Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lydia Gutierrez-Gonzalez"'
Autor:
Lydia Gutierrez-Gonzalez, Patrick F. Chinnery, Paul J. Tadrous, Tariq G. Fellous, Mona El-Bahrawy, Stuart McDonald, Satyajit Bhattacharya, Robert W. Taylor, Julia Burkert, Lisa Mears, Laura C. Greaves, George Elia, Christopher P. Day, Malcolm R. Alison, Adam Humphries, Hemant M. Kocher, Nemantha M.W. De‐Alwis, Douglas M. Turnbull, Nicholas A. Wright, Shahriar Islam
Publikováno v:
Stem Cells. 27:1410-1420
Methods for lineage tracing of stem cell progeny in human tissues are currently not available. We describe a technique for detecting the expansion of a single cell's progeny that contain clonal mitochondrial DNA (mtDNA) mutations affecting the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9098325d64a221c6d52bce1bed50dc66
https://doi.org/10.1002/stem.67
https://doi.org/10.1002/stem.67
Autor:
Maesha Deheragoda, Stuart McDonald, Nicholas A. Wright, Janusz Jankowski, Arjun Shankar, Simon J. Leedham, Marco Novelli, Lydia Gutierrez-Gonzalez, George Elia, Douglass M. Turnbull, Charles Imber
Publikováno v:
The Journal of Pathology. 217:489-496
Little is known about the clonal structure or stem cell architecture of the human small intestinal crypt/villus unit, or how mutations spread and become fixed. Using mitochondrial DNA (mtDNA) mutations as a marker of clonal expansion of stem cell pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94e15040746bbba092bc0f574d5e8f9
https://doi.org/10.1002/path.2502
https://doi.org/10.1002/path.2502
Publikováno v:
Current Cancer Therapy Reviews. 4:168-177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88a8a981792f32e12db8dbbeeeaae488
https://doi.org/10.2174/157339408785294249
https://doi.org/10.2174/157339408785294249
Publikováno v:
Digestive and Liver Disease. 40:510-522
This review concentrates on one main aspect of cancerization in the oesophagus and stomach: principally, intestinal metaplasia. There are at least two other important pathways that lead to cancer and do not need such a morphological transformation. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a71eaa4e381b8d453b57d33b973eb40
https://doi.org/10.1016/j.dld.2008.02.029
https://doi.org/10.1016/j.dld.2008.02.029
Autor:
Nicholas A. Wright, Marco Novelli, Lydia Gutierrez–Gonzalez, Eiji Yamada, Manuel Rodriguez–Justo, David L. Stoker, Stuart McDonald, Alicia Green, Simon J. Leedham, Yuuki Kishi, Shigeki Bamba, Janusz Jankowski, I Mitchell, Sean L. Preston, Rebecca Harrison, Tania Ventayol Garcia, Trevor A. Graham
Publikováno v:
Gastroenterology. 140(4)
Background & Aims Studies of the clonal architecture of gastric glands with intestinal metaplasia are important in our understanding of the progression from metaplasia to dysplasia. It is not clear if dysplasias are derived from intestinal metaplasia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3ebf4118417d3bfdb2ecd98bcee33f
https://pubmed.ncbi.nlm.nih.gov/21223968
https://pubmed.ncbi.nlm.nih.gov/21223968
Autor:
Lydia, Gutierrez-Gonzalez, Maesha, Deheragoda, George, Elia, Simon J, Leedham, Arjun, Shankar, Charles, Imber, Janusz A, Jankowski, Douglass M, Turnbull, Marco, Novelli, Nicholas A, Wright, Stuart A C, McDonald
Publikováno v:
The Journal of pathology. 217(4)
Little is known about the clonal structure or stem cell architecture of the human small intestinal crypt/villus unit, or how mutations spread and become fixed. Using mitochondrial DNA (mtDNA) mutations as a marker of clonal expansion of stem cell pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dae1678753bcf4c0d9f53b7a1879cd14
https://pubmed.ncbi.nlm.nih.gov/19156773
https://pubmed.ncbi.nlm.nih.gov/19156773