Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Luyuan Chang"'
A Multicenter Cohort Study on DNA Methylation for Endometrial Cancer Detection in Cervical Scrapings
Autor:
Xiao Ma, Xiaojun Chen, Jing Liang, Jingbo Zhang, Qixi Wu, Dong Wang, Xianghua Huang, Dan Zi, Dexin Chen, Hua Wan, Li Qu, Zhaoyun Jiang, Wenyu Shao, Jie Sun, Luyuan Chang, Yunchao Liu, Qin Zhang, Yanan Li, Yani Ding, Biao Tang, Fang Zhao, Hanqing Zhao, Dongyan Cao
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Background The increasing incidence of endometrial cancer (EC) has highlighted the need for improved early detection methods. This study aimed to develop and validate a novel DNA methylation classifier, EMPap, for EC detection using cervical
Externí odkaz:
https://doaj.org/article/965cb8dda3b240e8908593d19c7cf87c
Autor:
Yu Xiao, Wan Jin, Kaiyu Qian, Lingao Ju, Gang Wang, Kai Wu, Rui Cao, Luyuan Chang, Zilin Xu, Jun Luo, Liuying Shan, Fang Yu, Xintong Chen, Dongmei Liu, Hong Cao, Yejinpeng Wang, Xinyue Cao, Wei Zhou, Diansheng Cui, Ye Tian, Chundong Ji, Yongwen Luo, Xin Hong, Fangjin Chen, Minsheng Peng, Yi Zhang, Xinghuan Wang
Publikováno v:
Advanced Science, Vol 11, Iss 24, Pp n/a-n/a (2024)
Abstract Intratumor heterogeneity (ITH) of bladder cancer (BLCA) contributes to therapy resistance and immune evasion affecting clinical prognosis. The molecular and cellular mechanisms contributing to BLCA ITH generation remain elusive. It is found
Externí odkaz:
https://doaj.org/article/8d63530cd5a44bdf958db4470d19fd9e
Autor:
Weidong Yang, Pan He, Luyuan Chang, Tianshui Li, Xiaotian Bai, Zhiguo Luo, Nannan Zhao, Qingkuan Liu
Publikováno v:
Metals, Vol 13, Iss 12, p 1943 (2023)
Argon injection is usually applied in the continuous casting mold to prevent submerged entry nozzle (SEN) clogging. However, the stability of the slag–steel interface is affected by the injected gas, even leading to the formation of the slag eye. A
Externí odkaz:
https://doaj.org/article/4739427836824680be16628ec56378d5
Autor:
Yu Xiao, Lingao Ju, Kaiyu Qian, Wan Jin, Gang Wang, Yan Zhao, Wei Jiang, Nan Liu, Kai Wu, Minsheng Peng, Rui Cao, Sheng Li, Hongjie Shi, Yan Gong, Hang Zheng, Tongzu Liu, Yongwen Luo, Haoli Ma, Luyuan Chang, Gang Li, Xinyue Cao, Ye Tian, Zilin Xu, Zhonghua Yang, Liuying Shan, Zhongqiang Guo, Dongai Yao, Xianlong Zhou, Xintong Chen, Zicheng Guo, Dongmei Liu, Song Xu, Chundong Ji, Fang Yu, Xin Hong, Jun Luo, Hong Cao, Yi Zhang, Xinghuan Wang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Abstract Background State‐of‐art non‐invasive diagnosis processes for bladder cancer (BLCA) harbour shortcomings such as low sensitivity and specificity, unable to distinguish between high‐ (HG) and low‐grade (LG) tumours, as well as inabil
Externí odkaz:
https://doaj.org/article/b66ddbe85633434dbd59240bf619048a
Autor:
Juan Yu, Chaoyang Xiong, Baowen Zhuo, Zengqi Wen, Jie Shen, Cuifang Liu, Luyuan Chang, Kehui Wang, Min Wang, Chenyi Wu, Xudong Wu, Xueqin Xu, Haihe Ruan, Guohong Li
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107953- (2020)
Summary: Chromatin dynamics play a critical role in cell fate determination and maintenance by regulating the expression of genes essential for development and differentiation. In mouse embryonic stem cells (mESCs), maintenance of pluripotency coinci
Externí odkaz:
https://doaj.org/article/535649a3840e43bc8bcee137095351da
Autor:
Yan Wang, Haizhen Long, Juan Yu, Liping Dong, Michel Wassef, Baowen Zhuo, Xia Li, Jicheng Zhao, Min Wang, Cuifang Liu, Zengqi Wen, Luyuan Chang, Ping Chen, Qian-fei Wang, Xueqing Xu, Raphael Margueron, Guohong Li
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background The hierarchical organization of eukaryotic chromatin plays a central role in gene regulation, by controlling the extent to which the transcription machinery can access DNA. The histone variants H3.3 and H2A.Z have recently been i
Externí odkaz:
https://doaj.org/article/9bcdce8575f142c6ade14220a178e71e
Autor:
Wenjun Huang, Tiantian Zhang, Xudong Wu, Aoqun Song, Jicheng Zhao, Bing Zhu, Juan Yu, Min Wang, Cuifang Liu, Luyuan Chang, Xiaohua Shen, Guohong Li
Publikováno v:
Nature Cell Biology. 22:439-452
Stable propagation of epigenetic information is important for maintaining cell identity in multicellular organisms. However, it remains largely unknown how mono-ubiquitinated histone H2A on lysine 119 (H2AK119ub1) is established and stably propagated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a2e401d8dc5ab390560cdf8477dd69
https://doi.org/10.1038/s41556-020-0484-1
https://doi.org/10.1038/s41556-020-0484-1
Autor:
Wen-Hao Zhang, Haizhen Long, Xiulan Chen, Xi Wang, Peitao Zhang, Luyuan Chang, Zengqi Wen, Fuquan Yang, Jianfeng Pei, Mingzhao Zhu, Ping Chen, Raphaël Margueron, Liwei Zhang, Tongqing Li, Haiteng Deng, Guozhao Wu, Caiwei Jin, Mengjie Lv, Guohong Li
Publikováno v:
Nature. 577:576-581
DNA replication is a tightly regulated process that ensures the precise duplication of the genome during the cell cycle1. In eukaryotes, the licensing and activation of replication origins are regulated by both DNA sequence and chromatin features2. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddfd51ec4a0105f8b3052ee9f72ba89
https://doi.org/10.1038/s41586-019-1877-9
https://doi.org/10.1038/s41586-019-1877-9
Autor:
Yu Xiao, Wan Jin, Kaiyu Qian, Kai Wu, Gang Wang, Wei Jiang, Rui Cao, Lingao Ju, Yan Zhao, Hang Zheng, Tongzu Liu, Luyuan Chang, Zilin Xu, Ting Wang, Jun Luo, Liuying Shan, Fang Yu, Xintong Chen, Dongmei Liu, Hong Cao, Zhonghua Yang, Sheng Li, Hongjie Shi, Zhongqiang Guo, Yan Gong, Nan Liu, Shenjuan Li, Yejinpeng Wang, Xinyue Cao, Wenjun Ding, Wei Zhou, Diansheng Cui, Ye Tian, Chundong Ji, Yongwen Luo, Xin Hong, Haoli Ma, Fangjin Chen, Minsheng Peng, Yi Zhang, Xinghuan Wang
Intratumor heterogeneity (ITH) of bladder cancer (BLCA) facilitates therapy resistance and immune evasion to affect clinical prognosis directly. However, the molecular and cellular mechanism generating ITH in BLCA remains elusive. Here we show that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64309818eda148be0d58d1e1f5d0797d
https://doi.org/10.1101/2021.10.30.466556
https://doi.org/10.1101/2021.10.30.466556
Autor:
Wei He, Yuan Wei, Xiaoli Gong, Luyuan Chang, Wan Jin, Ke Liu, Xinghuan Wang, Yu Xiao, Wenjing Zhang, Qiong Chen, Kai Wu, Lili Liang, Jia Liu, Yawen Chen, Huanhuan Guo, Wenhao Chen, Jiexia Yang, Yiming Qi, Wei Dong, Meng Fu, Xiaojuan Li, Jiusi Liu, Yi Zhang, Aihua Yin
SummaryPreeclampsia, a life-threatening pregnancy complication characterized by hypertension and multiorgan damage, affects 2-5% of pregnancies and causes 76,000 deaths per year. Most preeclampsia associated syndromes immediately dispel after removal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61edb5eb97f987e7e0f76aa1f1057a37
https://doi.org/10.1101/2020.05.08.085290
https://doi.org/10.1101/2020.05.08.085290