Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Luz Orfila"'
Autor:
Mathieu Horeau, Melissa Delalande, Martine Ropert, Patricia Leroyer, Brice Martin, Luz Orfila, Olivier Loréal, Frédéric Derbré
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1989-1998 (2024)
Abstract Background Previous data in humans suggest that extreme physical inactivity (EPI) affects iron metabolism differently between sexes. Our objective was to deepen the underlying mechanisms by studying rats of both sexes exposed to hindlimb unl
Externí odkaz:
https://doaj.org/article/73f6696c3f3f4108a183450234b03960
Autor:
Manon Gouez, Amélie Rébillard, Amandine Thomas, Sabine Beaumel, Eva-Laure Matera, Etienne Gouraud, Luz Orfila, Brice Martin, Olivia Pérol, Cédric Chaveroux, Erica N. Chirico, Charles Dumontet, Béatrice Fervers, Vincent Pialoux
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acute exercise induces transient modifications in the tumor microenvironment and has been linked to reduced tumor growth along with increased infiltration of immune cells within the tumor in mouse models. In this study, we aimed to evaluate the impac
Externí odkaz:
https://doaj.org/article/a6028b7e82b6439a813d3c93a4bc225c
Autor:
David Martin, Kévin Nay, François Robin, Amélie Rebillard, Luz Orfila, Brice Martin, Patricia Leroyer, Pascal Guggenbuhl, Suzanne Dufresne, Philippe Noirez, Martine Ropert, Olivier Loréal, Frédéric Derbré
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1250-1261 (2022)
Abstract Background Iron excess has been proposed as an essential factor in skeletal muscle wasting. Studies have reported correlations between muscle iron accumulation and atrophy, either through ageing or by using experimental models of secondary i
Externí odkaz:
https://doaj.org/article/47ed2e68de054bf48f64a3e1c0303327
Autor:
Suzanne, Dufresne, Cindy, Richard, Arthur, Dieumegard, Luz, Orfila, Gregory, Delpon, Sophie, Chiavassa, Brice, Martin, Laurent, Rouvière, Jean-Michel, Escoffre, Edward, Oujagir, Baudouin, Denis de Senneville, Ayache, Bouakaz, Nathalie, Rioux-Leclercq, Vincent, Potiron, Amélie, Rébillard
Publikováno v:
Cancers
Cancers, MDPI, 2021, 13 (21), pp.5402. ⟨10.3390/cancers13215402⟩
Cancers, 2021, 13 (21), pp.5402. ⟨10.3390/cancers13215402⟩
Volume 13
Issue 21
Cancers, Vol 13, Iss 5402, p 5402 (2021)
Cancers, MDPI, 2021, 13 (21), pp.5402. ⟨10.3390/cancers13215402⟩
Cancers, 2021, 13 (21), pp.5402. ⟨10.3390/cancers13215402⟩
Volume 13
Issue 21
Cancers, Vol 13, Iss 5402, p 5402 (2021)
Simple Summary Physical activity is increasingly incorporated in cancer patient health care as a strategy to improve survival outcomes. However, its effects on treatment efficiency remains unclear. The aim of our preclinical study is to evaluate whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::25dbb4451a30617f30e8d4cc9aab56fa
https://hal.archives-ouvertes.fr/hal-03453439
https://hal.archives-ouvertes.fr/hal-03453439
Autor:
Brice Martin, Frédéric Derbré, Christelle Koechlin-Ramonatxo, Kevin Nay, David J. R. Martin, Olivier Loréal, Mathieu Horeau, Thibaut Cavey, Moussa Kenawi, Dany Saligaut, Marie-Laure Island, Luz Orfila, Martine Ropert
New findings - What is the central question of this study? Could skeletal muscle be involved in microgravity-induced iron misdistribution by modulating expression of hepcidin, the master regulator of iron metabolism? What is the main finding and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea1821dcf1fad81fe78f73fbea76a0f
https://acuresearchbank.acu.edu.au/item/8w476/intermittent-reloading-does-not-prevent-reduction-in-iron-availability-and-hepcidin-upregulation-caused-by-hindlimb-unloading
https://acuresearchbank.acu.edu.au/item/8w476/intermittent-reloading-does-not-prevent-reduction-in-iron-availability-and-hepcidin-upregulation-caused-by-hindlimb-unloading
Autor:
Olivier Loréal, Loïc Treffel, Martine Ropert, Arnaud Beck, Sarah Rochdi, Luz Orfila, Guillemette Gauquelin-Koch, Frédéric Derbré, Christelle Koechlin-Ramonatxo, Marie-Laure Island, Marie-Pierre Bareille, Kevin Nay
Publikováno v:
FASEB Journal
FASEB Journal, 2020, 34 (11), pp.14920-14929. ⟨10.1096/fj.202001199RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (11), pp.14920-14929. ⟨10.1096/fj.202001199RR⟩
FASEB Journal, 2020, 34 (11), pp.14920-14929. ⟨10.1096/fj.202001199RR⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2020, 34 (11), pp.14920-14929. ⟨10.1096/fj.202001199RR⟩
International audience; The objective of the present study was to determine the effects of dry immersion, an innovative ground-based human model of simulated microgravity and extreme physical inactivity, on iron homeostasis and distribution. Twenty y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fa89610591a685e5ab92952a6c8083
https://hal.science/hal-02946797
https://hal.science/hal-02946797
Autor:
Trina Colman, Francisco Arvelo, Elizabeth Merentes, María Rodríguez, Luz Orfila, Masahisa Hasegawa
Publikováno v:
Journal of Ethnopharmacology. 71:449-456
The cytotoxicity of two protoberberine alkaloids: berberine and lincangenine, their 8-hydroxy-7,8-dihydro-derivatives and tetrahydroprotoberberine:thaicanine, was evaluated. The cellular responses through the [3-(4,5-dimethylthiazol-2-yl)-2,5-dipheny
Publikováno v:
Carcinogenesis. 11:541-547
Trenbolone, a synthetic androgen together with testosterone, a natural androgen, were studied comparatively for their transforming effects on Syrian hamster embryo (SHE) cells. The data indicated that both androgens exhibited weak positive complete t
Autor:
Dominique Lagadic-Gossmann, André Guillouzo, Alan Anderson, Azzedine Atfi, Florence Joannard, David Gilot, Mary Rissel, Luz Orfila-Lefeuvre
Publikováno v:
Toxicology Letters
Toxicology Letters, 2006, 161 (1), pp.61-72. ⟨10.1016/j.toxlet.2005.08.006⟩
Toxicology Letters, Elsevier, 2006, 161 (1), pp.61-72. ⟨10.1016/j.toxlet.2005.08.006⟩
Toxicology Letters, 2006, 161 (1), pp.61-72. ⟨10.1016/j.toxlet.2005.08.006⟩
Toxicology Letters, Elsevier, 2006, 161 (1), pp.61-72. ⟨10.1016/j.toxlet.2005.08.006⟩
International audience; Phenobarbital (PB) alters expression of numerous hepatic genes, including genes of cytochrome P450 2B1 and 2B2 (CYP2B). However, the intracellular mechanisms remain to be fully elucidated. The present study investigated the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27fdb40cfe33cd90a7be521a6d8a061
https://hal.science/hal-00699951
https://hal.science/hal-00699951
Publikováno v:
Acta cientifica venezolana. 53(1)
The fomesafen and 2,4-D amine herbicide induce cytotoxic effects at hepatic level in rats, such as: hepatomegaly, hyperplasia and increase in the enzymes activity which participate in the processes of peroxisomal beta-oxidation of fatty acids. In thi