Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Lyanne M. Kieneker"'
Autor:
Xavier G.L.V. Pouwels, Dominique van Mil, Lyanne M. Kieneker, Cornelis Boersma, Ronald W. van Etten, Birgitte Evers-Roeten, Hiddo J.L. Heerspink, Marc H. Hemmelder, Marloes L.P. Langelaan, Marc H.M. Thelen, Ron T. Gansevoort, Hendrik Koffijberg
Publikováno v:
EClinicalMedicine, Vol 68, Iss , Pp 102414- (2024)
Summary: Background: Chronic kidney disease (CKD) is often detected late, leading to substantial health loss and high treatment costs. Screening the general population for albuminuria identifies individuals at high risk of kidney events and cardiovas
Externí odkaz:
https://doaj.org/article/f179f7ed869b4d75914c3e48acace1d1
Autor:
Dion Groothof, Adrian Post, Harmke A. Polinder‐Bos, Nicole S. Erler, Jose L. Flores‐Guerrero, Jenny E. Kootstra‐Ros, Robert A. Pol, Martin H. deBorst, Ron T. Gansevoort, Reinold O.B. Gans, Daan Kremer, Lyanne M. Kieneker, Arjola Bano, Taulant Muka, Oscar H. Franco, Stephan J.L. Bakker
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2031-2043 (2022)
Abstract Background Creatinine is the most widely used test to estimate the glomerular filtration rate (GFR), but muscle mass as key determinant of creatinine next to renal function may confound such estimates. We explored effects of 24‐h height‐
Externí odkaz:
https://doaj.org/article/d42d1205f8b1487b97d426f71b14d20a
Autor:
Navin Suthahar, Laura M. G. Meems, Coenraad Withaar, Thomas M. Gorter, Lyanne M. Kieneker, Ron T. Gansevoort, Stephan J. L. Bakker, Dirk J. van Veldhuisen, Rudolf A. de Boer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Body-mass index (BMI), waist circumference, and waist-hip ratio are commonly used anthropometric indices of adiposity. However, over the past 10 years, several new anthropometric indices were developed, that more accurately correlated with b
Externí odkaz:
https://doaj.org/article/0379b624fd814077ae0baba31a49d8fb
Autor:
Martin F. Bourgonje, Amaal E. Abdulle, Lyanne M. Kieneker, Sacha la Bastide-van Gemert, Stephan J. L. Bakker, Ron T. Gansevoort, Sanne J. Gordijn, Harry van Goor, Arno R. Bourgonje
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 690 (2023)
Oxidative stress plays a pivotal role in cardiovascular (CV) disease, but current biomarkers used to predict CV events are still insufficient. In this study, we comparatively assessed the utility of redox-related biomarkers in predicting the risk of
Externí odkaz:
https://doaj.org/article/1e41326b72664f56a84b8d4fd8ce7fdd
Autor:
Arno R. Bourgonje, Amaal E. Abdulle, Martin F. Bourgonje, Lyanne M. Kieneker, Sacha la Bastide-van Gemert, Sanne J. Gordijn, Clara Hidden, Tom Nilsen, Ron T. Gansevoort, Douwe J. Mulder, Robin P. F. Dullaart, Martin H. de Borst, Stephan J. L. Bakker, Harry van Goor
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 338 (2023)
Circulating levels of neutrophil gelatinase-associated lipocalin (NGAL) have been associated with acute kidney injury and the severity and progression of chronic kidney disease (CKD). This study investigated its potential utility as a biomarker for t
Externí odkaz:
https://doaj.org/article/d685596b90284a7498c97ce552aa1ab0
Autor:
Arno R. Bourgonje, Eline H. van den Berg, Lyanne M. Kieneker, Tom Nilsen, Clara Hidden, Stephan J. L. Bakker, Hans Blokzijl, Robin P. F. Dullaart, Harry van Goor, Amaal E. Abdulle
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15708 (2022)
Metabolic-associated fatty liver disease (MAFLD) is characterized by hepatic steatosis, metabolic dysregulation, and neutrophilic inflammation. In this study, we hypothesized that systemic levels of plasma calprotectin, as a biomarker of neutrophilic
Externí odkaz:
https://doaj.org/article/d657dd0fb89c4dcd832b9802d53e34ab
Autor:
Arno R. Bourgonje, Amaal E. Abdulle, Martin F. Bourgonje, S. Heleen Binnenmars, Sanne J. Gordijn, Marian L.C. Bulthuis, Sacha la Bastide-van Gemert, Lyanne M. Kieneker, Ron T. Gansevoort, Stephan J.L. Bakker, Douwe J. Mulder, Andreas Pasch, Martin H. de Borst, Harry van Goor
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102211- (2021)
Background: Serum sulfhydryl groups (R-SH, free thiols) reliably reflect the systemic redox status in health and disease. As oxidation of R-SH occurs rapidly by reactive oxygen species (ROS), oxidative stress is accompanied by reduced levels of free
Externí odkaz:
https://doaj.org/article/13190ebf6c0d40ec9c0849727f2a526b
Autor:
Amaal E. Abdulle, Arno R. Bourgonje, Lyanne M. Kieneker, Anne M. Koning, S. la Bastide-van Gemert, Marian L. C. Bulthuis, Gerard Dijkstra, Klaas Nico Faber, Robin P. F. Dullaart, Stephan J. L. Bakker, Reinold O. B. Gans, Ron T. Gansevoort, Douwe J. Mulder, Andreas Pasch, Harry van Goor
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Serum free thiols (R-SH, sulfhydryl groups) reliably reflect systemic oxidative stress. Since serum free thiols are rapidly oxidized by reactive species, systemic oxidative stress is generally associated with reduced serum free th
Externí odkaz:
https://doaj.org/article/db379de50d37452f8d3a0b7d37b68ae5
Autor:
Yook Chin Chia, Lyanne M. Kieneker, Gaston van Hassel, S. Heleen Binnenmars, Ilja M. Nolte, Jelmer J. van Zanden, Peter van der Meer, Gerjan Navis, Adriaan A. Voors, Stephan J. L. Bakker, Martin H. De Borst, Michele F. Eisenga
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 11 (2021)
Background The cause of heart failure with preserved ejection fraction (HFpEF) is poorly understood, and specific therapies are lacking. Previous studies suggested that inflammation plays a role in the development of HFpEF. Herein, we aimed to invest
Externí odkaz:
https://doaj.org/article/c84d9413e7c943afb375bbad47c31c9f
Autor:
Martin F. Bourgonje, Arno R. Bourgonje, Amaal E. Abdulle, Lyanne M. Kieneker, Sacha la Bastide-van Gemert, Ron T. Gansevoort, Stephan J. L. Bakker, Douwe J. Mulder, Andreas Pasch, Jumana Saleh, Sanne J. Gordijn, Harry van Goor
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free thiols (R-SH, sulfhydryl groups), which are key components of
Externí odkaz:
https://doaj.org/article/fe63271d27af40cbbfa86f504ca4760d