Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Lutz Gieselmann"'
Autor:
Christoph Kreer, Cosimo Lupo, Meryem S. Ercanoglu, Lutz Gieselmann, Natanael Spisak, Jan Grossbach, Maike Schlotz, Philipp Schommers, Henning Gruell, Leona Dold, Andreas Beyer, Armita Nourmohammad, Thierry Mora, Aleksandra M. Walczak, Florian Klein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract HIV-1 broadly neutralizing antibodies (bNAbs) are able to suppress viremia and prevent infection. Their induction by vaccination is therefore a major goal. However, in contrast to antibodies that neutralize other pathogens, HIV-1-specific bN
Externí odkaz:
https://doaj.org/article/e900725c8c9741e5a635d16c5aac862f
Autor:
Jingwei Zhang, Thomas Sommermann, Xun Li, Lutz Gieselmann, Kathrin de la Rosa, Maria Stecklum, Florian Klein, Christine Kocks, Klaus Rajewsky
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionEpstein-Barr virus (EBV) infection in humans is associated with a wide range of diseases including malignancies of different origins, most prominently B cells. Several EBV latent genes are thought to act together in B cell immortalization
Externí odkaz:
https://doaj.org/article/8852a3cd953b41d59483648d9256e588
Autor:
Robert Biesen, Florian Kurth, Jan Zernicke, Florian Klein, Jens Klotsche, Amanthi Nadira Arumahandi de Silva, Leonie Maria Frommert, Alexander ten Hagen, Elisa Habermann, Lutz Gieselmann, Pinkus Tober-Lau, Fredrik Nils Albach, Elvin Ahmadov, Leif Erik Sander
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objective The level of neutralising capacity against Omicron BA.1 and BA.2 after third COVID-19 vaccination in patients on paused or continuous methotrexate (MTX) therapy is unclear.Methods In this observational cohort study, neutralising serum activ
Externí odkaz:
https://doaj.org/article/84ca7dad6d3b427d82aed33a4720b1b0
Autor:
Meryem Seda Ercanoglu, Lutz Gieselmann, Sabrina Dähling, Nareshkumar Poopalasingam, Susanne Detmer, Manuel Koch, Michael Korenkov, Sandro Halwe, Michael Klüver, Veronica Di Cristanziano, Hanna Janicki, Maike Schlotz, Johanna Worczinski, Birgit Gathof, Henning Gruell, Matthias Zehner, Stephan Becker, Kanika Vanshylla, Christoph Kreer, Florian Klein
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103951- (2022)
Summary: Preexisting immunity against SARS-CoV-2 may have critical implications for our understanding of COVID-19 susceptibility and severity. The presence and clinical relevance of a preexisting B cell immunity remain to be fully elucidated. Here, w
Externí odkaz:
https://doaj.org/article/2404de6fd5954a088328929e1de3cfe8
Autor:
Max Augustin, MD, Philipp Schommers, M.D. PhD., Melanie Stecher, Ph.D., Felix Dewald, M.D., Lutz Gieselmann, M.D., Henning Gruell, M.D., Carola Horn, M.D., Kanika Vanshylla, Ph.D., Veronica Di Cristanziano, M.D., Luise Osebold, Maria Roventa, Toqeer Riaz, Nikolai Tschernoster, M.Sc, Janine Altmueller, M.D., Leonard Rose, M.D., Susanne Salomon, Ph.D., Vanessa Priesner, M.D., Jan Christoffer Luers, Prof., Christian Albus, Prof., Stephan Rosenkranz, Prof., Birgit Gathof, Prof., Gerd Fätkenheuer, Prof., Michael Hallek, Prof., Florian Klein, Prof., Isabelle Suárez, M.D., Clara Lehmann, Prof.
Publikováno v:
The Lancet Regional Health. Europe, Vol 6, Iss , Pp 100122- (2021)
Background: While the leading symptoms during coronavirus disease 2019 (COVID-19) are acute and the majority of patients fully recover, a significant fraction of patients now increasingly experience long-term health consequences. However, most data a
Externí odkaz:
https://doaj.org/article/e5d644b7a4e54dd5a3dde9608aaa3500
Autor:
Sebastian J Theobald, Christoph Kreer, Sahamoddin Khailaie, Agnes Bonifacius, Britta Eiz-Vesper, Constanca Figueiredo, Michael Mach, Marija Backovic, Matthias Ballmaier, Johannes Koenig, Henning Olbrich, Andreas Schneider, Valery Volk, Simon Danisch, Lutz Gieselmann, Meryem Seda Ercanoglu, Martin Messerle, Constantin von Kaisenberg, Torsten Witte, Frank Klawonn, Michael Meyer-Hermann, Florian Klein, Renata Stripecke
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008560 (2020)
Human cytomegalovirus (HCMV) causes serious complications to immune compromised hosts. Dendritic cells (iDCgB) expressing granulocyte-macrophage colony-stimulating factor, interferon-alpha and HCMV-gB were developed to promote de novo antiviral adapt
Externí odkaz:
https://doaj.org/article/c1d9d22801744c638a64acbe75f4086c
Autor:
Janine J Wilden, Andre van Krüchten, Lutz Gieselmann, Eike R Hrincius, Stefanie Deinhardt-Emmer, Karoline F Haupt, Hannah F Preugschas, Silke Niemann, Stephan Ludwig, Christina Ehrhardt
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233052 (2020)
Severe influenza virus (IV) infections still represent a major challenge to public health. To combat IV infections, vaccines and antiviral compounds are available. However, vaccine efficacies vary with very limited to no protection against newly emer
Externí odkaz:
https://doaj.org/article/b83aef6bb65b438cafc89f0cf83e29c2
Autor:
Kirsten Alexandra Eberhardt, Felix Dewald, Eva Heger, Lutz Gieselmann, Kanika Vanshylla, Maike Wirtz, Franziska Kleipass, Wibke Johannis, Philipp Schommers, Henning Gruell, Karl August Brensing, Roman-Ulrich Müller, Max Augustin, Clara Lehmann, Manuel Koch, Florian Klein, Veronica Di Cristanziano
Publikováno v:
Microorganisms, Vol 9, Iss 4, p 733 (2021)
Background: The investigation of the antibody response to SARS-CoV-2 represents a key aspect in facing the COVID-19 pandemic. In the present study, we compared the new Immundiagnostik IDK® anti-SARS-CoV-2 S1 IgG assay with four widely-used commercia
Externí odkaz:
https://doaj.org/article/6c630c7a08bd4ce88b38dcb9bbf93f92
Autor:
Caelan E. Radford, Philipp Schommers, Lutz Gieselmann, Katharine H. D. Crawford, Bernadeta Dadonaite, Timothy C. Yu, Adam S. Dingens, Julie Overbaugh, Florian Klein, Jesse D. Bloom
Publikováno v:
bioRxiv
Understanding the specificities of human serum antibodies that broadly neutralize HIV can inform prevention and treatment strategies. Here we describe a deep mutational scanning system that can measure the effects of combinations of mutations to HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0478771c3ce8ea4658bb2834d04090
https://europepmc.org/articles/PMC10055425/
https://europepmc.org/articles/PMC10055425/
Autor:
Christoph Kreer, Cosimo Lupo, Meryem S. Ercanoglu, Lutz Gieselmann, Natanael Spisak, Jan Grossbach, Maike Schlotz, Philipp Schommers, Henning Gruell, Leona Dold, Andreas Beyer, Armita Nourmohammad, Thierry Mora, Aleksandra M. Walczak, Florian Klein
HIV-1 broadly neutralizing antibodies (bNAbs) are able to suppress viremia and prevent infection. Their induction by vaccination is therefore a major goal. However, in contrast to antibodies that neutralize other pathogens, HIV-1-specific bNAbs frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0deefd9e2906fa19b52d9dc926238edf
https://doi.org/10.1101/2022.07.11.499584
https://doi.org/10.1101/2022.07.11.499584