Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Lydia E, Matesic"'
Autor:
Lorne J. Hofseth, Prakash S. Nagarkatti, Mitzi Nagarkatti, Narendra P. Singh, Lydia E. Matesic, Alex A. Chumanevich, Deepak Poudyal, Anthony J. Windust, Xiangli Cui, Anne B. Hofseth, Yu Jin
Supplementary Figure 1 from American Ginseng Suppresses Colitis through p53-Mediated Apoptosis of Inflammatory Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d639ce54e1c861621ab2d57220f831c
https://doi.org/10.1158/1940-6207.22523277
https://doi.org/10.1158/1940-6207.22523277
Autor:
Yimu Lai, Heather Doviak, Valerie K. Laney, Lisa A. Freeburg, Kia N. Zellars, Laura B. Snyder, Francis G. Spinale, Lydia E. Matesic, Amber Moore
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 321:H976-H984
Heart failure with a preserved left ventricular (LV) ejection fraction (HFpEF) often arises from a prolonged LV pressure overload (LVPO) and is accompanied by abnormal extracellular matrix (ECM) accumulation. It is now recognized that the ECM is a dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a52bf9fe7d59ef600b14679e04cbcab1
https://doi.org/10.1152/ajpheart.00032.2021
https://doi.org/10.1152/ajpheart.00032.2021
Autor:
Takahiro Kishikawa, Hiroshi Higuchi, Limei Wang, Nivedita Panch, Valerie Maymi, Sachem Best, Samuel Lee, Genso Notoya, Alex Toker, Lydia E. Matesic, Gerburg M. Wulf, Wenyi Wei, Motoyuki Otsuka, Kazuhiko Koike, John G. Clohessy, Yu-Ru Lee, Pier Paolo Pandolfi
Publikováno v:
J Clin Invest
Activation of the phosphatidylinositol 3-kinase (PI3K) signaling pathway is a pervasive event in tumorigenesis due to PI3K mutation and dysfunction of phosphatase and tensin homolog deleted on chromosome 10 (PTEN). Pharmacological inhibition of PI3K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c2ea42372ba1e42c104597ea441582
https://doi.org/10.1172/jci140436
https://doi.org/10.1172/jci140436
Autor:
Laura B, Snyder, Yimu, Lai, Heather, Doviak, Lisa A, Freeburg, Valerie K, Laney, Amber, Moore, Kia N, Zellars, Lydia E, Matesic, Francis G, Spinale
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 321(5)
Heart failure with a preserved left ventricular (LV) ejection fraction (HFpEF) often arises from a prolonged LV pressure overload (LVPO) and accompanied by abnormal extracellular matrix (ECM) accumulation. The E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0554683a9cad908f661cd4c9996e2e6f
https://pubmed.ncbi.nlm.nih.gov/34559578
https://pubmed.ncbi.nlm.nih.gov/34559578
Autor:
Edie C. Goldsmith, Amber Moore, Kia N. Zellars, Lisa A. Freeburg, Laura Snyder, Paige E. Perreault, Lauren-Ashley Michelle Duncan, Lydia E. Matesic, Francis G. Spinale
Publikováno v:
Am J Physiol Heart Circ Physiol
Ubiquitylation is a key event that regulates protein turnover, and induction of the ubiquitin ligase E3 WWP1 has been associated with age. Left ventricular hypertrophy (LVH) commonly occurs as a function of age and can cause heart failure (HF) with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22fe00ed8d17b7a3f10fb5b0e3a7153
https://europepmc.org/articles/PMC7717125/
https://europepmc.org/articles/PMC7717125/
Publikováno v:
Differentiation. 99:51-61
Maintenance of the intestinal mucosa is driven by local signals that coordinate epithelial proliferation, differentiation, and turnover in order to separate antigenic luminal contents from the host’s immune system. Breaches in this barrier promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75dfa2f29e3831e0ce90c030976119dc
https://doi.org/10.1016/j.diff.2017.12.003
https://doi.org/10.1016/j.diff.2017.12.003
Autor:
James P White, John W Baynes, Stephen L Welle, Matthew C Kostek, Lydia E Matesic, Shuichi Sato, James A Carson
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24650 (2011)
Muscle wasting that occurs with cancer cachexia is caused by an imbalance in the rates of muscle protein synthesis and degradation. The Apc(Min/+) mouse is a model of colorectal cancer that develops cachexia that is dependent on circulating IL-6. How
Externí odkaz:
https://doaj.org/article/02bbb8ae9825449995d6f5a25b6016af
Autor:
Yulia V. Shulga, Tian-Min Fu, Shang Yin Chiang, Jonathan D. Lee, Jesse Katon, Suresh Jain, Lydia E. Matesic, Ruey-Hwa Chen, Chih-Hung Hsu, Shu-Yu Lin, Jacqueline Fung, Jinfang Zhang, Wenyi Wei, Yang Zhang, Chen Shen, Tomoki Ishikawa, Lixin Wan, Ming Chen, Julie Teruya-Feldstein, Hao Wu, Pier Paolo Pandolfi, John G. Clohessy, Assaf C. Bester, Emanuele Monteleone, Yu-Ru Lee, Hao Chen, Antonella Papa
Publikováno v:
Science. 364
Supporting tumor suppression The protein PTEN is a phosphatase and tumor suppressor whose activity is often decreased in human cancers. Thus, reactivating such a protein could potentially be an effective therapy against cancer. Lee et al. identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af96518ddc17ed226263a52f638034bc
https://doi.org/10.1126/science.aau0159
https://doi.org/10.1126/science.aau0159
Autor:
Kristin R. Di Bona, John H. Richburg, Caitlin J. Murphy, Angela R Stermer, Lydia E. Matesic, Jessica L. Myers
Publikováno v:
Experimental Biology and Medicine. 241:367-374
Major progress in deciphering the role of the E3 ligase, ITCH, in animal physiology has come from the generation and identification of Itch loss-of-function mutant mice ( itchy). Mutant mice display an autoimmune-like phenotype characterized by chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b04514bc4634d3196307ccb82e11b8
https://doi.org/10.1177/1535370215610656
https://doi.org/10.1177/1535370215610656
Autor:
Masahiko Takahata, Hengwei Zhang, Lydia E. Matesic, Lan Zhao, Lianping Xing, Jian Huang, Hani A. Awad, Yi Wang, Di Chen
Publikováno v:
Stem Cells. 29:1601-1610
Patients with chronic inflammatory disorders, such as rheumatoid arthritis, often have osteoporosis due to a combination of Tumor necrosis factor-induced increased bone resorption and reduced bone formation. To test if TNF inhibits bone formation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88709c966f768e089ab44a3809ee2822
https://doi.org/10.1002/stem.703
https://doi.org/10.1002/stem.703