Výsledky vyhledávání - "Luyanda L.I. Kwofie"

Akademický článek

Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recovery of CD27, CD28, CD40, CD80, ICOS and GITR and substantially increased levels of PD-L1, LAG-3 and TIM-3

Autor: Bernardo L. Rapoport, Helen C. Steel, Carol A. Benn, Simon Nayler, Teresa Smit, Liezl Heyman, Annette J. Theron, Nomsa Hlatshwayo, Luyanda L.I. Kwofie, Pieter W.A. Meyer, Ronald Anderson

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

Neoadjuvant chemotherapy (NAC) may alter the immune landscape of patients with early breast cancer (BC), potentially setting the scene for more effective implementation of checkpoint-targeted immunotherapy. This issue has been investigated in the cur

Externí odkaz: https://doaj.org/article/c0d832b8aaf346e1977b95024d31c946

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Akademický článek

Systemic levels of the soluble co-inhibitory immune checkpoints, CTLA-4, LAG-3, PD-1/PD-L1 and TIM-3 are markedly increased in basal cell carcinoma

Autor: Nonkululeko Z. Malinga, Shalete C. Siwele, Helen C. Steel, Luyanda L.I. Kwofie, Pieter W.A. Meyer, Teresa Smit, Ronald Anderson, Bernardo L. Rapoport, Mahlatse C.M. Kgokolo

Publikováno v: Translational Oncology, Vol 19, Iss , Pp 101384- (2022)

Although co-inhibitory immune checkpoint proteins are primarily involved in promoting cell-cell interactions that suppress adaptive immunity, especially tumor immunity, the soluble cell-free variants of these molecules are also detectable in the circ

Externí odkaz: https://doaj.org/article/38c1da13674446748fab0b7151658895

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