Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lutz Kloke"'
Autor:
Rodrigo M. Florentino, Kazutoyo Morita, Nils Haep, Takashi Motomura, Ricardo Diaz-Aragon, Lanuza A.P. Faccioli, Alexandra Collin de l’Hortet, Zeliha Cetin, Carla Frau, Lawrence Vernetti, Anna-Klara Amler, Alexander Thomas, Tobias Lam, Lutz Kloke, Kazuki Takeishi, D. Lansing Taylor, Ira J. Fox, Alejandro Soto-Gutierrez
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105503- (2022)
Summary: Advances in cellular engineering, as well as gene, and cell therapy, may be used to produce human tissues with programmable genetically enhanced functions designed to model and/or treat specific diseases. Fabrication of synthetic human liver
Externí odkaz:
https://doaj.org/article/456852f3c07c4362a0ae4b0b01b19d89
Autor:
Anna-Klara Amler, Domenic Schlauch, Selin Tüzüner, Alexander Thomas, Norbert Neckel, Ingeborg Tinhofer, Max Heiland, Roland Lauster, Lutz Kloke, Carmen Stromberger, Susanne Nahles
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Radiotherapy of head and neck squamous cell carcinoma can lead to long-term complications like osteoradionecrosis, resulting in severe impairment of the jawbone. Current standard procedures require a 6-month wait after irradiation before den
Externí odkaz:
https://doaj.org/article/4796e467585e46808a71b4d930f1e3f5
Autor:
Anna-Klara Amler, Alexander Thomas, Selin Tüzüner, Tobias Lam, Michel-Andreas Geiger, Anna-Elisabeth Kreuder, Chris Palmer, Susanne Nahles, Roland Lauster, Lutz Kloke
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Jawbone differs from other bones in many aspects, including its developmental origin and the occurrence of jawbone-specific diseases like MRONJ (medication-related osteonecrosis of the jaw). Although there is a strong need, adequate in vitro
Externí odkaz:
https://doaj.org/article/a55c496c29ff4ecdb9bf2348d395f254
Autor:
Laura Grunewald, Tobias Lam, Lena Andersch, Anika Klaus, Silke Schwiebert, Annika Winkler, Anton Gauert, Anja I. Heeren-Hagemann, Kathy Astrahantseff, Filippos Klironomos, Alexander Thomas, Hedwig E. Deubzer, Anton G. Henssen, Angelika Eggert, Johannes H. Schulte, Kathleen Anders, Lutz Kloke, Annette Künkele
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chimeric antigen receptor (CAR) T cell performance against solid tumors in mouse models and clinical trials is often less effective than predicted by CAR construct selection in two-dimensional (2D) cocultures. Three-dimensional (3D) solid tumor archi
Externí odkaz:
https://doaj.org/article/36d3f87310c541579111c11eb4745bb7
Autor:
Robert Koban, Tobias Lam, Franziska Schwarz, Lutz Kloke, Silvio Bürge, Heinz Ellerbrok, Markus Neumann
Publikováno v:
Viruses, Vol 12, Iss 11, p 1298 (2020)
Studies of virus–host interactions in vitro may be hindered by biological characteristics of conventional monolayer cell cultures that differ from in vivo infection. Three-dimensional (3D) cell cultures show more in vivo-like characteristics and ma
Externí odkaz:
https://doaj.org/article/9bc11e0a675e445490146990f4a2c434
Autor:
Angelika Rose, Caroline von Spee-Mayer, Lutz Kloke, Kaiyin Wu, Anja Kühl, Philipp Enghard, Gerd-Rüdiger Burmester, Gabriela Riemekasten, Jens Y. Humrich
Publikováno v:
Cells, Vol 8, Iss 10, p 1234 (2019)
An acquired deficiency of interleukin-2 (IL-2) and related disturbances in regulatory T cell (Treg) homeostasis play an important role in the pathogenesis of systemic lupus erythematosus (SLE). Low-dose IL-2 therapy was shown to restore Treg homeosta
Externí odkaz:
https://doaj.org/article/6c6ebae72a8047be855d2126190e7c85
Autor:
Nina Hedemann, Alexander Thomas, Nils Tribian, Lutz Kloke, Dirk Bauerschlag, Marion van Mackelenbergh
Publikováno v:
Cancer Research. 83:P2-15
Although multi-modal and ablative treatment strategies for breast cancer are becoming more popular, partial or full mastectomy is still a most common intervention. While proving to be effective in curing the cancer, it leaves the patient disfigured,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc81086a85828bcec49535b8841b24b9
https://doi.org/10.1158/1538-7445.sabcs22-p2-15-06
https://doi.org/10.1158/1538-7445.sabcs22-p2-15-06
Autor:
Isabel Orellano, Alexander Thomas, Aaron Herrera, Erik Brauer, Dag Wulsten, Ansgar Petersen, Lutz Kloke, Georg N. Duda
Nutrient supply via a functional vasculature is essential during regenerative processes, tissue growth, and homeostasis. 3D bioprinting offers the opportunity to engineer vascularized constructs by combining cells and biocompatible materials in speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedd32775c057a5adcca29116bebae26
Autor:
Lennard K. Shopperly, Jacob Spinnen, Jan‐Philipp Krüger, Michaela Endres, Michael Sittinger, Tobias Lam, Lutz Kloke, Tilo Dehne
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterialsREFERENCES. 110(10)
Stereolithographic bioprinting holds great promise in the quest for creating artificial, biomimetic cartilage-like tissue. To introduce a more biomimetic approach, we examined blending and stratifying methacrylated hyaluronic acid (HAMA) and methacry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a2a0d1a5fdba88ec0aace56b9f2ff0
https://pubmed.ncbi.nlm.nih.gov/35532378
https://pubmed.ncbi.nlm.nih.gov/35532378
Autor:
Silvio Bürge, Markus Neumann, Robert Koban, Franziska Schwarz, Tobias Lam, Lutz Kloke, Heinz Ellerbrok
Publikováno v:
Viruses
Viruses, Vol 12, Iss 1298, p 1298 (2020)
Volume 12
Issue 11
Viruses, Vol 12, Iss 1298, p 1298 (2020)
Volume 12
Issue 11
Studies of virus&ndash
host interactions in vitro may be hindered by biological characteristics of conventional monolayer cell cultures that differ from in vivo infection. Three-dimensional (3D) cell cultures show more in vivo-like characteristi
host interactions in vitro may be hindered by biological characteristics of conventional monolayer cell cultures that differ from in vivo infection. Three-dimensional (3D) cell cultures show more in vivo-like characteristi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a102003164f9e26fac1eb5d8ac280c67
https://pubmed.ncbi.nlm.nih.gov/33198291
https://pubmed.ncbi.nlm.nih.gov/33198291