Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Luqin Si"'
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1764 (2024)
Given the critical role of dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) mouse models in the appraisal of associated therapeutic drugs, the optimization of the administration method and dosages is of paramount importance. Therefore, UC
Externí odkaz:
https://doaj.org/article/5008a468b2734749896d27b44a54032b
Autor:
Li Kang, Dan Li, Xin Jiang, Yao Zhang, Minhong Pan, Yixin Hu, Luqin Si, Yongjun Zhang, Jiangeng Huang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Polygoni Multiflori Radix (PMR), the dried root of Polygonum Multiflorum Thunb., has been widely used as traditional Chinese medicines in clinical practice for centuries. However, the frequently reported hepatotoxic adverse effects hindered its safe
Externí odkaz:
https://doaj.org/article/be5767abe9b847e7af2b3a92da09c7c3
Autor:
Liping Xiang, Jian Xu, Wanyu Liu, Yue Wu, Xin Jiang, Yixin Hu, Yao Zhang, Qiang Yang, Zhe Wang, Yuejun Yang, Sanlan Wu, Luqin Si, Jiangeng Huang, Yongjun Zhang
Publikováno v:
Separations, Vol 9, Iss 12, p 407 (2022)
Tartary buckwheat, a gluten-free pseudocereal, has received considerable attention owing to its unique nutritional ingredients and beneficial health effects such as anti-tumor, anti-oxidation, anti-inflammation and hepatoprotective activities. Pharma
Externí odkaz:
https://doaj.org/article/36ea46cd853d483c96748ee475eb4e1f
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1830 (2022)
The pH–induced crystallization of weakly basic drugs in the small intestine limits oral bioavailability. In this study, we investigated the solubilization and inhibitory effects on nintedanib in the presence of enteric polymers (HPMCAS LG, HPMCAS M
Externí odkaz:
https://doaj.org/article/7b7f7e708a7946d2a0e1df0791a148c2
Autor:
Yuancai Liu, Jun Gan, Wanyu Liu, Xin Zhang, Jian Xu, Yue Wu, Yuejun Yang, Luqin Si, Gao Li, Jiangeng Huang
Publikováno v:
Pharmaceutics, Vol 11, Iss 10, p 525 (2019)
Alcoholic liver disease (ALD) has become a critical global public health issue worldwide. Tartary buckwheat extracts exhibit potential therapeutic effects against ALD due to its antioxidant and anti-inflammatory activities. However, in vivo pharmacok
Externí odkaz:
https://doaj.org/article/9ac8bbe173674708adce6c93253cd34e
Publikováno v:
Pharmaceutics, Vol 11, Iss 1, p 38 (2019)
TJ0711∙HCl, which is a novel α1/β1 adrenoceptor blocking agent with a ratio of 1:1 for α1/β1, is designed to treat and prevent perioperative hypertension. M1 and M3 were identified as important metabolites in vitro for either antihypertension a
Externí odkaz:
https://doaj.org/article/14e224fdcfb34fc08ac2f03d2fa7c026
Autor:
Xin Zhang, Ming Jin, Yuping Liu, Qimingxing Chen, Luqin Si, Gao Li, Yonghui Zhang, Jiangeng Huang
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 87 (2018)
Kinsenoside (KD), an active compound isolated from Anoectochilus roxburghii, has demonstrated multiple pharmacological activities including hepatoprotection, antihyperliposis, antihyperglycemia, and antiosteoporosis. To the best of our knowledge, the
Externí odkaz:
https://doaj.org/article/5b09849ab90e4796b2d1ba5e3785b466
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 14, Iss 2 (2011)
PURPOSE: To determine experimentally the intestinal permeability of the anticancer prodrug irinotecan, and to quantify the amount of its cytotoxic metabolite SN-38 that is intestinally excreted (exsorped) as a predictor of intestinal toxicity, and to
Externí odkaz:
https://doaj.org/article/12893ee58d984c31b6031dbbca72fe7d
Publikováno v:
Drug Delivery and Translational Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::394be30031e3cd68f34688a03a03e4d0
https://doi.org/10.1007/s13346-023-01317-8
https://doi.org/10.1007/s13346-023-01317-8
Autor:
Cheng Qin, Anhua Wei, Jiangeng Huang, Xin Jiang, Luqin Si, Xueyan Yin, Wanyu Liu, Yongjun Zhang, Yaping Li
Publikováno v:
Revista Brasileira de Farmacognosia. 31:772-778
Protoapigenone, a unique class of natural flavonoid, exerted significant cytotoxic and antitumoral activities. A simple, sensitive, and rapid LC–MS/MS method for the quantification of protoapigenone in plasma was developed and validated to obtain t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d845d5ad79fd42dbad7e87c3895f5f79
https://doi.org/10.1007/s43450-021-00205-x
https://doi.org/10.1007/s43450-021-00205-x