Major Genetic Drivers of Statin Treatment Response in African Populations and Pharmacogenetics of Dyslipidemia Through a One Health Lens.

Autor: Lusiki, Zizo, Blom, Dirk, Soko, Nyarai D., Malema, Smangele, Jones, Erika, Rayner, Brian, Blackburn, Jonathan, Sinxadi, Phumla, Dandara, Michelle T., Dandara, Collet

Publikováno v: OMICS: A Journal of Integrative Biology; Jun2024, Vol. 28 Issue 6, p261-279, 19p

Major Genetic Drivers of Statin Treatment Response in African Populations and Pharmacogenetics of Dyslipidemia Through a One Health Lens.

Autor: Lusiki Z; Division of Human Genetics, Department of Pathology, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa., Blom D; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa.; Division of Lipidology and Cape Heart Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa., Soko ND; Division of Human Genetics, Department of Pathology, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa., Malema S; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa., Jones E; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa.; Division of Nephrology and Hypertension, Department of Medicine, University of Cape Town, Cape Town, South Africa., Rayner B; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa.; Division of Nephrology and Hypertension, Department of Medicine, University of Cape Town, Cape Town, South Africa., Blackburn J; Division of Chemical and Systems Biology, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa., Sinxadi P; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa.; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa., Dandara MT; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa., Dandara C; Division of Human Genetics, Department of Pathology, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Platform for Pharmacogenomics Research and Translation (PREMED) Unit, South African Medical Research Council (SAMRC), Cape Town, South Africa.

Publikováno v: Omics : a journal of integrative biology [OMICS] 2024 Jun; Vol. 28 (6), pp. 261-279. Date of Electronic Publication: 2023 Nov 14.