Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lvye Chai"'
Autor:
Minjie Li, Cheng Zhu, Ye Yuan, Xiangyu Huang, Lei Wu, Jiayang Wu, Hongyan Yin, Lvye Chai, Weiyu Qu, Ya Yan, Pingwei Li, Xin Li
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111145- (2024)
Summary: Host immune system has evolved multiple sensors to detect pathogenic and damaged DNA, where precise regulation is critical for distinguishing self from non-self. Our previous studies showed that NLRC3 is an inhibitory nucleic acid sensor tha
Externí odkaz:
https://doaj.org/article/f1b93279750c4c7999b7bd0c343a66b9
Autor:
Xiangyu Huang, Zhenchao Zhao, Cheng Zhu, Lvye Chai, Ya Yan, Ye Yuan, Lei Wu, Minjie Li, Xiaohan Jiang, Haiwei Wang, Zheng Liu, Pingwei Li, Xin Li
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012398 (2024)
Inflammasomes play pivotal roles in inflammation by processing and promoting the secretion of IL-1β. Caspase-1 is involved in the maturation of IL-1β and IL-18, while human caspase-4 specifically processes IL-18. Recent structural studies of caspas
Externí odkaz:
https://doaj.org/article/22ef453e94bc4d4cbee1680e300656b8
Autor:
Ya Yan, Lei Wu, Ye Yuan, Haiwei Wang, Hongyan Yin, Minjie Li, Lvye Chai, Ruiying Liang, Yanjie Liu, Dongming Zhao, Junji Xing, Pingwei Li, Xin Li
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011641 (2023)
RNA viruses cause numerous infectious diseases in humans and animals. The crosstalk between RNA viruses and the innate DNA sensing pathways attracts increasing attention. Recent studies showed that the cGAS-STING pathway plays an important role in re
Externí odkaz:
https://doaj.org/article/fa2e8951319f451db742fcf341b43519