Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Ly P. Vu"'
Autor:
Maryam Ghashghaei, Yilin Liu, James Ettles, Giuseppe Bombaci, Niveditha Ramkumar, Zongmin Liu, Leo Escano, Sandra Spencer Miko, Yerin Kim, Joseph A. Waldron, Kim Do, Kyle MacPherson, Katie A. Yuen, Thilelli Taibi, Marty Yue, Aaremish Arsalan, Zhen Jin, Glenn Edin, Aly Karsan, Gregg B. Morin, Florian Kuchenbauer, Fabiana Perna, Martin Bushell, Ly P. Vu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Protein synthesis is frequently deregulated during tumorigenesis. However, the precise contexts of selective translational control and the regulators of such mechanisms in cancer is poorly understood. Here, we uncovered CNOT3, a subunit of t
Externí odkaz:
https://doaj.org/article/70b7701b4c0b40d88cc303cdcb9178b8
Autor:
Maryam Ghashghaei, Yilin Liu, James Ettles, Giuseppe Bombaci, Niveditha Ramkumar, Zongmin Liu, Leo Escano, Sandra Spencer Miko, Yerin Kim, Joseph A. Waldron, Kim Do, Kyle MacPherson, Katie A. Yuen, Thilelli Taibi, Marty Yue, Aaremish Arsalan, Zhen Jin, Glenn Edin, Aly Karsan, Gregg B. Morin, Florian Kuchenbauer, Fabiana Perna, Martin Bushell, Ly P. Vu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/0f59f076c7fc4285a49794e5de178a16
Autor:
Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Eren L. Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace Y. Q. Han, Aspen J. Pierson, Michael Xiao, Xuejing Yang, Lindsey M. Kuehm, Yuning Hong, Diu T. T. Nguyen, Gabriela Chiosis, Alex Kentsis, Christina Leslie, Ly P. Vu, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Tissue homeostasis is maintained after stress by engaging and activating the hematopoietic stem and progenitor compartments in the blood. Hematopoietic stem cells (HSCs) are essential for long-term repopulation after secondary transplantatio
Externí odkaz:
https://doaj.org/article/a849e3d3deda463181789ab17c11b2cd
Autor:
Diu T. T. Nguyen, Yuheng Lu, Eren L. Chu, Xuejing Yang, Sun-Mi Park, Zi-Ning Choo, Christopher R. Chin, Camila Prieto, Alexandra Schurer, Ersilia Barin, Angela M. Savino, Saroj Gourkanti, Payal Patel, Ly P. Vu, Christina S. Leslie, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract The cell-context dependency for RNA binding proteins (RBPs) mediated control of stem cell fate remains to be defined. Here we adapt the HyperTRIBE method using an RBP fused to a Drosophila RNA editing enzyme (ADAR) to globally map the mRNA t
Externí odkaz:
https://doaj.org/article/57d9dd401d274463904c8c3f4b95b1ec
Autor:
Yuanming Cheng, Hanzhi Luo, Franco Izzo, Brian F. Pickering, Diu Nguyen, Robert Myers, Alexandra Schurer, Saroj Gourkanti, Jens C. Brüning, Ly P. Vu, Samie R. Jaffrey, Dan A. Landau, Michael G. Kharas
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1703-1716.e6 (2019)
Summary: Stem cells balance cellular fates through asymmetric and symmetric divisions in order to self-renew or to generate downstream progenitors. Symmetric commitment divisions in stem cells are required for rapid regeneration during tissue damage
Externí odkaz:
https://doaj.org/article/d0575c334f4841de919b97361dfd2bba
Autor:
Fabiana Perna, Ly P. Vu, Maria Themeli, Sonja Kriks, Ruben Hoya-Arias, Raya Khanin, Todd Hricik, Jorge Mansilla-Soto, Eirini P. Papapetrou, Ross L. Levine, Lorenz Studer, Michel Sadelain, Stephen D. Nimer
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 658-669 (2015)
Epigenetic regulation of key transcriptional programs is a critical mechanism that controls hematopoietic development, and, thus, aberrant expression patterns or mutations in epigenetic regulators occur frequently in hematologic malignancies. We demo
Externí odkaz:
https://doaj.org/article/063ec1c46d1b41b4ac0026122cb9bb13
Autor:
Ly P. Vu, Fabiana Perna, Lan Wang, Francesca Voza, Maria E. Figueroa, Paul Tempst, Hediye Erdjument-Bromage, Rui Gao, Sisi Chen, Elisabeth Paietta, Tony Deblasio, Ari Melnick, Yan Liu, Xinyang Zhao, Stephen D. Nimer
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1625-1638 (2013)
Defining the role of epigenetic regulators in hematopoiesis has become critically important, because recurrent mutations or aberrant expression of these genes has been identified in both myeloid and lymphoid hematological malignancies. We found that
Externí odkaz:
https://doaj.org/article/23494b692f7d460ba04c664afe18b963
Akademický článek
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Publikováno v:
Biochemistry and Cell Biology. 101:131-147
RNA deadenylation, the process of shortening of the 3′ poly(A) tail of an RNA molecule, is one of the key steps of post-transcriptional regulation of gene expression in eukaryotic cells. PAN2/3 and CCR4-NOT (CNOT) are the two dominant RNA deadenyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d138671c46a63d778a738919d2239ef0
https://doi.org/10.1139/bcb-2022-0325
https://doi.org/10.1139/bcb-2022-0325
Publikováno v:
International Journal of Hematology. 117:807-820
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2263785634e84bae02efa0b4e7b62c6
https://doi.org/10.1007/s12185-023-03576-0
https://doi.org/10.1007/s12185-023-03576-0