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Nongenetic Factors Associated With Psychotic Experiences Among UK Biobank Participants: Exposome-Wide Analysis and Mendelian Randomization Analysis

Autor: Lin, B.D., Pries, L.K., Sarac, H.S., van Os, J., Rutten, B.P.F., Luykx, J., Guloksuz, S.

Publikováno v: JAMA Psychiatry, 79(9), 857-868. American Medical Association

IMPORTANCE Although hypothesis-driven research has identified several factors associated with psychosis, this one-exposure-to-one-outcome approach fails to embrace the multiplicity of exposures. Systematic approaches, similar to agnostic genome-wide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7424b0c5a2eab3da986051942812c4ce
https://pubmed.ncbi.nlm.nih.gov/35857297

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Akademický článek

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Akademický článek

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Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Autor: Wani A; University of South Florida College of Public Health, Genomics Program., Katrinli S; Emory University Department of Gynecology and Obstetrics., Zhao X; Boston University School of Public Health., Daskalakis N; Broad Institute of MIT and Harvard, Stanley Center for Psychiatric Research., Zannas A; University of North Carolina at Chapel Hill, Carolina Stress Initiative., Aiello A; Robert N Butler Columbia Aging Center, Columbia University., Baker D; University of California San Diego, Department of Psychiatry., Boks M; Brain Center University Medical Center Utrecht, Department of Psychiatry., Brick L; Alpert University, Brown University., Chen CY; Biogen Inc., Translational Sciences., Dalvie S; University of Cape Town, Department of Pathology., Fortier C; Harvard Medical School, Department of Psychiatry., Geuze E; Netherlands Ministry of Defence, Brain Research and Innovation Centre., Hayes J; The Ohio State University, Department of Psychology., Kessler R; Harvard Medical School, Department of Health Care Policy., King A; The Ohio State University, College of Medicine, Institute for Behavioral Medicine Research., Koen N; University of Cape Town, Department of Psychiatry & Mental Health., Liberzon I; Texas A&M University College of Medicine, Department of Psychiatry and Behavioral Sciences., Lori A; Emory University, Department of Psychiatry and Behavioral Sciences., Luykx J; UMC Utrecht Brain Center Rudolf Magnus, Department of Psychiatry., Maihofer A; University of California, San Diego., Milberg W; VA Boston Healthcare System, TRACTS/GRECC., Miller M; Boston University School of Medicine, Psychiatry., Mufford M; University of Cape Town, Neuroscience Institute., Nugent N; Alpert Brown Medical School, Department of Emergency Medicine., Rauch S; Emory University, Department of Psychiatry & Behavioral Sciences., Ressler K; Harvard Medical School, Department of Psychiatry., Risbrough V; University of California San Diego, Department of Psychiatry., Rutten B; Maastricht Universitair Medisch Centrum, School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology., Stein D; University of Cape Town, Department of Psychiatry & Mental Health., Stein M; University of California San Diego, Department of Psychiatry., Ursano R; Uniformed Services University, Department of Psychiatry., Verfaellie M; Boston University School of Medicine, Psychiatry., Ware E; University of Michigan, Population Studies Center., Wildman D; University of South Florida College of Public Health, Genomics Program., Wolf E; VA Boston Healthcare System, National Center for PTSD., Nievergelt C; University of California San Diego, Department of Psychiatry., Logue M; Boston University School of Public Health., Smith A; Emory University Department of Gynecology and Obstetrics., Uddin M; University of South Florida College of Public Health, Genomics Program., Vermetten E; Leiden University Medical Center, Department of Psychiatry., Vinkers C; Amsterdam Neuroscience, Mood, Anxiety, Psychosis, Sleep & Stress Program.

Publikováno v: Research square [Res Sq] 2024 Feb 15. Date of Electronic Publication: 2024 Feb 15.

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Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders

Autor: Okhuijsen-Pfeifer, C., van der Horst, M. Z., Bousman, C. A., Lin, B., van Eijk, K. R., Ripke, S., Ayhan, Y., Babaoglu, M. O., Bak, M., Alink, W., van Beek, H., Beld, E., Bouhuis, A., Edlinger, M., Erdogan, I. M., Ertuğrul, A., Yoca, G., Everall, I. P., Görlitz, T., van Amelsvoort, T., Bartels-Velthuis, A. A., Bruggeman, R., Cahn, W., Guloksuz, S., de Haan, L., Kahn, R. S., Schirmbeck, F., Simons, C. J. P., van Os, J., Alizadeh, B. Z., Luykx, J. J., Rutten, B. P. F., van Winkel, R., Grootens, K. P., Gutwinski, S., Hallikainen, T., Jeger-Land, E., de Koning, M., Lähteenvuo, M., Legge, S. E., Leucht, S., Morgenroth, C., Müderrisoğlu, A., Narang, A., Pantelis, C., Pardiñas, A. F., Oviedo-Salcedo, T., Schneider-Thoma, J., Schreiter, S., Repo-Tiihonen, E., Tuppurainen, H., Veereschild, M., Veerman, S., de Vos, M., Wagner, E., Cohen, D., Bogers, J. P. A. M., Walters, J. T. R., Yağcıoğlu, A. E. Anil, Tiihonen, J., Hasan, A.

Publikováno v: Translational Psychiatry, 12(1):145. Nature Publishing Group
Translational psychiatry, 12(1):145. Nature Publishing Group

Clozapine is the most effective antipsychotic for patients with treatment-resistant schizophrenia. However, response is highly variable and possible genetic underpinnings of this variability remain unknown. Here, we performed polygenic risk score (PR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d35979803fbaf570d9245558fcc0da
https://research.rug.nl/en/publications/68c11f0b-1d30-47b1-b8cc-469ae7b6003c

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Wat kunnen ggz-professionals doen om duurzaamheid te stimuleren?

Autor: Luykx, J. J., Tijdink, J. K., Krudop, W. A.

Publikováno v: Luykx, J J, Tijdink, J K & Krudop, W A 2022, ' Wat kunnen ggz-professionals doen om duurzaamheid te stimuleren? ', Tijdschrift voor Psychiatrie, vol. 64, no. 6, pp. 340-343 .
Tijdschrift voor Psychiatrie, 64(6), 340-343. Uitgeverij Boom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e81a650690750e608185a461bcd6c5fd
https://research.vumc.nl/en/publications/5ce13c25-7a5a-4a82-83c5-5138bd389b00

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Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings

Autor: Velthorst E., Mollon J., Murray R. M., de Haan L., Germeys I. M., Glahn D. C., Arango C., van der Ven E., Di Forti M., Bernardo M., Guloksuz S., Delespaul P., Mezquida G., Amoretti S., Bobes J., Saiz P. A., Garcia-Portilla M. P., Santos J. L., Jimenez-Lopez E., Sanjuan J., Aguilar E. J., Arrojo M., Carracedo A., Lopez G., Gonzalez-Penas J., Parellada M., Atbasoglu C., Saka M. C., Ucok A., Alptekin K., Akdede B., Binbay T., Altinyazar V., Ulas H., Yalincetin B., Gumus-Akay G., Beyaz B. C., Soygur H., Cankurtaran E. S., Kaymak S. U., Maric N. P., Mihaljevic M. M., Petrovic S. A., Mirjanic T., Del-Ben C. M., Ferraro L., Gayer-Anderson C., Jones P. B., Jongsma H. E., Kirkbride J. B., La Cascia C., Lasalvia A., Tosato S., Llorca P. -M., Menezes P. R., Morgan C., Quattrone D., Menchetti M., Selten J. -P., Szoke A., Tarricone I., Tortelli A., McGuire P., Valmaggia L., Kempton M. J., van der Gaag M., Riecher-Rossler A., Bressan R. A., Barrantes-Vidal N., Nelson B., McGorry P., Pantelis C., Krebs M. -O., Ruhrmann S., Sachs G., Rutten B. P. F., van Os J., Alizadeh B. Z., van Amelsvoort T., Bartels-Velthuis A. A., Bruggeman R., van Beveren N. J., Luykx J. J., Cahn W., Simons C. J. P., Kahn R. S., Schirmbeck F., van Winkel R., Calem M., Tognin S., Modinos G., Pisani S., Kraan T. C., van Dam D. S., Burger N., Amminger G. P., Politis A., Goodall J., Borgwardt S., Studerus E., Gadelha A., Brietzke E., Asevedo G., Asevedo E., Zugman A., Dominguez-Martinez T., Monsonet M., Cristobal-Narvaez P., Racioppi A., Kwapil T. R., Kazes M., Daban C., Bourgin J., Gay O., Mam-Lam-Fook C., Nordholm D., Rander L., Krakauer K., Glenthoj L. B., Glenthoj B., Gebhard D., Arnhold J., Klosterkotter J., Lasser I., Winklbaur B., Reichenberg A.

Publikováno v: EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, no. 8, pp. 4529-4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular Psychiatry, 26(8), 4529-4543. Nature Publishing Group
Scopus
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Molecular Psychiatry, 26, 4529-4543. Nature Publishing Group
Velthorst, E, Mollon, J, Murray, R M, de Haan, L, Germeys, I M, Glahn, D C, Arango, C, van der Ven, E, Di Forti, M, Bernardo, M, Guloksuz, S, Delespaul, P, Mezquida, G, Amoretti, S, Bobes, J, Saiz, P A, García-Portilla, M P, Santos, J L, Jiménez-López, E, Sanjuan, J, Aguilar, E J, Arrojo, M, Carracedo, A, López, G, González-Peñas, J, Parellada, M, Atbaşoğlu, C, Saka, M C, Üçok, A, Alptekin, K, Akdede, B, Binbay, T, Altınyazar, V, Ulaş, H, Yalınçetin, B, Gümüş-Akay, G, Beyaz, B C, Soygür, H, Cankurtaran, E Ş, Kaymak, S U, Maric, N P, Mihaljevic, M M, Petrovic, S A, Mirjanic, T, Del-Ben, C M, Ferraro, L, Gayer-Anderson, C, Jones, P B, Nordholm, D, Glenthøj, B & EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, pp. 4529–4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular psychiatry, 26(8), 4529-4543. Nature Publishing Group

The European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010-241909 (EUGEI); The Spanish sample was supported by the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III (SAM16PE07CP1, PI16/0201

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d9e628ae4c6e11e0cd469c1f89b6b4
https://doi.org/10.1038/s41380-020-00969-z

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