Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lutz G.W. Hilgenberg"'
Publikováno v:
Molecular and Cellular Neuroscience. 37:770-780
Integrins regulate cytoplasmic calcium levels ([Ca(2+)]i) in various cell types but information on activities in neurons is limited. The issue is of current interest because of the evidence that both integrins and changes in [Ca(2+)]i are required fo
Autor:
Xicui Sun, F-S Hou, Martin A. Smith, H-W Oh, Elly M. Hol, Lutz G.W. Hilgenberg, Steven S. Schreiber, Zhiqun Tan, Diane K. O'Dowd, F.W. van Leeuwen
Publikováno v:
Cell Death & Differentiation. 14:1721-1732
A dinucleotide deletion in human ubiquitin (Ub) B messenger RNA leads to formation of polyubiquitin (UbB) + 1, which has been implicated in neuronal cell death in Alzheimer’s and other neurodegenerative diseases. Previous studies demonstrate that U
Autor:
Johanna Kölln, Neal Hermanowicz, Reng-Rong Da, Michael J. Olek, Yufen Qin, Yiping Zhang, Stanley van den Noort, Edzard Spillner, Lutz G.W. Hilgenberg, Hui-Min Ren, Martin A. Smith
Publikováno v:
The Journal of Immunology. 177:5652-5658
Our previous results revealed that Igs in lesions and single chain variable fragment Abs (scFv-Abs) generated from clonal B cells in the cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) bind to axons in MS brains. To study the axo
Autor:
Rashed M. Nagra, Stanley van den Noort, Wen-Zhong Guo, Reng-Rong Da, Yiping Zhang, Martin A. Smith, Sudhir Gupta, Raymond A. Sobel, Hui-Min Ren, Yufen Qin, Lutz G.W. Hilgenberg, Michael J. Olek, Wallace W. Tourtellotte, Richard T. Robertson
Publikováno v:
Journal of Clinical Immunology. 25:254-264
Demyelination and axonal loss have been described as the histological hallmarks of inflammatory lesions of multiple sclerosis (MS) and are the pathological correlates of persistent disability. However, the immune mechanisms underlying axonal damage i
Autor:
Martin A. Smith, Lutz G.W. Hilgenberg
Publikováno v:
Journal of Neurobiology. 61:289-300
Agrin has been implicated in multiple aspects of central nervous system (CNS) neuron differentiation and function including neurite formation, synaptogenesis, and synaptic transmission. However, little is known about the signaling mechanisms whereby
Autor:
Lutz G.W. Hilgenberg, Martin A. Smith
Publikováno v:
Neuroreport. 13:1485-1495
The extracellular matrix molecule agrin mediates the motor neuron induced accumulation of acetylcholine receptors (AChR) at the neuromuscular junction. Agrin is also present in the CNS. However, while its spatiotemporal pattern of expression is consi
Autor:
Lutz G.W. Hilgenberg, Kathryn Miles
Publikováno v:
Journal of Cell Science. 108:51-61
Protein kinase C (PKC) is a family of protein serine/threonine kinases consisting of multiple isoforms whose distinct physiological roles within cells are unknown. The message encoding the nPKC theta isoform, a member of the novel calcium-independent
Autor:
Thomas Kemmerly, Lutz G.W. Hilgenberg, Bryan Pham, Diane K. O'Dowd, Maria Ortega, Martin A. Smith, Saif Walid
Publikováno v:
The Journal of biological chemistry. 284(25)
Drugs that inhibit Na,K-ATPases, such as digoxin and ouabain, alter cardiac myocyte contractility. We recently demonstrated that agrin, a protein first identified at the vertebrate neuromuscular junction, binds to and regulates the activity of alpha3
Autor:
Tahseen Mozaffar, Erika Strandberg, Martin A. Smith, Kazuko Abe, Lutz G.W. Hilgenberg, Ranjan Gupta
Chronic nerve compression injuries (CNC) are progressive demyelinating disorders characterized by a gradual decline of the nerve conduction velocity (NCV) in the affected nerve region. CNC injury induces a robust Schwann cell response with axonal spr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3056014f1c2680e37bc435694ad5472
https://europepmc.org/articles/PMC2670070/
https://europepmc.org/articles/PMC2670070/
Autor:
A. Janetzko, Hille Tekotte, A. Flaccus, P Gao, Lutz G.W. Hilgenberg, Renée K. Margolis, Richard U. Margolis, Uwe Rauch
Publikováno v:
Journal of Biological Chemistry. 266:14785-14801
A panel of monoclonal antibodies prepared to the chondroitin sulfate proteoglycans of rat brain was used for their immunocytochemical localization and isolation of individual proteoglycan species by immunoaffinity chromatography. One of these proteog