Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Luxian Lv"'
Autor:
Xi Su, Guanyu Wang, Senqi Liu, Jinming Li, Minglong Shao, Yongfeng Yang, Meng Song, Yong Han, Wenqiang Li, Luxian Lv
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Autophagy is crucial for synaptic plasticity and the architecture of dendritic spines. However, the role of autophagy in schizophrenia (SCZ) and the mechanisms through which it affects synaptic function remain unclear. In this study, we iden
Externí odkaz:
https://doaj.org/article/178f95fea53b4b059a0c66d43887f922
Autor:
Xiaojing Li, Xiujuan Wang, Yongfeng Yang, Jiahui Zhou, Xufei Wu, Jingyuan Zhao, Jianhong Zhang, Xiaoge Guo, Minglong Shao, Meng Song, Xi Su, Yong Han, Qing Liu, Tengfei Chen, Luwen Zhang, Bing Liu, Weihua Yue, Luxian Lv, Wenqiang Li
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Oxidative stress and neuroinflammation contribute to schizophrenia (SCZ) pathology and may influence treatment efficacy. Matrix metalloproteinase 9 (MMP9) is a critical molecular node mediating the interaction between oxidative stress and in
Externí odkaz:
https://doaj.org/article/88c74cfb7a6740dd9e84081bcd0fbc36
Autor:
Xiujuan Wang, Jiahui Zhou, Shuang Ding, Jianhong Zhang, Yiliang Liu, Ya Liu, Jingyuan Zhao, Han Shi, Qing Liu, Meng Song, Luxian Lv, Wenqiang Li, Yongfeng Yang
Publikováno v:
Brain Research Bulletin, Vol 217, Iss , Pp 111075- (2024)
Objectives: Neuregulin 1 (NRG1) is a risk gene for schizophrenia and involved in neurodevelopment and synaptic plasticity. Polymorphisms in NRG1 may affect psychotic symptoms in schizophrenia. This study investigated the effects of the single nucleot
Externí odkaz:
https://doaj.org/article/6a0432ecfb374596b5357c80b6ffe294
Autor:
Chaoyue Ding, Ang Li, Sangma Xie, Xiaohan Tian, Kunchi Li, Lingzhong Fan, Hao Yan, Jun Chen, Yunchun Chen, Huaning Wang, Hua Guo, Yongfeng Yang, Luxian Lv, Huiling Wang, Hongxing Zhang, Lin Lu, Dai Zhang, Zhanjun Zhang, Meng Wang, Tianzi Jiang, Bing Liu
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract To elucidate the brain‐wide information interactions that vary and contribute to individual differences in schizophrenia (SCZ), an information‐resolved method is employed to construct individual synergistic and redundant interaction matr
Externí odkaz:
https://doaj.org/article/5a62d50651614340bd5b1ffd1c21cd96
Publikováno v:
Brain Research Bulletin, Vol 210, Iss , Pp 110927- (2024)
Schizophrenia patients have abnormalities in white matter (WM) integrity in brain regions. S100B has been shown to be a marker protein for glial cells. The atypical antipsychotics have neuroprotective effects on the brain. It is not clear whether ant
Externí odkaz:
https://doaj.org/article/6636d3d1609644cda4aa19396ed1f038
Autor:
Yongfeng Yang, Xueyan Jin, Yongjiang Xue, Xue Li, Yi Chen, Ning Kang, Wei Yan, Peng Li, Xiaoge Guo, Binbin Luo, Yan Zhang, Qing Liu, Han Shi, Luwen Zhang, Xi Su, Bing Liu, Lin Lu, Luxian Lv, Wenqiang Li
Publikováno v:
NeuroImage: Clinical, Vol 42, Iss , Pp 103603- (2024)
Antipsychotic drug treatment for schizophrenia (SZ) can alter brain structure and function, but it is unclear if specific regional changes are associated with treatment outcome. Therefore, we examined the effects of antipsychotic drug treatment on re
Externí odkaz:
https://doaj.org/article/50675b9d9002429894c3497f37b1fdd8
Autor:
Zhaoxi Zhong, Yangpan Ou, Yunhui Chen, Ping Li, Han Shi, Dan Lv, Cuicui Jia, Tinghuizi Shang, Lei Sun, Ru Yang, Xiaoping Wang, Wenbin Guo, Luxian Lv
Publikováno v:
Brain and Behavior, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Neuroimaging studies have revealed the role of the right dorsolateral prefrontal cortex (DLPFC) in the neurobiological mechanism of obsessive–compulsive disorder (OCD). However, only a few studies have examined the functional co
Externí odkaz:
https://doaj.org/article/a551574aecb24dad9a690be14e513e40
Autor:
Peipei Yan, Huicong Liu, Tao Zhou, Pu Sun, Yilin Wang, Xibin Wang, Lin Zhang, Tian Wang, Jing Dong, Jiangli Zhu, Luxian Lv, Wenqiang Li, Shiqian Qi, Yinming Liang, Eryan Kong
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-15 (2022)
Abstract The dynamics of synaptic vesicles (SVs) within presynaptic domains are tightly controlled by synapsin1 phosphorylation; however, the mechanism underlying the anchoring of synapsin1 with F-actin or SVs is not yet fully understood. Here, we fo
Externí odkaz:
https://doaj.org/article/c3b9886e944140ff9a7d0effed82eda5
Autor:
Shiwu Li, Changguo Ma, Yifan Li, Rui Chen, Yixing Liu, Li Pear Wan, Qiuxia Xiong, Chuang Wang, Yongxia Huo, Xinglun Dang, Yongfeng Yang, Luxian Lv, Xi Chen, Nengyin Sheng, Wenqiang Li, Xiong-Jian Luo
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The missense variant rs13107325 (C/T, p.Ala391Thr) in SLC39A8 consistently showed robust association with schizophrenia in recent genome-wide association studies (GWASs), suggesting the potential pathogenicity of this non-synonymous risk var
Externí odkaz:
https://doaj.org/article/b00f5596114d497d98229245a2eff30e
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundObesity is a prevalent health problem in patients with schizophrenia, and calorie restriction diet (CRD) achieved effective weight loss and metabolic improvement; however, these have not been rigorously evaluated in obese patients with schi
Externí odkaz:
https://doaj.org/article/7225cbbb6f4340f28c65a1a2d6227496