Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Luzviminda Feeney"'
Autor:
Zhenghui Li, Michael E. Johnson, Robert Lafyatis, Sarah T. Arron, Jorge Gil C. Angeles, Luzviminda Feeney, Michelle Dimon, Tammara A. Wood, Michael L. Whitfield
Publikováno v:
The Journal of investigative dermatology
Previous studies have suggested a role for pathogens as a trigger of systemic sclerosis (SSc), although neither a pathogen nor a mechanism of pathogenesis is known. Here we show enrichment of Rhodotorula sequences in the skin of patients with early,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3d375e73f9ce229f220a9fc68dc05d
Autor:
Homayoun Moslehi, V. Feichtenschlager, Timothy H. McCalmont, Lily Peng, Kim Chong, Gary A. Green, Susana Ortiz-Urda, Luzviminda Feeney, Christian Posch, Tom L. Phillips, Anoosheh Ebaee, Adil Daud, Michelle Dimon, Philip E. LeBoit
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 110, iss 10
Activating mutations in the neuroblastoma rat sarcoma viral oncogene homolog (NRAS) gene are common genetic events in malignant melanoma being found in 15–25% of cases. NRAS is thought to activate both mitogen activated protein kinase (MAPK) and PI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6bb2f8ff6808e99d2eb632b50e15f8
https://doi.org/10.1073/pnas.1216013110
https://doi.org/10.1073/pnas.1216013110
Autor:
Luzviminda Feeney, David Dankort, Tiffany K. Dong, Wade Wilson, Stephanie Bruguera, Dennis H. Oh, Ingrid Revet, James E. Cleaver
Publikováno v:
Proceedings of the National Academy of Sciences. 108:8663-8667
The phosphorylation of H2Ax on its S139 site, γH2Ax, is important during DNA double-strand repair and is considered necessary for assembly of repair complexes, but its functional role after other kinds of DNA damage is less clear. We have measured t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db9c7116b4ace3f88eadd8aeb8638cb
https://doi.org/10.1073/pnas.1105866108
https://doi.org/10.1073/pnas.1105866108
Publikováno v:
Proceedings of the National Academy of Sciences. 107:6870-6875
UV irradiation induces histone variant H2AX phosphorylated on serine 139 (gammaH2AX) foci and high levels of pan-nuclear gammaH2AX staining without foci, but the significance of this finding is still uncertain. We examined the formation of gammaH2AX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a340df3176d403ab16a1e41480f8f637
https://doi.org/10.1073/pnas.1002175107
https://doi.org/10.1073/pnas.1002175107
Publikováno v:
DNA Repair. 6:1794-1804
Xeroderma pigmentosum variant (XP-V) cells lack the damage-specific DNA polymerase eta and have normal excision repair but show defective DNA replication after UV irradiation. Previous studies using cells transformed with SV40 or HPV16 (E6/E7) sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b80a6a03ae2fd71564f4e55ea98d7b3
https://doi.org/10.1016/j.dnarep.2007.07.005
https://doi.org/10.1016/j.dnarep.2007.07.005
Autor:
Charles L. Limoli, S de Feraudy, D. Karentz, Luzviminda Feeney, T M Marti, James E. Cleaver, Erich Giedzinski
Publikováno v:
Oncogene. 26:5713-5721
Hydroxyurea reduces DNA replication by nucleotide deprivation, whereas UV damage generates DNA photoproducts that directly block replication fork progression. We show that the low fidelity class Y polymerase Pol eta is recruited to proliferating cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8880a605e8b5d52f6a20529896494d5
https://doi.org/10.1038/sj.onc.1210385
https://doi.org/10.1038/sj.onc.1210385
Publikováno v:
Journal of Investigative Dermatology. 127(2):493-496
TO THE EDITOR Xeroderma pigmentosum (XP) is an inherited human disorder in which patients have greatly elevated incidence of solar-induced cancers caused by mutations in genes for nucleotide excision repair or polymerase η that are required for repa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ad7d64f7672d41ade6db74f19bf6f6
Publikováno v:
Journal of Clinical & Experimental Dermatology Research.
Voriconazole is an effective anti-fungal triazole commonly used in bone marrow and solid organ transplant recipients. However, reports of accelerated development of aggressive squamous cell carcinomas in immunocompromised patients are documented foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55e6b47adb84e549221c574847f3bf01
https://doi.org/10.4172/2155-9554.1000173
https://doi.org/10.4172/2155-9554.1000173
Publikováno v:
Mutagenesis. 10:457-462
Three processes associated with DNA damage and genomic instability have been defined experimentally as operating during or soon after DNA replication : mismatch repair, post-replication repair and sister chromatid exchange. All these processes appear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435a851eca576ec64c4624a49b0c0330
https://doi.org/10.1093/mutage/10.5.457
https://doi.org/10.1093/mutage/10.5.457
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 289:107-114
Treatment of cells with α-difluoromethylornithine (DFMO), which leads to the intracellular depletion of the polyamnes putrescine and spermidine, is known to increase the cell kiling induced by the DNA cross-linking chemotherapeutic agent 1,3-bis(2-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::943293e5ecb383aa5e54e7b45315ab63
https://doi.org/10.1016/0027-5107(93)90136-4
https://doi.org/10.1016/0027-5107(93)90136-4