Zobrazeno 1 - 10
of 435
pro vyhledávání: '"Lutz, Frölich"'
Autor:
Annette Löffler, Florian Beier, Robin Bekrater-Bodmann, Lucrezia Hausner, Simon Desch, Stefano Silvoni, Dieter Kleinböhl, Martin Löffler, Frauke Nees, Lutz Frölich, Herta Flor
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104896- (2024)
Summary: Background: Sensory impairment has been related to age-associated cognitive decline. While these associations were investigated primarily in the auditory and visual domain, other senses such as touch have rarely been studied. Thus, it remain
Externí odkaz:
https://doaj.org/article/38fb1b5c846d483bae63ddfe36923a4f
Autor:
Prof. Dr. med. Dipl.-Phys. Matthias Riepe, Prof. Dr. med. Lutz Frölich, Dr. theol. h.c. Jürgen Gohde, Dr. med. Harald Herholz MPH, Prof. Dr. med. Frank Jessen, Prof. Dr. rer.pol. h.c. Herbert Rebscher, Dr. med. Jürgen Bausch
Publikováno v:
Monitor Versorgungsforschung, Vol 2023, Iss 03, Pp 55-61 (2023)
Um die öffentliche Diskussion zu grundlegenden Themen hinsichtlich Diagnostik, Therapie und Versorgung von Demenz-patient:innen zu etablieren, die konkreten Handlungsbedarf aufzeigen, hat sich zu Beginn des Jahres 2020 das „Interdisziplinäre Di
Externí odkaz:
https://doaj.org/article/9b1e14e9c4744bf7b0c3dd5d53964216
Autor:
Linus Jönsson, Anders Wimo, Ron Handels, Gunilla Johansson, Mercè Boada, Sebastiaan Engelborghs, Lutz Frölich, Frank Jessen, Patrick Gavin Kehoe, Milica Kramberger, Alexandre de Mendonςa, Pierre Jean Ousset, Nikolaos Scarmeas, Pieter Jelle Visser, Gunhild Waldemar, Bengt Winblad
Publikováno v:
The Lancet Regional Health. Europe, Vol 29, Iss , Pp 100657- (2023)
Summary: Lecanemab, an anti-amyloid antibody with effects on biomarker and clinical endpoints in early Alzheimer's Disease (AD), was granted accelerated approval by the FDA in 2023 and regulatory review in Europe is ongoing. We estimate the populatio
Externí odkaz:
https://doaj.org/article/e114750f7aa643c0a957c3082f18abf0
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Frailty has been associated with a decline in sensory and motor function. However, given that different frailty measures were shown to overlap but also differ in their diagnostic properties, sensory and motor correlates of frailty
Externí odkaz:
https://doaj.org/article/d4213a58c79c4c1aa39e4750586d122b
Autor:
Bruno Mario Cesana, Eleni Poptsi, Magda Tsolaki, Sverre Bergh, Alfonso Ciccone, Emmanuel Cognat, Andrea Fabbo, Sara Fascendini, Giovanni B. Frisoni, Lutz Frölich, Maria Cristina Jori, Patrizia Mecocci, Paola Merlo, Oliver Peters, Carlo Alberto Defanti
Publikováno v:
Brain Sciences, Vol 13, Iss 7, p 1025 (2023)
Background: One of the most widely used instruments for assessing agitation in dementia patients is the Cohen-Mansfield Agitation Inventory (CMAI), nevertheless no global score has been proposed. The aim of this study is: (a) to conduct a confirmator
Externí odkaz:
https://doaj.org/article/a0e5dcb2365e429ca3a14bde298067ad
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Frailty is characterized by an age-related decline in multiple physiological systems, leading to a high vulnerability to stressors, adverse health outcomes, and low quality of life. Neuroscientific models of pathological aging emp
Externí odkaz:
https://doaj.org/article/e9de755bd3ef4fcb9f64d2a0ca16859e
Autor:
Shahzad Ahmad, Adelina Orellana, Isabelle Kohler, Lutz Frölich, Itziar de Rojas, Silvia Gil, Mercè Boada, Isabel Hernández, Lucrezia Hausner, Margot H. M. Bakker, Alfredo Cabrera-Socorro, Najaf Amin, Alfredo Ramírez, Agustín Ruiz, Thomas Hankemeier, Cornelia M. Van Duijn
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2020)
Abstract Background Lysophosphatidic acids (LPAs) are bioactive signaling phospholipids that have been implicated in Alzheimer’s disease (AD). It is largely unknown whether LPAs are associated with AD pathology and progression from mild cognitive i
Externí odkaz:
https://doaj.org/article/ac7c9027ac5f4c9bbafbd9c37495b270
Autor:
Elles Konijnenberg, Betty M. Tijms, Johan Gobom, Valerija Dobricic, Isabelle Bos, Stephanie Vos, Magda Tsolaki, Frans Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, Lutz Frölich, Simon Lovestone, Johannes Streffer, Lars Bertram, Kaj Blennow, Charlotte E. Teunissen, Robert Veerhuis, August B. Smit, Philip Scheltens, Henrik Zetterberg, Pieter Jelle Visser
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Aggregation of amyloid β into plaques in the brain is one of the earliest pathological events in Alzheimer’s disease (AD). The exact pathophysiology leading to dementia is still uncertain, but the apolipoprotein E (APOE) ε4 ge
Externí odkaz:
https://doaj.org/article/a2719f0f9fab41c2bb1efa1068070aa7
Autor:
Anna-Sophia Wahl, Martin Löffler, Lucrezia Hausner, Michaela Ruttorf, Frauke Nees, Lutz Frölich
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Intracranial arachnoid cysts are usually benign congenital findings of neuroimaging modalities, sometimes however, leading to focal neurological and psychiatric comorbidities. Whether primarily clinically silent cysts may become c
Externí odkaz:
https://doaj.org/article/d58707ed5a6f4a33abc898415459a5bc
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2019)
Abstract Background There are currently no approved treatments for the prodromal stage of Alzheimer’s disease (AD). Approved symptomatic treatments for mild-to-moderate AD include acetylcholinesterase inhibitors and memantine, but more efficacious
Externí odkaz:
https://doaj.org/article/360e24efd56d43f9b8a6907e0297c698