Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Lyakisheva A"'
Autor:
Vakili, Mohammad Ghazi, Gorgulla, Christoph, Nigam, AkshatKumar, Bezrukov, Dmitry, Varoli, Daniel, Aliper, Alex, Polykovsky, Daniil, Das, Krishna M. Padmanabha, Snider, Jamie, Lyakisheva, Anna, Mansob, Ardalan Hosseini, Yao, Zhong, Bitar, Lela, Radchenko, Eugene, Ding, Xiao, Liu, Jinxin, Meng, Fanye, Ren, Feng, Cao, Yudong, Stagljar, Igor, Aspuru-Guzik, Alán, Zhavoronkov, Alex
The discovery of small molecules with therapeutic potential is a long-standing challenge in chemistry and biology. Researchers have increasingly leveraged novel computational techniques to streamline the drug development process to increase hit rates
Externí odkaz:
http://arxiv.org/abs/2402.08210
Autor:
Phadnis, Vaishnavi V., Snider, Jamie, Varadharajan, Venkateshwari, Ramachandiran, Iyappan, Deik, Amy A., Lai, Zon Weng, Kunchok, Tenzin, Eaton, Elinor Ng, Sebastiany, Carolin, Lyakisheva, Anna, Vaccaro, Kyle D., Allen, Juliet, Yao, Zhong, Wong, Victoria, Geng, Betty, Weiskopf, Kipp, Clish, Clary B., Brown, J. Mark, Stagljar, Igor, Weinberg, Robert A., Henry, Whitney S.
Publikováno v:
In Cell Reports 26 September 2023 42(9)
Autor:
Vaishnavi V. Phadnis, Jamie Snider, Venkateshwari Varadharajan, Iyappan Ramachandiran, Amy A. Deik, Zon Weng Lai, Tenzin Kunchok, Elinor Ng Eaton, Carolin Sebastiany, Anna Lyakisheva, Kyle D. Vaccaro, Juliet Allen, Zhong Yao, Victoria Wong, Betty Geng, Kipp Weiskopf, Clary B. Clish, J. Mark Brown, Igor Stagljar, Robert A. Weinberg, Whitney S. Henry
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113023- (2023)
Summary: Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer. Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those containing the polyunsaturated fatty acid arachidonic acid (AA),
Externí odkaz:
https://doaj.org/article/f1a03612f457448787c70b44eca61b6d
Autor:
Sun Jin Kim, Zhong Yao, Morgan C. Marsh, Debra M. Eckert, Michael S. Kay, Anna Lyakisheva, Maria Pasic, Aiyush Bansal, Chaim Birnboim, Prabhat Jha, Yannick Galipeau, Marc-André Langlois, Julio C. Delgado, Marc G. Elgort, Robert A. Campbell, Elizabeth A. Middleton, Igor Stagljar, Shawn C. Owen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Neutralisation assays are key to understanding immune responses to SARS-CoV-2 infection or vaccination. Here, the authors report a surrogate virus neutralization assay called Neu-SATiN, which measures neutralization directly from sera, and allows eas
Externí odkaz:
https://doaj.org/article/cb13b4c7a86945c89b15956fb496cbcb
Publikováno v:
In Current Opinion in Chemical Biology February 2022 66
Autor:
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 2, Pp n/a-n/a (2022)
Abstract Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a chloride and bicarbonate channel in secretory epithelia with a critical role in maintaining fluid homeostasis. Mutations in CFTR are associated with Cystic Fibrosis (CF), the mo
Externí odkaz:
https://doaj.org/article/2333634eb31448bfa35a483208141fd8
Autor:
Zhong Yao, Farzaneh Aboualizadeh, Jason Kroll, Indira Akula, Jamie Snider, Anna Lyakisheva, Priscilla Tang, Max Kotlyar, Igor Jurisica, Mike Boxem, Igor Stagljar
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Protein-protein interactions are fundamental to the regulation of protein activity and cellular phyisology. Here the authors present Split Intein-Mediated Protein Ligation, which uses bait and prey proteins fused to intein fragments to generate singl
Externí odkaz:
https://doaj.org/article/d7c200701845452a9c8b0403041b6f6f
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Publikováno v:
Experimental and Clinical Gastroenterology. :161-165
We present a rare clinical case of Wilson-C onovalov disease in a patient after a new coronavirus infection. The development of her neurological symptoms, which allowed to specify the etiology of the already existing liver damage, may have been provo
Publikováno v:
Economics Profession Business. :74-83
In the article, in the context of the topic of socio-economic development of the territory, the mechanism for introducing a new and promising form of citizens» participation in solving issues of local importance — initiative projects is considered