Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lydia K Lutes"'
Autor:
Lydia K Lutes, Zoë Steier, Laura L McIntyre, Shraddha Pandey, James Kaminski, Ashley R Hoover, Silvia Ariotti, Aaron Streets, Nir Yosef, Ellen A Robey
Publikováno v:
eLife, Vol 10 (2021)
Functional tuning of T cells based on their degree of self-reactivity is established during positive selection in the thymus, although how positive selection differs for thymocytes with relatively low versus high self-reactivity is unclear. In additi
Externí odkaz:
https://doaj.org/article/7576a36ea73d437fbdb9d9b7a5263164
Autor:
Nadia S Kurd, Lydia K Lutes, Jaewon Yoon, Shiao Wei Chan, Ivan L Dzhagalov, Ashley R Hoover, Ellen A Robey
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/bc3820e00e334aba90074c133f0dfb98
Autor:
Nadia S Kurd, Lydia K Lutes, Jaewon Yoon, Shiao Wei Chan, Ivan L Dzhagalov, Ashley R Hoover, Ellen A Robey
Publikováno v:
eLife, Vol 8 (2019)
Autoreactive thymocytes are eliminated during negative selection in the thymus, a process important for establishing self-tolerance. Thymic phagocytes serve to remove dead thymocytes, but whether they play additional roles during negative selection r
Externí odkaz:
https://doaj.org/article/fffba24565fc4ed5a994274e6a024134
Autor:
Alexandra Tsitsiklis, Derek J. Bangs, Lydia K. Lutes, Shiao W. Chan, Kristina M. Geiger, Andrew J. Modzelewski, Lara Labarta-Bajo, Yang Wang, Elina I. Zuniga, Shaodong Dai, Ellen A. Robey
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The CD8+ T cell response to the intracellular parasite Toxoplasma gondii varies dramatically between mouse strains, resulting in stark differences in control of the parasite. Protection in BALB/c mice can be attributed to an unusually strong and prot
Externí odkaz:
https://doaj.org/article/4aa56ee319d5430d9240f09b8b10ac7c
Publikováno v:
T-Cell Development ISBN: 9781071627396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4193ffc4ca51230b8a0168d32f9666e0
https://doi.org/10.1007/978-1-0716-2740-2_14
https://doi.org/10.1007/978-1-0716-2740-2_14
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2580
T cell development occurs in the thymus and is coordinated temporally and spatially within the highly complex thymic microenvironment. Therefore, T cell selection and maturation events cannot be fully recapitulated using traditional two-dimensional t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4deacbcfb38c23e6c1bd07b8cae8e1cc
https://pubmed.ncbi.nlm.nih.gov/36374461
https://pubmed.ncbi.nlm.nih.gov/36374461
Autor:
Lydia K Lutes, Nadia S. Kurd, Shiao Wei Chan, Ashley R Hoover, Ellen A. Robey, Jaewon Yoon, Brian M. Weist
Publikováno v:
Mucosal Immunology. 14:68-79
Thymocytes bearing αβ T cell receptors (TCRαβ) with high affinity for self-peptide-MHC complexes undergo negative selection or are diverted to alternate T cell lineages, a process termed agonist selection. Among thymocytes bearing TCRs restricted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8461d1386604d8067a548abd8d0a01ce
https://doi.org/10.1038/s41385-020-0295-5
https://doi.org/10.1038/s41385-020-0295-5
Publikováno v:
Science immunology. 7(72)
The immune system is highly time-of-day dependent. Pioneering studies in the 1960s were the first to identify immune responses to be under a circadian control. Only in the last decade, however, have the molecular factors governing circadian immune rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5a94e5417c47aa8145a4826d211d3d
https://pubmed.ncbi.nlm.nih.gov/35658012
https://pubmed.ncbi.nlm.nih.gov/35658012
Autor:
Coline Barnoud, Louise M. Ince, Lydia K. Lutes, Robert Pick, Chen Wang, Stéphane Jemelin, Christoph Scheiermann
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f499d19fcd741e6dc490d8f677aacacc
https://doi.org/10.1096/fasebj.2022.36.s1.r2867
https://doi.org/10.1096/fasebj.2022.36.s1.r2867
Autor:
Zoë Steier, Dominik A. Aylard, Laura L. McIntyre, Isabel Baldwin, Esther Jeong Yoon Kim, Lydia K. Lutes, Can Ergen, Tse-Shun Huang, Ellen A. Robey, Nir Yosef, Aaron Streets
The development of CD4 and CD8 T cells in the thymus is critical to adaptive immunity and is widely studied as a model of lineage commitment. Recognition of self-MHCI/II by the T cell antigen receptor (TCR) determines the lineage choice, but how dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa339506c9441417d2d8d273cde85050
https://doi.org/10.1101/2021.07.12.452119
https://doi.org/10.1101/2021.07.12.452119