Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Lydia A, Afman"'
Autor:
Julia van Tuijl, Julia I.P. van Heck, Harsh Bahrar, Wieteke Broeders, Johan Wijma, Yvonne M. ten Have, Martin Giera, Heidi Zweers-van Essen, Laura Rodwell, Leo A.B. Joosten, Mihai G. Netea, Lydia A. Afman, Siroon Bekkering, Niels P. Riksen
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111103- (2024)
Summary: Brief exposure of monocytes to atherogenic molecules, such as oxidized lipoproteins, triggers a persistent pro-inflammatory phenotype, named trained immunity. In mice, transient high-fat diet leads to trained immunity, which aggravates ather
Externí odkaz:
https://doaj.org/article/2cbb666c2b6342b7a4a95757c35a8009
Autor:
Inez Trouwborst, Kelly M. Jardon, Anouk Gijbels, Gabby Hul, Edith J.M. Feskens, Lydia A. Afman, Jennifer Linge, Gijs H. Goossens, Ellen E. Blaak
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Background Body composition and body fat distribution are important predictors of cardiometabolic diseases. The etiology of cardiometabolic diseases is heterogenous, and partly driven by inter-individual differences in tissue-specific insuli
Externí odkaz:
https://doaj.org/article/10fdcf68eb9b44bca5f51b583f04498a
Autor:
Balázs Erdős, Shauna D. O’Donovan, Michiel E. Adriaens, Anouk Gijbels, Inez Trouwborst, Kelly M. Jardon, Gijs H. Goossens, Lydia A. Afman, Ellen E. Blaak, Natal A. W. van Riel, Ilja C. W. Arts
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Continuous glucose monitoring (CGM) is a promising, minimally invasive alternative to plasma glucose measurements for calibrating physiology-based mathematical models of insulin-regulated glucose metabolism, reducing the reliance on in-clini
Externí odkaz:
https://doaj.org/article/90f5b2ef888142dba762b135172e5e7c
Autor:
Anouk Gijbels, Balázs Erdős, Inez Trouwborst, Kelly M. Jardon, Michiel E. Adriaens, Gijs H. Goossens, Ellen E. Blaak, Edith J. M. Feskens, Lydia A. Afman
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Tissue-specific insulin resistance (IR) predominantly in muscle (muscle IR) or liver (liver IR) has previously been linked to distinct fasting metabolite profiles, but postprandial metabolite profiles have not been investigated in
Externí odkaz:
https://doaj.org/article/da4793d477d54990bb3a482ffe341728
Autor:
Shauna D. O’Donovan, Milena Rundle, E. Louise Thomas, Jimmy D. Bell, Gary Frost, Doris M. Jacobs, Anne Wanders, Ryan de Vries, Edwin C.M. Mariman, Marleen A. van Baak, Luc Sterkman, Max Nieuwdorp, Albert K. Groen, Ilja C.W. Arts, Natal A.W. van Riel, Lydia A. Afman
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109362- (2024)
Summary: The manifestation of metabolic deteriorations that accompany overweight and obesity can differ greatly between individuals, giving rise to a highly heterogeneous population. This inter-individual variation can impede both the provision and a
Externí odkaz:
https://doaj.org/article/1afe869749f64bceae5d59aec0da226c
Autor:
Mara P.H. van Trijp, Melany Rios-Morales, Ben Witteman, Fentaw Abegaz, Albert Gerding, Ran An, Martijn Koehorst, Bernard Evers, Katja C.V. van Dongen, Erwin G. Zoetendal, Henk Schols, Lydia A. Afman, Dirk-Jan Reijngoud, Barbara M. Bakker, Guido J. Hooiveld
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109208- (2024)
Summary: Consumption of fructo- (FOS) and galacto-oligosaccharides (GOS) has health benefits which have been linked in part to short-chain fatty acids (SCFA) production by the gut microbiota. However, detailed knowledge of this process in the human i
Externí odkaz:
https://doaj.org/article/cd41ade7fb8e4d98876000536f453c8e
Autor:
Monique Daanje, Els Siebelink, Frank Vrieling, Maartje van den Belt, Sandra van der Haar, Johanna C. Gerdessen, Sander Kersten, Diederik Esser, Lydia A. Afman
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionAn elevated postprandial glucose response is associated with an increased risk of cardiometabolic diseases. Existing research suggests large heterogeneity in the postprandial glucose responses to identical meals and food products between
Externí odkaz:
https://doaj.org/article/0c5478ce451b49c28643c23fcb1c0e78
Autor:
Shauna D. O’Donovan, Balázs Erdős, Doris M. Jacobs, Anne J. Wanders, E. Louise Thomas, Jimmy D. Bell, Milena Rundle, Gary Frost, Ilja C.W. Arts, Lydia A. Afman, Natal A.W. van Riel
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105206- (2022)
Summary: Despite the pivotal role played by elevated circulating triglyceride levels in the pathophysiology of cardio-metabolic diseases many of the indices used to quantify metabolic health focus on deviations in glucose and insulin alone. We presen
Externí odkaz:
https://doaj.org/article/b81561b698174b2a98bed0f081ce987f
Autor:
Anouk Gijbels, Sophie Schutte, Diederik Esser, Suzan Wopereis, Gerard Bryan Gonzales, Lydia A. Afman
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundWe previously showed that whole-grain wheat (WGW) consumption had beneficial effects on liver fat accumulation, as compared to refined wheat (RW). The mechanisms underlying these effects remain unclear.ObjectiveIn this study, we investigate
Externí odkaz:
https://doaj.org/article/e692dca68a7e44ae91fd7d865a0e6d1a
Autor:
Anouk Gijbels, Inez Trouwborst, Kelly M. Jardon, Gabby B. Hul, Els Siebelink, Suzanne M. Bowser, Dilemin Yildiz, Lisa Wanders, Balázs Erdos, Dick H. J. Thijssen, Edith J. M. Feskens, Gijs H. Goossens, Lydia A. Afman, Ellen E. Blaak
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/7ce8381d237942828e34502a795643ac