Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Lutz Kloke"'
Autor:
Anna-Klara Amler, Domenic Schlauch, Selin Tüzüner, Alexander Thomas, Norbert Neckel, Ingeborg Tinhofer, Max Heiland, Roland Lauster, Lutz Kloke, Carmen Stromberger, Susanne Nahles
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Radiotherapy of head and neck squamous cell carcinoma can lead to long-term complications like osteoradionecrosis, resulting in severe impairment of the jawbone. Current standard procedures require a 6-month wait after irradiation before den
Externí odkaz:
https://doaj.org/article/4796e467585e46808a71b4d930f1e3f5
Autor:
Rodrigo M. Florentino, Kazutoyo Morita, Nils Haep, Takashi Motomura, Ricardo Diaz-Aragon, Lanuza A.P. Faccioli, Alexandra Collin de l’Hortet, Zeliha Cetin, Carla Frau, Lawrence Vernetti, Anna-Klara Amler, Alexander Thomas, Tobias Lam, Lutz Kloke, Kazuki Takeishi, D. Lansing Taylor, Ira J. Fox, Alejandro Soto-Gutierrez
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105503- (2022)
Summary: Advances in cellular engineering, as well as gene, and cell therapy, may be used to produce human tissues with programmable genetically enhanced functions designed to model and/or treat specific diseases. Fabrication of synthetic human liver
Externí odkaz:
https://doaj.org/article/456852f3c07c4362a0ae4b0b01b19d89
Autor:
Anna-Klara Amler, Alexander Thomas, Selin Tüzüner, Tobias Lam, Michel-Andreas Geiger, Anna-Elisabeth Kreuder, Chris Palmer, Susanne Nahles, Roland Lauster, Lutz Kloke
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Jawbone differs from other bones in many aspects, including its developmental origin and the occurrence of jawbone-specific diseases like MRONJ (medication-related osteonecrosis of the jaw). Although there is a strong need, adequate in vitro
Externí odkaz:
https://doaj.org/article/a55c496c29ff4ecdb9bf2348d395f254
Autor:
Nina Hedemann, Alexander Thomas, Nils Tribian, Lutz Kloke, Dirk Bauerschlag, Marion van Mackelenbergh
Publikováno v:
Cancer Research. 83:P2-15
Although multi-modal and ablative treatment strategies for breast cancer are becoming more popular, partial or full mastectomy is still a most common intervention. While proving to be effective in curing the cancer, it leaves the patient disfigured,
Autor:
Laura Grunewald, Tobias Lam, Lena Andersch, Anika Klaus, Silke Schwiebert, Annika Winkler, Anton Gauert, Anja I. Heeren-Hagemann, Kathy Astrahantseff, Filippos Klironomos, Alexander Thomas, Hedwig E. Deubzer, Anton G. Henssen, Angelika Eggert, Johannes H. Schulte, Kathleen Anders, Lutz Kloke, Annette Künkele
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chimeric antigen receptor (CAR) T cell performance against solid tumors in mouse models and clinical trials is often less effective than predicted by CAR construct selection in two-dimensional (2D) cocultures. Three-dimensional (3D) solid tumor archi
Externí odkaz:
https://doaj.org/article/36d3f87310c541579111c11eb4745bb7
Autor:
Anna-Klara Amler, Patrick H. Dinkelborg, Domenic Schlauch, Jacob Spinnen, Stefan Stich, Roland Lauster, Michael Sittinger, Susanne Nahles, Max Heiland, Lutz Kloke, Carsten Rendenbach, Benedicta Beck-Broichsitter, Tilo Dehne
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 796 (2021)
Reconstruction of segmental bone defects by autologous bone grafting is still the standard of care but presents challenges including anatomical availability and potential donor site morbidity. The process of 3D bioprinting, the application of 3D prin
Externí odkaz:
https://doaj.org/article/5526d70f95bc4b49ab122dcddf9383ab
Autor:
Robert Koban, Tobias Lam, Franziska Schwarz, Lutz Kloke, Silvio Bürge, Heinz Ellerbrok, Markus Neumann
Publikováno v:
Viruses, Vol 12, Iss 11, p 1298 (2020)
Studies of virus–host interactions in vitro may be hindered by biological characteristics of conventional monolayer cell cultures that differ from in vivo infection. Three-dimensional (3D) cell cultures show more in vivo-like characteristics and ma
Externí odkaz:
https://doaj.org/article/9bc11e0a675e445490146990f4a2c434
Autor:
Isabel Orellano, Alexander Thomas, Aaron Herrera, Erik Brauer, Dag Wulsten, Ansgar Petersen, Lutz Kloke, Georg N. Duda
Nutrient supply via a functional vasculature is essential during regenerative processes, tissue growth, and homeostasis. 3D bioprinting offers the opportunity to engineer vascularized constructs by combining cells and biocompatible materials in speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedd32775c057a5adcca29116bebae26
Autor:
Angelika Rose, Caroline von Spee-Mayer, Lutz Kloke, Kaiyin Wu, Anja Kühl, Philipp Enghard, Gerd-Rüdiger Burmester, Gabriela Riemekasten, Jens Y. Humrich
Publikováno v:
Cells, Vol 8, Iss 10, p 1234 (2019)
An acquired deficiency of interleukin-2 (IL-2) and related disturbances in regulatory T cell (Treg) homeostasis play an important role in the pathogenesis of systemic lupus erythematosus (SLE). Low-dose IL-2 therapy was shown to restore Treg homeosta
Externí odkaz:
https://doaj.org/article/6c6ebae72a8047be855d2126190e7c85
Autor:
Lennard K. Shopperly, Jacob Spinnen, Jan‐Philipp Krüger, Michaela Endres, Michael Sittinger, Tobias Lam, Lutz Kloke, Tilo Dehne
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterialsREFERENCES. 110(10)
Stereolithographic bioprinting holds great promise in the quest for creating artificial, biomimetic cartilage-like tissue. To introduce a more biomimetic approach, we examined blending and stratifying methacrylated hyaluronic acid (HAMA) and methacry