Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ly Q. Hong-Brown"'
Publikováno v:
J Biol Chem
Extracellular vesicles (EVs) play important roles in cell-cell communication. In budding yeast (Saccharomyces cerevisiae), EVs function as carriers to transport cargo proteins into the periplasm for storage during glucose starvation. However, intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e0bdb94ee5be5d5f00f22b98b6efee
https://europepmc.org/articles/PMC7049962/
https://europepmc.org/articles/PMC7049962/
Publikováno v:
DNA and Cell Biology. 36:909-921
Exosomes are small vesicles secreted by a variety of cell types under physiological and pathological conditions. When Saccharomyces cerevisiae are grown in low glucose, small vesicles carrying more than 300 proteins with diverse biological functions
Publikováno v:
Journal of Cellular Biochemistry. 116:91-101
A variety of stressors including alcohol (EtOH) are known to induce collagen production and fibrotic diseases. Matrix metalloproteinases (MMP) play an important role in regulating fibrosis, but little is known regarding the relationship between EtOH
Publikováno v:
Alcoholism, clinical and experimental research. 41(5)
Background Excessive alcohol (EtOH) consumption causes an imbalance in protein metabolism. EtOH impairs protein synthesis in C2C12 myoblasts via a FoxO1-AMPK-TSC2-mTORC1 pathway and also induces protein degradation. As the underlying regulatory signa
Publikováno v:
Journal of Biological Chemistry. 2/28/2020, Vol. 295 Issue 9, p2650-2663. 14p.
Publikováno v:
American Journal of Physiology-Cell Physiology. 302:C1557-C1565
Leucine (Leu) and insulin both stimulate muscle protein synthesis, albeit at least in part via separate signaling pathways. While alcohol (EtOH) suppresses insulin-stimulated protein synthesis in cultured myocytes, its ability to disrupt Leu signalin
Autor:
Robert A. Frost, Pengxiang She, Anne M. Pruznak, Rachel Lantry, Ly Q. Hong-Brown, Charles H. Lang, Thomas C. Vary
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 295:E964-E973
The mechanism by which human immunodeficiency virus (HIV)-1 infection in humans leads to the erosion of lean body mass is poorly defined. Therefore, the purpose of the present study was to determine whether transgenic (Tg) rats that constitutively ov
Publikováno v:
Journal of Biological Chemistry. 282:3702-3712
Ethanol decreases protein synthesis in cells, although the underlying regulatory mechanisms of this process are not fully established. In the present study incubation of C2C12 myocytes with 100 mm EtOH decreased protein synthesis while markedly incre
Publikováno v:
Alcoholism: Clinical and Experimental Research. 30:1297-1307
Background: Alcohol and the antiretroviral drug indinavir (Ind) decrease protein synthesis in skeletal muscle under in vivo and in vitro conditions. The goal of the present study was to identify signaling mechanisms responsible for the inhibitory eff
Publikováno v:
American Journal of Physiology-Cell Physiology. 287:C1482-C1492
Anti-retroviral therapy promotes clinical, immunologic, and virologic improvement in human immunodeficiency virus-infected patients. Whereas this therapy adversely affects carbohydrate and lipid metabolism, the effects of anti-retroviral drugs on mus