Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lydia Farrell"'
Autor:
Jason S. Williams, Adam T. Higgins, Katie J. Stott, Carly Thomas, Lydia Farrell, Cleo S. Bonnet, Severina Peneva, Anna V. Derrick, Trevor Hay, Tianqi Wang, Claire Morgan, Sarah Dwyer, Joshua D’Ambrogio, Catherine Hogan, Matthew J. Smalley, Lee Parry, Paul Dyson
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background Bacterial cancer therapy was first trialled in patients at the end of the nineteenth century. More recently, tumour-targeting bacteria have been harnessed to deliver plasmid-expressed therapeutic interfering RNA to a range of soli
Externí odkaz:
https://doaj.org/article/8c3e84c87887414daa7d1ff63ddb1679
Autor:
Tony van der Weerden, Pierre Beukes, Cecile de Klein, Kathryn Hutchinson, Lydia Farrell, Tinke Stormink, Alvaro Romera, Dawn Dalley, Ross Monaghan, David Chapman, Kevin Macdonald, Robyn Dynes
Publikováno v:
Animals, Vol 8, Iss 12, p 234 (2018)
An important challenge facing the New Zealand (NZ) dairy industry is development of production systems that can maintain or increase production and profitability, while reducing impacts on receiving environments including water and air. Using researc
Externí odkaz:
https://doaj.org/article/b1777da38d6f43fb8b92d5d8f81bbd52
Autor:
Norman Shreeve, Mike Hollinshead, Hormas Ghadially, Lydia Farrell, Gillian M. Griffiths, Peter Parham, Francesco Colucci, Amir Horowitz, Olympe Chazara, Oisin Huhn, Martin A. Ivarsson, Andrew M. Sharkey, Jakob Theorell, Puran Chen, Ashley Moffett, Lucy Gardner, Jane C. Stinchcombe
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
During early pregnancy, decidual innate lymphoid cells (dILCs) interact with surrounding maternal cells and invading fetal extravillous trophoblasts (EVT). Here, using mass cytometry, we characterise five main dILC subsets: decidual NK cells (dNK)1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b72ad428b60b188fcd862e92e2cc98
Autor:
Olympe Chazara, Martin A. Ivarsson, Philippa R. Kennedy, Francesco Colucci, Lydia Farrell, Shiqiu Xiong, Ashley Moffett, Susan E. Hiby, Andrew M. Sharkey, Lucy Gardner
Publikováno v:
The Journal of Immunology Author Choice
During human pregnancy, fetal trophoblast cells invade the decidua and remodel maternal spiral arteries to establish adequate nutrition during gestation. Tissue NK cells in the decidua (dNK) express inhibitory NK receptors (iNKR) that recognize allog
Autor:
Benjamin D. Simons, Ashley Moffett, Hilary O. D. Critchley, Maria J Gomez, Lucy Gardner, Tereza Cindrova-Davies, Graham J. Burton, Jasmine Hughes, Jan J. Brosens, Margherita Y. Turco, Michael Hollinshead, Steven G.E. Marsh, Lydia Farrell, Bon-Kyoung Koo, Myriam Hemberger
Publikováno v:
Turco, M Y, Gardner, L, Hughes, J, Cindrova-Davies, T, Gomez, M J, Farrell, L, Hollinshead, M, Marsh, S G E, Brosens, J J, Critchley, H O, Simons, B D, Hemberger, M, Koo, B-K, Moffett, A & Burton, G J 2017, ' Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium ', Nature Cell Biology, vol. 19, no. 5, pp. 568-577 . https://doi.org/10.1038/ncb3516
Nature cell biology
Nature cell biology
In humans, the endometrium, the uterine mucosal lining, undergoes dynamic changes throughout the menstrual cycle and pregnancy. Despite the importance of the endometrium as the site of implantation and nutritional support for the conceptus, there are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc16c5d60eaece56828d4e39a46c1c2
https://www.repository.cam.ac.uk/handle/1810/264553
https://www.repository.cam.ac.uk/handle/1810/264553
Autor:
Yassen, Abbas, Carolin Melati, Oefner, William J, Polacheck, Lucy, Gardner, Lydia, Farrell, Andrew, Sharkey, Roger, Kamm, Ashley, Moffett, Michelle L, Oyen
Publikováno v:
Journal of the Royal Society Interface
Pre-eclampsia, fetal growth restriction and stillbirth are major pregnancy disorders throughout the world. The underlying pathogenesis of these diseases is defective placentation characterized by inadequate invasion of extravillous placental trophobl
Autor:
Lydia Farrell, Maziar Ashrafian-Bonab, Richard M. Single, Francois Balloux, Susan E. Hiby, Mary Carrington, Ashley Moffett
Publikováno v:
Immunogenetics
Killer cell immunoglobulin-like receptors (KIR) gene frequencies vary between populations and contribute to functional variation in immune responses to viruses, autoimmunity and reproductive success. This study describes the frequency distribution of
Autor:
Richard Apps, Lydia Farrell, Andrew M. Sharkey, Lucy Gardner, Sanjay Verma, Susan E. Hiby, Ashley Moffett, Louise Lathbury, C. Andrew Stewart, Jodie P. Goodridge, Leanne Masters
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Immunogenetic studies suggest that interactions between maternal killer Ig-like receptor (KIR) expressed by uterine NK (uNK) cells, and fetal HLA-C molecules on trophoblast, influence the success of human placentation. However, the exact functional r
Autor:
Olympe Chazara, Lydia Farrell, Susan E. Hiby, Francesco Colucci, James A. Traherne, Emma Lougee, Jyothi Jayaraman, Paul Norman, John Trowsdale, Stephen Tukwasibwe, Annettee Nakimuli, Peter Parham, Ashley Moffett, Alison M. Elliott, Josaphat Byamugisha, Pontiano Kaleebu, Robert Vaughan, Florence Mirembe, Neda Nemat-Gorgani
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(3)
In sub-Saharan Africans, maternal mortality is unacceptably high, with >400 deaths per 100,000 births compared with
Autor:
Richard Apps, Lydia Farrell, Håkon K. Gjessing, Olympe Chazara, Susan E. Hiby, Mary Carrington, Ashley Moffett, Per Magnus, Lill Trogstad
Human birth weight is subject to stabilizing selection; babies born too small or too large are less likely to survive. Particular combinations of maternal/fetal immune system genes are associated with pregnancies where the babies are ≤5th birth wei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a06d8f70acdb1ef106e93db11d10ac
https://europepmc.org/articles/PMC4028203/
https://europepmc.org/articles/PMC4028203/