The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children with Type 1 Diabetes

Autor: the Bionic Pancreas Research Group, Nelly Mauras, Keisha Bird, Peter Calhoun, Ryan Bailey, Viral N. Shah, Roy W. Beck, Edward R. Damiano, Steven J. Russell, Luz E. Castellanos

Objective: We evaluated the performance of the iLet® bionic pancreas (BP) in non-Hispanic Whites (‘Whites’) and in Blacks, Hispanics, and others (‘Minorities’). Research Design and Methods: A multicenter, randomized controlled trial evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bd85b07d796f5526459648b7a2dc17
https://doi.org/10.2337/figshare.22221280

Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes

Autor: Steven J, Russell, Roy W, Beck, Edward R, Damiano, Firas H, El-Khatib, Katrina J, Ruedy, Courtney A, Balliro, Zoey, Li, Peter, Calhoun, R Paul, Wadwa, Bruce, Buckingham, Keren, Zhou, Mark, Daniels, Philip, Raskin, Perrin C, White, Jane, Lynch, Jeremy, Pettus, Irl B, Hirsch, Robin, Goland, John B, Buse, Davida, Kruger, Nelly, Mauras, Andrew, Muir, Janet B, McGill, Fran, Cogen, Jill, Weissberg-Benchell, Jordan S, Sherwood, Luz E, Castellanos, Mallory A, Hillard, Marwa, Tuffaha, Melissa S, Putman, Mollie Y, Sands, Gregory, Forlenza, Robert, Slover, Laurel H, Messer, Erin, Cobry, Viral N, Shah, Sarit, Polsky, Rayhan, Lal, Laya, Ekhlaspour, Michael S, Hughes, Marina, Basina, Betul, Hatipoglu, Leann, Olansky, Amrit, Bhangoo, Nikta, Forghani, Himala, Kashmiri, Francoise, Sutton, Abha, Choudhary, Jimmy, Penn, Rabab, Jafri, Maria, Rayas, Elia, Escaname, Catherine, Kerr, Ruby, Favela-Prezas, Schafer, Boeder, Subbulaxmi, Trikudanathan, Kristen M, Williams, Natasha, Leibel, M Sue, Kirkman, Kate, Bergamo, Klara R, Klein, Jean M, Dostou, Sriram, Machineni, Laura A, Young, Jamie C, Diner, Arti, Bhan, J Kimberly, Jones, Matthew, Benson, Keisha, Bird, Kimberly, Englert, Joe, Permuy, Kristina, Cossen, Eric, Felner, Maamoun, Salam, Julie M, Silverstein, Samantha, Adamson, Andrea, Cedeno, Seema, Meighan, Carol, Wysham

Publikováno v: The New England journal of medicine. 387(13)

Currently available semiautomated insulin-delivery systems require individualized insulin regimens for the initialization of therapy and meal doses based on carbohydrate counting for routine operation. In contrast, the bionic pancreas is initialized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8176300ea04bd513d06ebac48976b050
https://pubmed.ncbi.nlm.nih.gov/36170505

Performance of the Insulin-Only iLet Bionic Pancreas and the Bihormonal iLet Using Dasiglucagon in Adults With Type 1 Diabetes in a Home-Use Setting

Autor: Courtney A. Balliro, Edward R. Damiano, Jordan Sherwood, Mallory A. Hillard, El-Khatib Firas H, Luz E. Castellanos, Evelyn Greaux, Steven Russell, Rabab Z. Jafri, Hui Zheng, Rajendranath Selagamsetty

Publikováno v: Diabetes Care

Reductions in blood glucose levels in people with diabetes are often achieved at the expense of increased hypoglycemia. A novel approach is to automatically deliver microdose glucagon when automation of insulin delivery alone is not sufficient to pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6e8f7391460db6b0713ba3ff6fccae
https://doi.org/10.2337/dc20-1086

216-OR: A Random-Order, Double-Blinded, Placebo-Controlled Study of the Bionic Pancreas in the Bihormonal vs. Insulin-Only Configurations Using Two Different Glucose Targets in Adults with Type 1 Diabetes in the Home-Use Setting

Autor: Marwa Tuffaha, Courtney A. Balliro, Luz E. Castellanos, Steven Russell, Jordan Sherwood, Edward R. Damiano, El-Khatib Firas H, Rajendranath Selagamsetty, Mallory A. Hillard

Publikováno v: Diabetes. 70

Objective: We evaluated the glycemic outcomes with 2 glucose targets in both configurations (bihormonal and insulin-only) of the bionic pancreas (BP) in a home-use study of adults with type 1 diabetes. Research Design and Methods: 20 participants com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2065305e2339aeaa26ec13ec31eae85a
https://doi.org/10.2337/db21-216-or

The epidemiology and management patterns of pediatric pituitary tumors in the United States

Autor: Timothy R. Smith, Edward R. Laws, J. Bryan Iorgulescu, Luz E. Castellanos, Madhusmita Misra

Publikováno v: Pituitary

PURPOSE: Hypothalamic-pituitary axis dysfunction and mass effect symptoms in the pediatric population can indicate a pituitary region tumor. Herein, we evaluate the epidemiology and management of this rare entity. METHODS: Pediatric patients (≤ 21y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e64e530aefe731c09aeb456384f85e2
https://europepmc.org/articles/PMC8415131/