Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lydia B. Daniels"'
Publikováno v:
Clinica Chimica Acta. 115:369-375
Three fluorometric leukocyte beta -glucosidase assays were compared for their ability to diagnose Gaucher's disease and identify carriers of the disorder: the acid beta-glucosidase assay of Beutler and Kuhl [2], a pH 5.5-sodium taurocholate-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c1ec92f3e39c22f92236149195e933
https://doi.org/10.1016/0009-8981(81)90251-5
https://doi.org/10.1016/0009-8981(81)90251-5
Publikováno v:
Archives of Neurology. 39:550-556
Using glucocerebroside labeled with carbon 14 as the substrate, we determined that homogenates of brain tissue from both neuropathic and nonneuropathic cases of Gaucher's disease were profoundly deficient (more than 85%) in glucocerebrosidase activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a3abb6a3ce5eb7e4f9b5ad9594c251
https://doi.org/10.1001/archneur.1982.00510210020005
https://doi.org/10.1001/archneur.1982.00510210020005
Purification and characterization of a cytosolic broad specificity beta-glucosidase from human liver
Publikováno v:
Journal of Biological Chemistry. 256:13004-13013
A cytoplasmic beta-glucosidase has been isolated and purified 9,000-fold to homogeneity from the liver of a case of type 1 Gaucher's disease to a specific activity of 400,000 nmol/h/mg of protein. Although markedly elevated above control levels in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8edb79ddb7f8cb8dccbc2c09efc1601
https://doi.org/10.1016/s0021-9258(18)42997-3
https://doi.org/10.1016/s0021-9258(18)42997-3
Publikováno v:
Journal of Biological Chemistry. 259:1714-1719
Glucocerebrosidase from normal human spleen, and spleen from cases of neurologic (types 2 and 3) and nonneurologic (type 1) Gaucher's disease, was delipidated and inactivated by extraction from membranes with sodium cholate and ice-cold 1-butanol. Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34eb0d9b68c667f8dcbd97b4b0cce3c4
https://doi.org/10.1016/s0021-9258(17)43465-x
https://doi.org/10.1016/s0021-9258(17)43465-x
Publikováno v:
Journal of neuropathology and experimental neurology. 41(6)
This study explores the biochemical basis that may distinguish neurologic and nonneurologic forms of Gaucher's disease. Crude membrane preparations from spleens of controls and patients representing the three clinical categories of Gaucher's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086ffdb7ade5e4fe5e78d45047c60bf6
https://pubmed.ncbi.nlm.nih.gov/6813430
https://pubmed.ncbi.nlm.nih.gov/6813430
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 106(2)
To date, enzymatic diagnosis of Gaucher's disease via a fluorometric assay procedure which utilizes 4-methylumbelliferyl-β- d -glucopyranoside as a substrate has not been possible when liver serves as the source of enzyme since currently employed fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0862617cee265bb7dab4715c018d3b79
https://pubmed.ncbi.nlm.nih.gov/6773704
https://pubmed.ncbi.nlm.nih.gov/6773704
Autor:
Michael Palmieri, Robert H. Glew, Charles S August, Giulio D'Angio, Peter D. Nowell, Lydia B. Daniels, William L Elkins
Publikováno v:
Pediatric Research. 18:236A-236A
A 19 year-old female with non-neuronopathic Gaucher's Disease had 3 BMT's from 2 partially HLA-matched, carrier, sibling donors. Pre-BMT glucocerebrosidase (glc-ase) activity in leukocytes and liver were 13 and 9% of controls respectively. BMT #1 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98384441a6cbb441f2025c9fbaa67954
https://doi.org/10.1203/00006450-198404001-00856
https://doi.org/10.1203/00006450-198404001-00856