Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lyang-Ja Lee"'
Autor:
Ichiro Wakabayashi, Mikio Marumo, Daisuke Nonaka, Tomoko Shimomura, Ryoji Eguchi, Lyang-Ja Lee, Kenji Tanaka, Katsuhiko Hatake
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147297 (2016)
The purpose of this study was to explore the peptides that are related to acute reduction of blood pressure after alcohol drinking. Venous blood was collected from male healthy volunteers before and after drinking white wine (3 ml/kg weight) containi
Externí odkaz:
https://doaj.org/article/59ab54ee00554a299d4e8c1a33c220b3
Autor:
Salunya Tancharoen, Takashi Matsuyama, Ko-Ichi Kawahara, Kenji Tanaka, Lyang-Ja Lee, Miho Machigashira, Kazuyuki Noguchi, Takashi Ito, Takahisa Imamura, Jan Potempa, Kiyoshi Kikuchi, Ikuro Maruyama
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117775 (2015)
BACKGROUND/PURPOSE:Lysine-specific gingipain (Kgp) is a virulence factor secreted from Porphyromonas gingivalis (P. gingivalis), a major etiological bacterium of periodontal disease. Keratin intermediate filaments maintain the structural integrity of
Externí odkaz:
https://doaj.org/article/25a0bfa53c9d4772b01b5f4e23f90f8b
Autor:
Yumiko Nakano, Masamitsu Takatama, Kyoichi Asada, Mikio Shoji, Takeshi Kuroda, Motohisa Kojo, Mami Takemoto, Yasuto Higashi, Yoshiki Takao, Yoshio Ikeda, Toru Yamashita, Noriyuki Kimura, Koichi Okamoto, Kentaro Deguchi, Ryuta Morihara, Jingwei Shang, Nozomi Hishikawa, Yasuyuki Ohta, Takehito Senga, Yosuke Osakada, Koji Abe, Kenji Tanaka, Kenjiro Ono, Yosuke Wakutani, Etsuro Matsubara, Lyang Ja Lee, Masaki Ikeda, Xiaowen Shi
Publikováno v:
Journal of Alzheimer's Disease
Background: Because dementia is an emerging problem in the world, biochemical markers of cerebrospinal fluid (CSF) and radio-isotopic analyses are helpful for diagnosing Alzheimer’s disease (AD). Although blood sample is more feasible and plausible
Autor:
Takahiro Ueda, Ichiro Wakabayashi, Lyang-Ja Lee, Tanaka Kenji, Joji Kotani, Naomi Mambo, Daisuke Nonaka
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis
Complication of disseminated intravascular coagulation (DIC) is a determinant of the prognosis for patients with sepsis. The purpose of this study was to find DIC-related peptides in blood for prediction and early diagnosis of DIC in patients with se
Autor:
Jun Mukai, Lyang-Ja Lee, Makoto Ohki, Kenji Tanaka, Mikio Marumo, Daisuke Nonaka, Ichiro Wakabayashi, Kagehiro Uchida
Publikováno v:
Clinica Chimica Acta. 470:46-50
The cysteine residue on transthyretin (TTR) is susceptible to be oxidized, and serum cysteinylated TTR (Cys-TTR) level is thought to reflect oxidative stress. The purpose of this study was to elucidate the relationship between Cys-TTR and arterial st
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Although orphan G protein-coupled receptors (GPCRs) have been used as targets to discover unidentified natural ligands, increasing numbers of non-GPCRs have been found to mediate important biological functions. Bioinformatics of genome and cDNA resou
Autor:
Yuji Naito, Osamu Dohi, Eigo Otsuji, Yasuko Hirai, Yasuki Higashimura, Lyang-Ja Lee, Takeshi Ishikawa, Hideyuki Konishi, Katsura Mizushima, Kazuhiko Uchiyama, Yoshito Itoh, Tomohisa Takagi, Kazuhiro Katada, Asada Kyoichi, Tetsuya Okayama, Osamu Handa, Nobuaki Yagi, Naohisa Yoshida, Kenji Tanaka, Yoshiaki Kuriu, Daisuke Nonaka, Masayoshi Nakanishi, Kazuhiro Kamada
Publikováno v:
Journal of gastroenterology. 53(11)
Colorectal cancer (CRC) is one of the most predominant types of cancer, and it is the fourth most common cause of cancer-related death and it is important to diagnose CRC in early stage to decrease the mortality by CRC. In our previous study, we iden
Autor:
Yoshihiko Araki, Daisuke Nonaka, Kenji Takamori, Michio Banzai, Shuichiro Endo, Koyo Yoshida, Lyang-Ja Lee, Hitoshi Ishikawa, Tanaka Kenji, Kensuke Hamamura, Michio Nojima, Mayuko Maruyama, Mitsuaki Yanagida, Satoru Takeda, Atsushi Tajima
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 39:1440-1448
To date, numerous studies have searched for candidate molecules or clinical examination methods as potential biomarkers for monitoring intractable diseases, such as carcinomas. Evidence accumulated over the past decade shows that many proteolytic pep
Autor:
Asada Kyoichi, Yoshihiko Araki, Hitoshi Ishikawa, Daisuke Nonaka, Kenji Takamori, Takeaki Nitto, Mitsuaki Yanagida, Teruto Hashiguchi, Kuronaka Noriko, Koyo Yoshida, Tanaka Kenji, Lyang-Ja Lee, Hiroshi Yoshitake, Michio Nojima, Mayuko Maruyama, Ikuro Maruyama, Emiko Yoshida, Atsushi Tajima
Publikováno v:
PROTEOMICS. 11:2727-2737
We have recently developed a new target plate (BLOTCHIP®) for MALDI-MS. An advantage of this procedure is that it does not require the lowering of protein concentrations in test samples prior to analysis. Accordingly, this new technology enables the
Autor:
Yoshiki Seino, Katsumi Suzuki, Yasushi Matsuoka, Toshitaka Nakamura, Hiroyuki Tanaka, Lyang-Ja Lee, Ken'Ichiro Narusawa
Publikováno v:
Journal of Bone and Mineral Research. 10:1853-1864
We compared the effect of administration of recombinant human insulin-like growth factor-1 (rhIGF-1) alone or the rhIGF-1/IGF binding protein-3 (IGFBP-3) complex on osteopenia in rats. Female Sprague-Dawley rats (8 months old) underwent combined ovar