Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lydia, Viney"'
Autor:
Matthew Johnson, Ying Hu, Nicholas Restifo, Jared Gartner, Douglas Palmer, Shashank Patel, Maria Parkhurst, Todd Prickett, Parisa Malekzadeh, David McKenna, Zulmarie Franco, Suman Vodnala, Beau Webber, Yogin Patel, Christine Kariya, Walker Lahr, Rigel Kishton, Devikala Gurusamy, Miechaleen Diers, Natalie Wolf, Nicholas Slipek, Darin Sumstad, Lydia Viney, Tom Henley, Tilmann Bürckstümmer, Oliver Baker, Chunhua Yan, Daoud Meerzaman, Kartik Padhan, Winnie Lo, Li Jia, Drew Deniger, R Scott McIvor, Modassir Choudhry, Branden Moriarity
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/410d0e5f91994125860cead103ddfd28
Autor:
Douglas C, Palmer, Beau R, Webber, Yogin, Patel, Matthew J, Johnson, Christine M, Kariya, Walker S, Lahr, Maria R, Parkhurst, Jared J, Gartner, Todd D, Prickett, Frank J, Lowery, Rigel J, Kishton, Devikala, Gurusamy, Zulmarie, Franco, Suman K, Vodnala, Miechaleen D, Diers, Natalie K, Wolf, Nicholas J, Slipek, David H, McKenna, Darin, Sumstad, Lydia, Viney, Tom, Henley, Tilmann, Bürckstümmer, Oliver, Baker, Ying, Hu, Chunhua, Yan, Daoud, Meerzaman, Kartik, Padhan, Winnie, Lo, Parisa, Malekzadeh, Li, Jia, Drew C, Deniger, Shashank J, Patel, Paul F, Robbins, R Scott, McIvor, Modassir, Choudhry, Steven A, Rosenberg, Branden S, Moriarity, Nicholas P, Restifo
Publikováno v:
Med. 3:682-704.e8
Adoptive transfer of tumor-infiltrating lymphocytes (TIL) fails to consistently elicit tumor rejection. Manipulation of intrinsic factors that inhibit T cell effector function and neoantigen recognition may therefore improve TIL therapy outcomes. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2493e0ebec169c9a2ac88f6a46b00bbc
https://doi.org/10.1016/j.medj.2022.07.008
https://doi.org/10.1016/j.medj.2022.07.008
Autor:
Tom Henley, Elisa Arthofer, Modassir Choudhry, Beau R. Webber, Branden S. Moriarity, Emil Lou, Krishnendu Chakraborty, Christopher A. Klebanoff, Matthew Johnson, Lydia Viney
PD-1 acts as a negative regulator of T cell-mediated immune responses in the setting of persistent antigen expression, including cancer and chronic pathogen infections. Antibody-mediated blockade of the PD-1/PD-L1 axis benefits a subset of patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f80d2df72401013c80505f33877308b
https://doi.org/10.1101/2021.08.17.456714
https://doi.org/10.1101/2021.08.17.456714
Autor:
Lydia Viney, Tilmann Bürckstümmer, Mavis Agbandje-McKenna, Modassir Choudhry, Tom Henley, Mario Mietzsch, Courtnee Eddington
Publikováno v:
Journal of Virology
A major hurdle to the therapeutic potential of AAV in gene therapy lies in achieving clinically meaningful AAV doses, and secondarily, the ability to manufacture commercially viable titers of AAV to support this. By virtue of neutralizing antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36a9bf5daabba970530eb7bb9f2b2aa
https://doi.org/10.1128/jvi.02023-20
https://doi.org/10.1128/jvi.02023-20
Autor:
Matthew D. Johnson, Ying Hu, Winnie Lo, Todd D. Prickett, Douglas C. Palmer, Steven A. Rosenberg, R. Scott McIvor, Daoud Meerzaman, Li Jia, Frank J. Lowery, Parisa Malekzadeh, Walker S. Lahr, Modassir Choudhry, Tilmann Bürckstümmer, Maria R. Parkhurst, Rigel J. Kishton, Nicholas P. Restifo, Tom Henley, David H. McKenna, Devikala Gurusamy, Darin Sumstad, Chunhua Yan, Miechaleen D. Diers, Suman K. Vodnala, Branden S. Moriarity, Zulmarie Franco, Lydia Viney, Christine M. Kariya, Kartik Padhan, Yogin Patel, Natalie K. Wolf, Paul D. Robbins, Beau R. Webber, Jared J. Gartner, Drew C. Deniger, Oliver Baker, Nicholas J. Slipek, Shashank J. Patel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Neoantigen-specific T cells isolated from tumors have shown promise clinically but fail to consistently elicit durable tumor regression. Expression of the intracellular checkpoint CISH is elevated in human tumor infiltrating lymphocytes (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b30a2ebb661239363462a7e79ab7236
https://doi.org/10.1136/jitc-2020-sitc2020.0333
https://doi.org/10.1136/jitc-2020-sitc2020.0333
Autor:
Modassir Choudhry, Mavis Agbandje-McKenna, Mario Mietzsch, Tom Henley, Tilmann Bürckstümmer, Lydia Viney
Adeno-associated viruses (AAV) have attracted significant attention in the field of gene and cell therapy due to highly effective delivery of therapeutic genes into human cells. The ability to generate recombinant AAV vectors compromised of unique or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea5618ee1110c471c5625a93e7998412
https://doi.org/10.1101/2020.10.13.337261
https://doi.org/10.1101/2020.10.13.337261
Autor:
Modassir Choudhry, Miechaleen D. Diers, Nicholas P. Restifo, Tom Henley, Natalie K. Wolf, Rigel J. Kishton, Paul F. Robbins, Yogin Patel, Lydia Viney, Winnie Lo, Steven A. Rosenberg, Branden S. Moriarity, Tilmann Bürckstümmer, Maria R. Parkhurst, Christine M. Kariya, Parisa Malekzadeh, David H. McKenna, Devikala Gurusamy, Darin Sumstad, Chunhua Yan, Zulmarie Franco, Frank J. Lowery, Douglas C. Palmer, R. Scott McIvor, Daoud Meerzaman, Todd D. Prickett, Matthew Johnson, Ying Hu, Suman K. Vodnala, Nicholas J. Slipek, Shashank J. Patel, Oliver Baker, Li Jia, Drew C. Deniger, Kartik Padhan, Beau R. Webber, Walker S. Lahr, Jared J. Gartner
While neoantigen-specific tumor infiltrating lymphocytes (TIL) can be derived from in antigen-expressing tumors, their adoptive transfer fails to consistently elicit durable tumor regression. There has been much focus on the role of activation/exhaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00218cdfa78254998d1e8cb891dc1886
https://doi.org/10.1101/2020.09.24.306571
https://doi.org/10.1101/2020.09.24.306571
Autor:
Drew C. Deniger, Rigel J. Kishton, Frank J. Lowery, Ying Hu, Tilmann Bürckstümmer, Yogin Patel, Modassir Choudhry, Matthew D. Johnson, Natalie K. Wolf, Kartik Padhan, Beau R. Webber, Parisa Malekzadeh, David H. McKenna, Paul D. Robbins, Nicholas P. Restifo, Devikala Gurusamy, Steven A. Rosenberg, Tom Henley, Darin Sumstad, Maria R. Parkhurst, Chunhua Yan, Li Jia, Winifred Lo, Zulmarie Franco, Nicholas J. Slipek, R. Scott McIvor, Shashank J. Patel, Oliver Baker, Todd D. Prickett, Lydia Viney, Jared J. Gartner, Suman K. Vodnala, Miechaleen D. Diers, Walker S. Lahr, Douglas C. Palmer, Daoud Meerzaman, Branden S. Moriarity, Christine M. Kariya
Publikováno v:
SSRN Electronic Journal.
While neoantigen-specific tumor infiltrating lymphocytes (TIL) can be derived from in antigen-expressing tumors, their adoptive transfer fails to consistently elicit durable tumor regression. There has been much focus on the role of activation/exhaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd11f4a0565c0d382f87a456e33aaf1
https://doi.org/10.2139/ssrn.3751760
https://doi.org/10.2139/ssrn.3751760