Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Luqing Shang"'
Autor:
Jiyan Wang, Hongkai Chang, Meng Su, Huifang Zhao, Yaya Qiao, Yu Wang, Luqing Shang, Changliang Shan, Shuai Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Network pharmacology, as a novel way using bioinformatics to explore drug targets and interactions in cancer, broadens our understanding of drug action, thereby facilitating drug discovery. Here, we utilized network pharmacology to explore the role a
Externí odkaz:
https://doaj.org/article/6973c13e9902441d93d5a9ed0f0ce6de
Autor:
Binghong Xu, Meijun Liu, Sen Ma, Yuying Ma, Si Liu, Luqing Shang, Cheng Zhu, Sheng Ye, Yaxin Wang
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT The fatal pathogen enterovirus 71 (EV71) is a major cause of hand-foot-and-mouth disease (HFMD), which leads to serious neurological syndromes. While there are no effective clinical agents available for EV71 treatment thus far, EV71 3C prote
Externí odkaz:
https://doaj.org/article/54e02fbd16f64b2ba1bf170e6e43a2b5
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2392 (2022)
As the etiological agent for the coronavirus disease 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) challenges the ongoing efforts of vaccine development and drug design. Due to the accumulating cases of breakthrough infections, t
Externí odkaz:
https://doaj.org/article/afa338edfdc346859747e79313210aa8
Autor:
Guo-Qiang Zhang, Hao Chang, Zhiyuan Gao, Yang-ping Deng, Sheng Zeng, Luqing Shang, Dan Ding, Qian Liu
Publikováno v:
ACS Materials Letters. 5:722-729
Autor:
Hao Wang, Rongjuan Pei, Xin Li, Weilong Deng, Shuai Xing, Yanan Zhang, Chen Zhang, Shuai He, Hao Sun, Shuqi Xiao, Jin Xiong, Yecheng Zhang, Xinwen Chen, Yaxin Wang, Yu Guo, Bo Zhang, Luqing Shang
Publikováno v:
European journal of medicinal chemistry. 238
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), as the pathogen of coronavirus disease 2019 (COVID-19), has infected millions of people and took hundreds of thousands of lives. Unfortunately, there is deficiency of effective medicines t
Autor:
Lu Zhang, Xiao Liang, Hao Chang, Qianqian Wang, Jiejie Yang, Dan Qiao, Luqing Shang, Landie Li, Wei Zhao, Ning Liu, Tangliang Shen
Publikováno v:
ACS Sensors. 5:2247-2254
A customizable fluorescent probe platform that can be used to detect various bioactive analytes offers significant potential for engineering a wide range of bioprobes with diverse sensing and imaging functions. Here, we show a facile and innovative s
Autor:
Yu Guo, Hao Wang, Weilong Deng, Zheng Yin, Ying Zhang, Jixue Sun, Dongmei Li, Shuai He, Guobang Li, Wei Zhao, Luqing Shang
Publikováno v:
ACS Catalysis
Coronavirus 3C-like protease (3CLPro) is a highly conserved cysteine protease employing a catalytic dyad for its functions. 3CLPro is essential to the viral life cycle and, therefore, is an attractive target for developing antiviral agents. However,
Autor:
Meng Meng, Rimo Xi, Dan Ding, Shuo Wang, Luqing Shang, Yanqi Qiao, Xiujie Zhao, Jie Yang, Heqi Gao, Wei Zhao, Zhiwen Fan, Chen Yun, Yongmei Yin, Wenting Liu, Xinmin Yue, Tangliang Shen, Xuelin Zhan
Publikováno v:
ACS Applied Materials & Interfaces. 12:16114-16124
Near-infrared (NIR) fluorescent probes can deeply penetrate through tissues with little damage. To facilitate image-guided theranostics, researchers usually apply a desired amount of photosensitizers to achieve effective photothermal responses. Howev
Autor:
Rui Luo, Zihe Rao, Ming Wu, Junxiu Nong, Zhiyong Lou, Jie Qing, Bi-Sen Ding, Luqing Shang, Xinwen Chen, Debin Zeng, Jizheng Chen, Lei Liu, Lin Cao, Qinkai Wu
Publikováno v:
ACS Chemical Biology. 15:1232-1241
Upon sensing pathogen-associated patterns and secreting interferons (IFNs) into the environment, host cells perceive extracellular type I IFNs by the IFNα/β receptors IFNAR1 and IFNAR2 to stimulate downstream innate immune signaling cascades. Throu
Autor:
Luqing Shang, Si Liu, Sen Ma, Yuying Ma, Sheng Ye, Binghong Xu, Meijun Liu, Yaxin Wang, Cheng Zhu
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
Microbiology Spectrum
Microbiology Spectrum
The fatal pathogen enterovirus 71 (EV71) is a major cause of hand-foot-and-mouth disease (HFMD), which leads to serious neurological syndromes. While there are no effective clinical agents available for EV71 treatment thus far, EV71 3C protease (3Cpr