, Gao, Y, Wang, X, Watson, M & Nair, V 2017, ' Activation of gga-miR-155 by reticuloendotheliosis virus T strain and its contribution to transformation ', Journal of General Virology . https://doi.org/10.1099/jgv.0.000718
The Journal of General Virology
The Journal of General Virology
The v-rel oncoprotein encoded by reticuloendotheliosis virus T strain (Rev-T) is a member of the rel/NF-κB family of transcription factors capable of transformation of primary chicken spleen and bone marrow cells. Rapid transformation of avian haema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14059109b95ecdb8865fed42be490a74
https://www.pure.ed.ac.uk/ws/files/30312319/JGV_manuscript_revised_final.pdf
https://www.pure.ed.ac.uk/ws/files/30312319/JGV_manuscript_revised_final.pdf
Autor:
Venugopal Nair, Susan J. Baigent, Ahmed A. Gamawa, Lorraine P. Smith, Lydia Kgosana, Andrew F. Read
Publikováno v:
Avian Diseases. 57:440-447
To assess the effect of various vaccine strains on replication and shedding of virulent Marek's disease virus from experimentally infected chickens, quantitative PCR (q-PCR) methods were developed to accurately quantify viral DNA in infected chickens
Autor:
Lydia Kgosana, Lorraine P. Smith, Venugopal Nair, Lawrence Petherbridge, Abdessamad Tahiri-Alaoui
Publikováno v:
Avian Diseases. 57:387-394
In addition to tumors, Marek's disease (MD) virus (MDV) can induce a variety of syndromes linked to the central nervous system. In fact, early descriptions of MD suggested that it was a condition affecting mainly the nervous system. Cytokines and oth
Autor:
Venugopal Nair, Abdessamad Tahiri-Alaoui, Lawrence Petherbridge, Lydia Kgosana, Suzan Baigent, William James, Lorraine P. Smith, Luke S. Lambeth
In this study, we have identified an internal ribosome entry site (IRES) from the highly infectious herpesvirus Marek's disease virus (MDV). The IRES was mapped to the intercistronic region (ICR) of a bicistronic mRNA that we cloned from the MDV-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2217f91b71fb2f476adb036a46f68ab9
https://ora.ox.ac.uk/objects/uuid:fb2c0185-58a4-46f4-b6d1-ce346faa891b
https://ora.ox.ac.uk/objects/uuid:fb2c0185-58a4-46f4-b6d1-ce346faa891b
Autor:
Lydia Kgosana, Venugopal Nair, Susan J. Baigent, Martin J. Allday, Lorraine P. Smith, Andrew C. Brown
Publikováno v:
Journal of Virology. 83:11142-11151
Marek's disease virus (MDV) is a lymphotropic alphaherpesvirus that induces fatal rapid-onset T-cell lymphomas in chickens, its natural host. The MDV-encoded nuclear oncoprotein Meq is essential for lymphomagenesis and acts as a regulator of transcri
Autor:
Luke Blackwell, David A. Kennedy, Venugopal Nair, Stephen W. Walkden-Brown, Susan J. Baigent, Lydia Kgosana, Andrew F. Read, Lorraine P. Smith, Claire Powers
Publikováno v:
PLoS Biology, Vol 13, Iss 7, p e1002198 (2015)
PLoS Biology
PLoS Biology
There is little doubt evolution has played a major role in preventing the control of infectious disease through antibiotic and insecticide resistance, but recent theory suggests disease interventions such as vaccination may lead to evolution of more
Autor:
Lawrence Petherbridge, Hongtao Xu, Lydia Kgosana, Susan J. Baigent, Lorraine P. Smith, Yongxiu Yao, Yuguang Zhao, Venugopal Nair, James C. Green
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 2, p e1001305 (2011)
PLoS Pathogens, Vol 7, Iss 2, p e1001305 (2011)
Notwithstanding the well-characterised roles of a number of oncogenes in neoplastic transformation, microRNAs (miRNAs) are increasingly implicated in several human cancers. Discovery of miRNAs in several oncogenic herpesviruses such as KSHV has furth