Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lutz Sternfeld"'
Autor:
George Liu, Irene Schulz, Jorge A. Rodriguez, Michael R. Hayden, Fei Yang, Christopher A Ross, Yuhui Wang, Frédéric Carrière, Lutz Sternfeld
Publikováno v:
Acta Physiologica. 195:13-28
Aim and methods: Recurrent pancreatitis is a common complication of severe hypertriglyceridaemia (HTG) often seen in patients carrying various gene mutations in lipoprotein lipase (LPL). This study investigates a possible pathogenic mechanism of cell
Autor:
Werner Hofer, Irene Schulz, Lutz Sternfeld, Fei Yang, George Liu, Colin J. D. Ross, Michael R. Hayden, Yuhui Wang, Frédéric Carrière, Jorge A. Rodriguez
Publikováno v:
Gut. 58:422-430
Recurrent pancreatitis is a common complication of severe hypertriglyceridaemia in patients with various gene mutations in lipoprotein lipase (LPL) or apolipoprotein CII. However, the exact pathogenetic mechanism has not yet been defined.Susceptibili
Autor:
Andreas Schmid, Dietmar Schreiner, Elmar Krause, Lutz Sternfeld, Irene Schulz, Ines Anderie, Hajaj Al-Shaldi, Thomas Magg, Hans-Werner Hofer
Publikováno v:
Cell Calcium. 42:91-102
In HEK293 cells, transfected with the Ca2+ channel protein TRPV6, Ca2+ influx is increased and TRPV6 is tyrosine phosphorylated following addition of the tyrosine phosphatase inhibitor N,N-dimethyl-hydroxamido hydroxovanadate to cells. This effect of
Publikováno v:
Cellular Signalling. 19:1457-1464
In many cell types membrane receptors for hormones or neurotransmitters activate a signal transduction pathway which releases Ca 2+ from intracellular Ca 2+ stores by the second messenger inositol 1,4,5-trisphosphate. As a consequence store-operated
Autor:
Andreas Schmid, Irene Schulz, Ines Anderie, Hans Werner Hofer, Gonzalo P. Solis, Lutz Sternfeld, Shyuefang Hsu
Publikováno v:
Cellular Signalling. 15:1149-1156
We have studied modulation of "store-operated calcium influx" by tyrosine phosphatases in the pancreatic acinar cell line AR42J and in HEK 293 cells. We show that inhibition of tyrosine phosphatases by bis-(N,N-dimethyl-hydroxamido) hydrooxovanadate
Publikováno v:
Journal of Biological Chemistry. 276:16986-16991
In pancreatic acinar cells analysis of the propagation speed of secretagogue-evoked Ca2+ waves can be used to examine coupling of hormone receptors to intracellular signal cascades that cause activation of protein kinase C or production of arachidoni
Autor:
Elmar Krause, Lutz Sternfeld, Ginés M. Salido, Antonio González, Andreas Schmid, Irene Schulz
Publikováno v:
Biochemical and Biophysical Research Communications. 261:726-733
We employed confocal laser-scanning microscopy to monitor cholecystokinin (CCK)-evoked Ca(2+) signals in fluo-3-loaded mouse pancreatic acinar cells. CCK-8-induced Ca(2+) signals start at the luminal cell pole and subsequently spread toward the basol
Depletion of inositol 1,4,5 trisphosphate-sensitive Ca 2+ stores generates a yet unknown signal, which leads to increase in Ca 2+ influx in different cell types [J.W. Putney Jr., A model for receptor-regulated calcium entry, Cell Calcium 7 (1986) 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b74657af1d88d172af07b08dd75518
http://eprints.ugd.edu.mk/2200/
http://eprints.ugd.edu.mk/2200/
Publikováno v:
The Journal of biological chemistry. 278(36)
Cyclic ADP-ribose, a metabolite of NAD+ evokes Ca2+ release from intracellular stores in different cells. We have determined the activity of cADPr-producing enzymes (ADP-ribosyl cyclases) in different cellular fractions prepared from isolated pancrea
Publikováno v:
Archives of biochemistry and biophysics. 378(2)
In inflammatory cells, agonist-stimulated arachidonic acid (AA) release is thought to be induced by activation of group IV Ca(2+)-dependent cytosolic phospholipase A(2) (cPLA(2)) through mitogen-activated protein kinase (MAP kinase)- and/or protein k