Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Luu V Pham"'
Autor:
Michele L. Singer, Mi-Kyung Shin, Lenise J. Kim, Carla Freire, O Aung, Huy Pho, Joshua A. East, Frank P. Sgambati, Alban Latremoliere, Luu V. Pham, Vsevolod Y. Polotsky
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Opioid-induced respiratory depression (OIRD) is the primary cause of death associated with opioids and individuals with obesity are particularly susceptible due to comorbid obstructive sleep apnea (OSA). Repeated exposure to opioids, as
Externí odkaz:
https://doaj.org/article/9310a03d6f3d40429e3f98cf74eea5e0
Autor:
James J. Yu, Amy L. Non, Erica C. Heinrich, Wanjun Gu, Joe Alcock, Esteban A. Moya, Elijah S. Lawrence, Michael S. Tift, Katie A. O'Brien, Jay F. Storz, Anthony V. Signore, Jane I. Khudyakov, William K. Milsom, Sean M. Wilson, Cynthia M. Beall, Francisco C. Villafuerte, Tsering Stobdan, Colleen G. Julian, Lorna G. Moore, Mark M. Fuster, Jennifer A. Stokes, Richard Milner, John B. West, Jiao Zhang, John Y. Shyy, Ainash Childebayeva, José Pablo Vázquez-Medina, Luu V. Pham, Omar A. Mesarwi, James E. Hall, Zachary A. Cheviron, Jeremy Sieker, Arlin B. Blood, Jason X. Yuan, Graham R. Scott, Brinda K. Rana, Paul J. Ponganis, Atul Malhotra, Frank L. Powell, Tatum S. Simonson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The ability to respond rapidly to changes in oxygen tension is critical for many forms of life. Challenges to oxygen homeostasis, specifically in the contexts of evolutionary biology and biomedicine, provide important insights into mechanisms of hypo
Externí odkaz:
https://doaj.org/article/ad6281793d794d10a1e325e2249296a9
Autor:
Lenise J. Kim, Mi-Kyung Shin, Huy Pho, Laszlo Otvos, Sergio Tufik, Monica L. Andersen, Luu V. Pham, Vsevolod Y. Polotsky
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundObesity can cause hypertension and exacerbates sleep-disordered breathing (SDB). Leptin is an adipocyte-produced hormone, which increases metabolic rate, suppresses appetite, modulates control of breathing, and increases blood pressure. Obe
Externí odkaz:
https://doaj.org/article/654bed9a103c4c73901704080baeaddc
Autor:
Lenise J. Kim, Chloe Alexandre, Huy Pho, Alban Latremoliere, Vsevolod Y. Polotsky, Luu V. Pham
Publikováno v:
Journal of Applied Physiology. 133:1284-1294
Obesity is associated with sleep-disordered breathing (SDB) and unrefreshing sleep. Residual daytime sleepiness and sleep impairments often persist after SDB treatment in patients with obesity, which suggests an independent effect of obesity on breat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c6f6d2cd0341b3e70fcbac2927afdb
https://doi.org/10.1152/japplphysiol.00386.2022
https://doi.org/10.1152/japplphysiol.00386.2022
Autor:
Lenise J. Kim, Mi‐Kyung Shin, Huy Pho, Wan‐Yee Tang, Nishitha Hosamane, Frederick Anokye‐Danso, Rexford S. Ahima, James S. K. Sham, Luu V. Pham, Vsevolod Y. Polotsky
Publikováno v:
The Journal of Physiology. 600:5145-5162
Sleep-disordered breathing (SDB) affects over 50% of obese individuals. Exaggerated hypoxic chemoreflex is a cardinal trait of SDB in obesity. We have shown that leptin acts in the carotid bodies (CB) to augment chemoreflex and that leptin activates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508d20f8f526ba2b2880c94802fb8af8
https://doi.org/10.1113/jp283678
https://doi.org/10.1113/jp283678
Autor:
Ana Sanchez-Azofra, Francisco C. Villafuerte, Pamela N. DeYoung, Dillon Gilbertson, Wanjun Gu, Esteban A. Moya, Gustavo Vizcardo-Galindo, Rómulo Figueroa-Mujíca, Cecilia Anza-Ramirez, Jose L. Macarlupú, Luu V. Pham, Peter Wagner, Atul Malhotra, Tatum S. Simonson, Omar A. Mesarwi
Publikováno v:
Journal of Clinical Sleep Medicine. 18:2423-2432
STUDY OBJECTIVES: Chronic mountain sickness (CMS) is commonly observed among Andean and other highland populations. Sleep-disordered breathing (SDB) is highly prevalent at high altitude, and SDB and nocturnal hypoxemia have been observed in CMS. Phle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8334d042ebae67fe76593c200c0002b2
https://doi.org/10.5664/jcsm.10136
https://doi.org/10.5664/jcsm.10136
Autor:
Adam Osman, Chenjuan Gu, David E. Kim, Daisy Duan, Bobbie Barron, Luu V. Pham, Vsevolod Y. Polotsky, Jonathan C. Jun
Publikováno v:
Respirology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46ad1ddbb7ed4f8229edd4d3fba6f220
https://doi.org/10.1111/resp.14526
https://doi.org/10.1111/resp.14526
Autor:
Alan R. Schwartz, Ofer Jacobowitz, David W. Eisele, Samuel A. Mickelson, Mitchell B. Miller, Arie Oliven, Victor Certal, Martin L. Hopp, David H. Winslow, Tod C. Huntley, Nathan E. Nachlas, Luu V. Pham, M. Boyd Gillespie, Brian H. Weeks, Eric G. Lovett, John Shen, Atul Malhotra, Joachim T. Maurer
Publikováno v:
JAMA Otolaryngology–Head & Neck Surgery.
ImportanceEvidence is lacking from randomized clinical trials of hypoglossal nerve stimulation in obstructive sleep apnea (OSA).ObjectiveTo evaluate the safety and effectiveness of targeted hypoglossal nerve stimulation (THN) of the proximal hypoglos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faddfe9f57db32721b3dd3bf94ba3227
https://doi.org/10.1001/jamaoto.2023.0161
https://doi.org/10.1001/jamaoto.2023.0161
Autor:
Lenise J. Kim, Mi-Kyung Shin, Huy Pho, Laszlo Otvos, Sergio Tufik, Monica L. Andersen, Luu V. Pham, Vsevolod Y. Polotsky
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
BackgroundObesity can cause hypertension and exacerbates sleep-disordered breathing (SDB). Leptin is an adipocyte-produced hormone, which increases metabolic rate, suppresses appetite, modulates control of breathing, and increases blood pressure. Obe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baaceef947faae7cb6a892a0c012683
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Background: Obstructive sleep apnea (OSA) and nocturnal hypoxia are associated with disturbances in glucose regulation and diabetes. Temporal associations between OSA, oxygenation profiles and glucose have not been well-described. We hypothesized tha
Externí odkaz:
https://doaj.org/article/8b487e0c5cca4c078abc0d5365258fd3