Proteomic Assessment of Extracellular Vesicles from Canine Tissue Explants as a Pipeline to Identify Molecular Targets in Osteosarcoma: PSMD14/Rpn11 as a Proof of Principle.

Autor: Luu AK; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Cadieux M; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Wong M; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Macdonald R; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Jones R; Department of Animal Biosciences, Ontario Agricultural College, University of Guelph, Guelph, ON N1G 2W1, Canada., Choi D; Department of Biochemistry, College of Medicine, Soonchunhyang University, Cheonan 31151, Korea., Oblak M; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Brisson B; Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Sauer S; Vuja De Sciences, Inc., Natick, MA 01760, USA., Chafitz J; SBH Sciences, Natick, MA 01760, USA., Warshawsky D; Vuja De Sciences, Inc., Natick, MA 01760, USA., Wood GA; Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Viloria-Petit AM; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Mar 17; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 17.

Targeting Mechanotransduction in Osteosarcoma: A Comparative Oncology Perspective.

Autor: Luu AK; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada., Viloria-Petit AM; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 14; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 14.

Extracellular matrix production and oxygen diffusion regulate chemotherapeutic response in osteosarcoma spheroids.

Autor: Sagheb, Isabel S.¹ (AUTHOR), Coonan, Thomas P.¹ (AUTHOR), Randall, R. Lor² (AUTHOR), Griffin, Katherine H.^2,3 (AUTHOR) khgriffin@ucdavis.edu, Leach, J. Kent^1,2 (AUTHOR) jkleach@ucdavis.edu

Publikováno v: Cancer Medicine. Sep2024, Vol. 13 Issue 18, p1-13. 13p.

An evaluation of TAZ and YAP crosstalk with TGFβ signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression.

Autor: Luu AK; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada., Schott CR; Department of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada., Jones R; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada., Poon AC; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada., Golding B; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada., Hamed R; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada., Deheshi B; Medical City Forth Worth, HCA affiliated Hospital, 900 8th Ave, Fort Worth, TX, 76104, USA., Mutsaers A; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada., Wood GA; Department of Pathobiology, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. gewood@uoguelph.ca., Viloria-Petit AM; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, N1G 2W1, Canada. aviloria@uoguelph.ca.

Publikováno v: BMC veterinary research [BMC Vet Res] 2018 Nov 26; Vol. 14 (1), pp. 365. Date of Electronic Publication: 2018 Nov 26.

Therapeutic trial of fluvastatin in a cell line xenograft model of canine mammary gland cancer.

Autor: Atmane, Mohamed Issam¹ (AUTHOR), Vigneau, Anne‐Laurence¹ (AUTHOR), Beaudry, Francis^2,3 (AUTHOR), Rico, Charlène² (AUTHOR), Boerboom, Derek^2,4 (AUTHOR), Paquet, Marilène^1,4 (AUTHOR) marilene.paquet@umontreal.ca

Publikováno v: Veterinary & Comparative Oncology. Dec2023, Vol. 21 Issue 4, p634-645. 12p.