Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Lutz Langbein"'
Autor:
Matthias Schäfer, Ann‐Helen Willrodt, Svitlana Kurinna, Andrea S Link, Hany Farwanah, Alexandra Geusau, Florian Gruber, Olivier Sorg, Aaron J Huebner, Dennis R Roop, Konrad Sandhoff, Jean‐Hilaire Saurat, Erwin Tschachler, Marlon R Schneider, Lutz Langbein, Wilhelm Bloch, Hans‐Dietmar Beer, Sabine Werner
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 4, Pp 442-457 (2014)
Abstract The transcription factor Nrf2 is a key regulator of the cellular stress response, and pharmacological Nrf2 activation is a promising strategy for skin protection and cancer prevention. We show here that prolonged Nrf2 activation in keratinoc
Externí odkaz:
https://doaj.org/article/8045fc2494be47d89d7a67ce26c7aaac
Autor:
Margot Zöller, Lutz Langbein, Markus Ladwein, Sebastian Kuhn, Tobias Weiss, Hüseyin Tuncay, Julia Preobraschenski, Tobias Nübel
EpCAM has been described as a therapeutically relevant tumor marker. We noted an interaction between EpCAM and the tight junction protein claudin-7 and here explored the nature of this interaction and its effect on EpCAM-mediated functions. The inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd37c13f04ea98b0037e870804808a9
https://doi.org/10.1158/1541-7786.c.6541957.v1
https://doi.org/10.1158/1541-7786.c.6541957.v1
Autor:
Margot Zöller, Jürgen Weitz, Werner W. Franke, Lutz Langbein, Gerhard Moldenhauer, Dagmar Hildebrand, Pamela Klingbeil, Dalibor Antolovic, Markus Ladwein, Tobias Nübel, Moritz Koch, Sebastian Kuhn
Supplementary Data from A Complex of EpCAM, Claudin-7, CD44 Variant Isoforms, and Tetraspanins Promotes Colorectal Cancer Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1158a48346438f48c1a002fb7ae424d2
https://doi.org/10.1158/1541-7786.22521090.v1
https://doi.org/10.1158/1541-7786.22521090.v1
Autor:
Margot Zöller, Lutz Langbein, Markus Ladwein, Sebastian Kuhn, Tobias Weiss, Hüseyin Tuncay, Julia Preobraschenski, Tobias Nübel
Supplementary Figures S1-S3 from Claudin-7 Regulates EpCAM-Mediated Functions in Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9ef79ea871f426ae5589f3e0602bdb
https://doi.org/10.1158/1541-7786.22518508
https://doi.org/10.1158/1541-7786.22518508
Autor:
Stephanie Patouraux, Damien Ambrosetti, Jürgen Schweizer, Lutz Langbein, G Cannata, Christophe Perrin
Publikováno v:
The American Journal of Dermatopathology. 39:40-44
The authors have recently proposed to use the name pachyonychia as an umbrella term that includes 2 distinctly different entities in the form of congenital pachyonychia and acquired longitudinal pachyonychia. Congenital pachyonychia is defined by a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b65c309ccd726729f8a11783cea2c8b
https://doi.org/10.1097/dad.0000000000000579
https://doi.org/10.1097/dad.0000000000000579
Autor:
Florian, Ehrlich, Heinz, Fischer, Lutz, Langbein, Silke, Praetzel-Wunder, Bettina, Ebner, Katarzyna, Figlak, Anton, Weissenbacher, Wolfgang, Sipos, Erwin, Tschachler, Leopold, Eckhart
Publikováno v:
Molecular biology and evolution. 36(2)
Keratins are the main intermediate filament proteins of epithelial cells. In keratinocytes of the mammalian epidermis they form a cytoskeleton that resists mechanical stress and thereby are essential for the function of the skin as a barrier against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1aa12e1f139e42a22f34ed532184ea9
https://pubmed.ncbi.nlm.nih.gov/30715442
https://pubmed.ncbi.nlm.nih.gov/30715442
Autor:
Heinz Fischer, Lutz Langbein, Erwin Tschachler, Julia Reichelt, Minoo Ghannadan, Leopold Eckhart, Silke Praetzel-Wunder, Maria Buchberger
Publikováno v:
Journal of Investigative Dermatology. 134(10):2579-2588
Keratin K2 is one of the most abundant structural proteins of the epidermis; however, its biological significance has remained elusive. Here we show that suprabasal type II keratins, K1 and K2, are expressed in a mutually exclusive manner at differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c7d5b3872f6d3779501ef2c027c7b9
Publikováno v:
Journal of Cutaneous Pathology. 41:427-436
Background Pilomatricomas are tumors that emulate the differentiation of matrix cells of the hair follicle, showing cortical differentiation, with sequential expression of K35 and K31 keratins. Beta-catenin gene is frequently mutated in pilomatricoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a224fd01d4d261cc03bda5d67b281c6a
https://doi.org/10.1111/cup.12313
https://doi.org/10.1111/cup.12313
Autor:
Christophe Perrin, Nouran Erfan, Damien Ambrossetti, Jürgen Schweizer, Lutz Langbein, Jean-François Michiels
Publikováno v:
The American Journal of Dermatopathology. 35:679-684
We have recently described a new nail tumor known as onychocytic matricoma. Herein, we describe its malignant counterpart. Clinically, the tumor simulates onychomatricoma (OM). Histologically, this in situ malignant epithelial tumor exhibits a distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e596f4c98c0dee1950ca851caae20c
https://doi.org/10.1097/dad.0b013e3182827fec
https://doi.org/10.1097/dad.0b013e3182827fec
Autor:
Richard Jennemann, Daniel Mathow, Norbert Gretz, Nicole Amen, Carsten Jäckel, Mariona Rabionet, Roger Sandhoff, Lutz Langbein, Hermann Josef Gröne
Publikováno v:
Human Molecular Genetics. 22:4164-4179
Skin barrier function is primarily assigned to the outer epidermal layer, the stratum corneum (SC), mainly composed of corneocytes and lipid-enriched extracellular matrix. Epidermal ceramides (Cers) are essential barrier lipids, containing ultra-long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d9c6ee6d20be1834cf4b088ede2369
https://doi.org/10.1093/hmg/ddt264
https://doi.org/10.1093/hmg/ddt264