Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Luwa Yuan"'
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 3, Iss , Pp 100123- (2022)
GPCR signaling and function depend on their associated proteins and subcellular locations. Besides G-proteins and β-arrestins, 14-3-3 proteins participate in GPCR trafficking and signaling, and they connect a large number of diverse proteins to form
Externí odkaz:
https://doaj.org/article/f2b3956c0dd046f89dca8b08a339af35
Autor:
Haifeng Eishingdrelo, Sathapana Kongsamut, Luwa Yuan, Shahar Barbash, Alex Eishingdrelo, Thomas P. Sakmar
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Receptor trafficking is pivotal for the temporal and spatial control of GPCR signaling and is regulated by multiple cellular proteins. We provide evidence that GPCRs interact with 14-3-3 signal adaptor/scaffold proteins and that this interaction regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fb5529acf0e8f43d8f9a046a0bac62
https://doi.org/10.1038/s41598-019-47478-w
https://doi.org/10.1038/s41598-019-47478-w
Autor:
Long Zhao, Qing Wang, Benjamin Tycko, Denise S. O'Keefe, Mark T. Keating, Naifeng Qian, Dale Frank, Colum P. Walsh, Diem Dao, Luwa Yuan
Publikováno v:
Human Molecular Genetics. 6:2021-2029
We searched for novel imprinted genes in a region of human chromosome 11p15.5, which contains several known imprinted genes. Here we describe the cloning and characterization of the IPL ( I mprinted in P lacenta and L iver) gene, which shows tissue-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e770d41ee885a4cd91684d99df2d095
https://doi.org/10.1093/hmg/6.12.2021
https://doi.org/10.1093/hmg/6.12.2021
Autor:
Wai-Yee Chung, Thomas A. Moulton, Pamela Waber, Benjamin Tycko, Terrence Hensle, Luwa Yuan, Perry Nisen
Publikováno v:
Medical and Pediatric Oncology. 27:476-483
The selective loss of maternal and reduplication of paternal chromosome 11p15.5 alleles in Wilms' tumors (WTs) points to the existence of a paternally imprinted tumor suppressor gene(s) and/or a maternally imprinted dose-dependent growth-promoting ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98df3a5126700ee2ffedaa1cd36737b
https://doi.org/10.1002/(sici)1096-911x(199611)27:5<476::aid-mpo15>3.0.co
https://doi.org/10.1002/(sici)1096-911x(199611)27:5<476::aid-mpo15>3.0.co
Publikováno v:
Human genetics. 112(4)
At least eight genes clustered in 1 Mb of DNA on human chromosome (Chr) 11p15.5 are subject to parental imprinting, with monoallelic expression in one or more tissues. Orthologues of these genes show conserved linkage and imprinting on distal Chr 7 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd268cc3e45405b972b1620289ed3ecb
https://pubmed.ncbi.nlm.nih.gov/12589428
https://pubmed.ncbi.nlm.nih.gov/12589428
Autor:
Benjamin Tycko, Colum P. Walsh, Perry Nisen, Terrence Hensle, Lin Feng, Luwa Yuan, Dmitri Gorelov, Diem Dao, Darrell J. Yamashiro, Timothy H. Bestor
Publikováno v:
Human molecular genetics. 8(7)
WT2 is defined by maternal-specific loss of heterozygosity (LOH) on chromosome 11p15.5 in Wilms' tumors (WTs). The imprinted H19 gene, in this region, is silenced and hypermethylated in most WTs, and this is linked to pathological biallelic expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739572f9d2035cd1795b7b24c57927c8
https://pubmed.ncbi.nlm.nih.gov/10369881
https://pubmed.ncbi.nlm.nih.gov/10369881
Publikováno v:
Human molecular genetics. 5(12)
There is increasing evidence for chromosomal domains containing multiple imprinted genes and for domain-wide disruption of imprinting in certain diseases. In a majority of Wilms' tumors (WTs) there is an abnormal bipaternal pattern of expression at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbed083300f02ccb6c26cf7c2c9a2bc
https://pubmed.ncbi.nlm.nih.gov/8968746
https://pubmed.ncbi.nlm.nih.gov/8968746
Publikováno v:
Human molecular genetics. 5(8)
The imprinted H19 gene is frequently inactivated in Wilms' tumors (WTs) either by chromosome 11p15.5 loss of heterozygosity (LOH) or by hypermethylation of the maternal allele and it is possible that there might be coordinate disruption of imprinting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665297390b39e65a3a332ae5953793d8
https://pubmed.ncbi.nlm.nih.gov/8842727
https://pubmed.ncbi.nlm.nih.gov/8842727
Autor:
Licia Selleri, Benjamin Tycko, Floria Lupu, Frédéric Gilles, Andrew D. Zelenetz, Andre Goye, Yu-Hung Kuo, Ghassan J. Samara, Patricia Tsang, Luwa Yuan, Josh Moosikasuwan
Publikováno v:
Human Molecular Genetics. 4:2187-2188
The closely linked IGF2 and H19 genes on human chromosome 11p15.5 are monoallelically expressed as a result of genomic imprinting and show altered expression in Wilms' tumors (WTs). To map regional imprinting we have sought to isolate additional huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9964c221639a193f1bc3c3d970e1e32b
https://doi.org/10.1093/hmg/4.11.2187
https://doi.org/10.1093/hmg/4.11.2187