Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma.

Autor: Lietz CE; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Newman ET; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Kelly AD; Foundation Medicine, Cambridge, MA, USA., Xiang DH; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Zhang Z; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Luscko CA; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Lozano-Calderon SA; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Ebb DH; Division of Pediatric Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Raskin KA; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Cote GM; Division of Hematology/Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Choy E; Division of Hematology/Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Nielsen GP; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Haibe-Kains B; Department of Medical Biophysics, Princess Margaret Cancer Centre, University of Toronto, Toronto, M5G 2M9, ON, Canada., Aryee MJ; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Spentzos D; Department of Orthopaedic Surgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA. dspentzos@mgh.harvard.edu.

Publikováno v: Communications biology [Commun Biol] 2022 Mar 08; Vol. 5 (1), pp. 213. Date of Electronic Publication: 2022 Mar 08.