Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Luz A. Knauer"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102141- (2023)
Summary: Here we detail a protocol for the isolation and processing of lymphatic enriched tissue of mouse models for the purpose of immunostaining and quantification of lymphatic valves, vessel length, and vessel diameter. Furthermore, we describe an
Externí odkaz:
https://doaj.org/article/2a1db6eaf7f3491c8f14c2380d588108
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Mutations in many genes that regulate lymphatic valve development are associated with congenital lymphedema. Oscillatory shear stress (OSS) from lymph provides constant signals for the growth and maintenance of valve cells throughout life. The expres
Externí odkaz:
https://doaj.org/article/d06811de0cc9451d984940db5d12c3b1
Autor:
Joshua P. Scallan, Jorge A. Castorena-Gonzalez, Michael J. Davis, Luz A. Knauer, Huayan Hou, Ying Yang
Publikováno v:
J Clin Invest
Patients with congenital lymphedema suffer from tissue swelling in part due to mutations in genes regulating lymphatic valve development. Lymphatic valve leaflets grow and are maintained throughout life in response to oscillatory shear stress (OSS),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0306a6a4bf76859d43edccd06f721d9
https://doi.org/10.1172/jci142341
https://doi.org/10.1172/jci142341