Lack of efflux of diglycolic acid from proximal tubule cells leads to its accumulation and to toxicity of diethylene glycol.

Autor: Tobin JD; Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71130, USA., Robinson CN; Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71130, USA., Luttrell-Williams ES; Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71130, USA., Landry GM; Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71130, USA., McMartin KE; Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71130, USA. Electronic address: kenneth.mcmartin@lsuhs.edu.

Publikováno v: Toxicology letters [Toxicol Lett] 2023 Apr 15; Vol. 379, pp. 48-55. Date of Electronic Publication: 2023 Mar 22.

Hydroxychloroquine is associated with lower platelet activity and improved vascular health in systemic lupus erythematosus.

Autor: Cornwell MG; Institute for Systems Genetics, NYU Langone Health, New York City, New York, USA.; Division of Translational Medicine, New York University School of Medicine, New York City, New York, USA., Luttrell-Williams ES; Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York City, New York, USA., Golpanian M; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York City, New York, USA., El Bannoudi H; Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York City, New York, USA., Myndzar K; Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York City, New York, USA., Izmirly P; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York City, New York, USA., Belmont HM; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York City, New York, USA., Katz S; Division of Translational Medicine, New York University School of Medicine, New York City, New York, USA., Smilowitz NR; Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York City, New York, USA., Engel A; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York City, New York, USA., Clancy R; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York City, New York, USA., Ruggles K; Institute for Systems Genetics, NYU Langone Health, New York City, New York, USA.; Division of Translational Medicine, New York University School of Medicine, New York City, New York, USA., Buyon JP; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York City, New York, USA., Berger JS; Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine, New York City, New York, USA Jeffrey.Berger@nyumc.org.

Publikováno v: Lupus science & medicine [Lupus Sci Med] 2021 Mar; Vol. 8 (1).