Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Lurong Lian"'
Autor:
Marina Martinez, Soyeon Kim, Naomi St. Jean, Shaun O’Brien, Lurong Lian, Jing Sun, Raluca I. Verona, Edmund Moon
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
PD1 blockade to reinvigorate T cells has become part of standard of care for patients with NSCLC across disease stages. However, the majority of patients still do not respond. One potential mechanism of resistance is increased expression of other che
Externí odkaz:
https://doaj.org/article/95b6c66eb3604c28a884fc912e1dd5af
Autor:
Liang Zhao, Chelsea L. Thorsheim, Aae Suzuki, Timothy J. Stalker, Sang H. Min, Lurong Lian, Gregory D. Fairn, Shamshad Cockcroft, Amy Durham, Sriram Krishnaswamy, Charles S. Abrams
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Platelets support tumor metastasis formation. Here, the authors show that the phosphoinositide signaling modulated by PITPα is essential for platelet-mediated tumor metastasis signaling, but surprisingly it is dispensable in hemostasis in mice.
Externí odkaz:
https://doaj.org/article/036c8227c25d4741b3094639be983c32
Autor:
Blanca E Himes, Kseniya Obraztsova, Lurong Lian, Maya Shumyatcher, Ryan Rue, Elena N Atochina-Vasserman, Stella K Hur, Marisa S Bartolomei, Jilly F Evans, Vera P Krymskaya
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197105 (2018)
Lymphangioleiomyomatosis (LAM) is a rare, almost exclusively female lung disease linked to inactivating mutations in tuberous sclerosis complex 2 (TSC2), a tumor suppressor gene that controls cell metabolic state and growth via regulation of the mech
Externí odkaz:
https://doaj.org/article/dc3af48d07f2469fa4b013c8f3428a2a
Autor:
Lurong Lian, Aae Suzuki, Vincent Hayes, Sougata Saha, Xuemei Han, Tao Xu, John R Yates, Mortimer Poncz, Anna Kashina, Charles S. Abrams
Publikováno v:
Haematologica, Vol 99, Iss 3 (2014)
Protein arginylation by arginyl–transfer RNA protein transferase (ATE1) is emerging as a regulator protein function that is reminiscent of phosphorylation. For example, arginylation of β-actin has been found to regulate lamellipodial formation at
Externí odkaz:
https://doaj.org/article/5e0ddbc1dd0e45599d374db3b42b7d9d
Autor:
Aae Suzuki, Jae-Won Shin, Yuhuan Wang, Sang H Min, Morty Poncz, John K Choi, Dennis E Discher, Chris L Carpenter, Lurong Lian, Liang Zhao, Yangfeng Wang, Charles S Abrams
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69315 (2013)
RhoA plays a multifaceted role in platelet biology. During platelet development, RhoA has been proposed to regulate endomitosis, proplatelet formation, and platelet release, in addition to having a role in platelet activation. These processes were pr
Externí odkaz:
https://doaj.org/article/a4b4b9ddf9e04631b1c81f7f3a07ad50
Autor:
Lurong Lian, Inkyung Kang, Ning Zuo, Ryan Rue, Melody A. Swartz, Elena N. Atochina-Vasserman, Vera P. Krymskaya, Thomas N. Wight, Andrew J. Gow, Katharina Maisel, Alexander N. Vasserman, Mervyn J. Merrilees, Evgeniy Eruslanov, Luis Angel, Kseniya Obraztsova
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 59:723-732
Pulmonary lymphangioleiomyomatosis (LAM) is a slow-progressing metastatic disease that is driven by mutations in the tumor suppressor tuberous sclerosis complex 1/2 (TSC1/2). Rapamycin inhibits LAM cell proliferation and is the only approved treatmen
Autor:
Soyeon Kim, Lurong Lian, Naomi St. Jean, Edmund K. Moon, Jing Sun, Raluca Verona, Shaun O'Brien, Marina Martinez
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
PD1 blockade to reinvigorate T cells has become part of standard of care for patients with NSCLC across disease stages. However, the majority of patients still do not respond. One potential mechanism of resistance is increased expression of other che
Autor:
Lurong Lian, Sang H. Min, Liang Zhao, Timothy J. Stalker, Amy C. Durham, Sriram Krishnaswamy, Shamshad Cockcroft, Aae Suzuki, Chelsea Thorsheim, Gregory D. Fairn, Charles S. Abrams
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Platelets are increasingly recognized for their contributions to tumor metastasis. Here, we show that the phosphoinositide signaling modulated by phosphatidylinositol transfer protein type α (PITPα), a protein which shuttles phosphatidylinositol be
Autor:
Martinez, Marina, Soyeon Kim, St. Jean, Naomi, O'Brien, Shaun, Lurong Lian, Sun, Jing, Verona, Raluca I., Moon, Edmund
Publikováno v:
OncoImmunology; 2021, Vol. 10 Issue 1, p1-15, 15p
Autor:
Mortimer Poncz, Tao Xu, John R. Yates, Xuemei Han, Vincent Hayes, Lurong Lian, Anna Kashina, Aae Suzuki, Charles S. Abrams, Sougata Saha
Publikováno v:
Haematologica. 99:554-560
Protein arginylation by arginyl–transfer RNA protein transferase (ATE1) is emerging as a regulator protein function that is reminiscent of phosphorylation. For example, arginylation of β-actin has been found to regulate lamellipodial formation at