Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lutfiya Miller-Pinsler"'
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 30-38 (2016)
The breast cancer 1 (brca1) gene is associated with breast and ovarian cancers, and heterozygous (+/−) brca1 knockout progeny develop normally, suggesting a negligible developmental impact. However, our results show BRCA1 plays a broader biological
Externí odkaz:
https://doaj.org/article/e2371794ce1c4f46939854edb66cbde3
Autor:
Johnathan Furr, B Collins, Keith R. Shockley, Helen Cunny, Charles D. Hébert, AtLee T. D. Watson, Lori Smith, Lutfiya Miller-Pinsler, Kristin Aillon, Vicki Sutherland, Guanhua Xie, Trey Vinke, Suramya Waidyanatha, Barry S. McIntyre
Publikováno v:
Toxicol Sci
Human exposure to boron occurs primarily through diet and drinking water sources. Animal studies have found that reduced fetal weight following gestational exposure to boron (as boric acid) is the most sensitive toxicological effect. However, recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15eb29ab3dec1006a18db17f44373153
https://europepmc.org/articles/PMC7357175/
https://europepmc.org/articles/PMC7357175/
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 108:108-130
In utero exposure of mouse progeny to alcohol (ethanol, EtOH) and methamphetamine (METH) causes substantial postnatal neurodevelopmental deficits. One emerging pathogenic mechanism underlying these deficits involves fetal brain production of reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9a5c0814f2c40367d692cae8e1d355
https://doi.org/10.1002/bdrc.21134
https://doi.org/10.1002/bdrc.21134
Autor:
Natasha R. Catlin, Eve Mylchreest, Lutfiya Miller-Pinsler, Vicki Sutherland, Helen Cunny, Paul M. D. Foster, Suramya Waidyanatha, Barry S. McIntyre
Publikováno v:
Birth defects research. 110(18)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88de0b5ed63fc71aa3a75da7e37ff0cd
https://pubmed.ncbi.nlm.nih.gov/30362293
https://pubmed.ncbi.nlm.nih.gov/30362293
Autor:
Paul M. D. Foster, Barry S. McIntyre, Eve Mylchreest, Helen Cunny, Lutfiya Miller-Pinsler, Suramya Waidyanatha, Natasha R. Catlin, Vicki Sutherland
Dietary supplement and natural product use is increasing within the United States, resulting in growing concern for exposure in vulnerable populations, including young adults and women of child-bearing potential. Vinpocetine is a semi-synthetic deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57e129cb8026b520ba1f51f89e0793c
https://europepmc.org/articles/PMC5980693/
https://europepmc.org/articles/PMC5980693/
Autor:
Peter G. Wells, Lutfiya Miller-Pinsler
Publikováno v:
Toxicology and Applied Pharmacology. 287:232-239
Reactive oxygen species (ROS) have been implicated in the mechanism of ethanol (EtOH) teratogenicity, but the protective role of the embryonic antioxidative enzyme catalase is unclear, as embryonic activity is only about 5% of maternal levels. We add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191499d4f51c854c28609e2e60db892c
https://doi.org/10.1016/j.taap.2015.06.007
https://doi.org/10.1016/j.taap.2015.06.007
Publikováno v:
Archives of Toxicology. 90:717-730
Methanol (MeOH) teratogenicity in rodents may be mediated in part by reactive oxygen species (ROS), the source of which is unknown. To determine if MeOH enhances embryonic ROS-producing NADPH oxidases (NOXs), p22phox mRNA and protein and oxidatively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8ff595fa5630d0e6829e1dfe3fed81
https://doi.org/10.1007/s00204-015-1482-0
https://doi.org/10.1007/s00204-015-1482-0
Publikováno v:
Free Radical Biology and Medicine. 78:23-29
Studies in mice with deficient antioxidative enzymes have shown that physiological levels of reactive oxygen species (ROS) can adversely affect the developing embryo and fetus. Herein, DNA repair-deficient progeny of oxoguanine glycosylase 1 (ogg1)-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b417a059c384c600884157a6fa9d6e
https://doi.org/10.1016/j.freeradbiomed.2014.09.026
https://doi.org/10.1016/j.freeradbiomed.2014.09.026
Autor:
Lutfiya Miller-Pinsler, Peter G. Wells
Publikováno v:
Archives of Toxicology. 90:415-425
Reactive oxygen species (ROS) have been implicated in the teratogenicity of alcohol (ethanol, EtOH). To determine the involvement of embryonic oxidative DNA damage, DNA repair-deficient oxoguanine glycosylase 1 (ogg1) knockout embryos were exposed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3912765de2eba04f9d2cf351521eec
https://doi.org/10.1007/s00204-014-1397-1
https://doi.org/10.1007/s00204-014-1397-1
Publikováno v:
Oxidative Stress in Applied Basic Research and Clinical Practice ISBN: 9781493914043
The developing embryo and fetus, collectively termed the conceptus, are highly susceptible to the adverse effects of oxidative stress initiated by endogenous processes and by xenobiotics that enhance the formation of reactive oxygen species (ROS). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d557403b0c18e3de304ba18a0c15125b
https://doi.org/10.1007/978-1-4939-1405-0_1
https://doi.org/10.1007/978-1-4939-1405-0_1