Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lupus Erythematosus, Systemic/ genetics/ immunology"'
Autor:
B. L. Kotzin, Michael T. Falta, Trine N. Jørgensen, Johne Kappler, Pilippa Marrack, S. A. Flannery, Troy E. Metzger, Shozo Izui, Joshua M. Thurman
Publikováno v:
Genes and Immunity, Vol. 7, No 7 (2006) pp. 555-567
Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology. Associations between viral infections and the onset of SLE have been suggested, and recent studies have provided evidence that type I interferons (IFNalpha/beta) might p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861c38bc875c34fa163cebeda313413c
https://doi.org/10.1038/sj.gene.6364329
https://doi.org/10.1038/sj.gene.6364329
Autor:
Chenghui Huang, Susan Yung, Gongping Liang, Qianjin Lu, Rong Xiao, Tak Mao Chan, Ming Zhao, Yaping Li
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
Clinical and Developmental Immunology
Clinical and Developmental Immunology
The aberrant activity of CD4(+) T cells in patients with systemic lupus erythematosus (SLE) is associated with DNA hypomethylation of the regulatory regions in CD11a and CD70 genes. Our previous studies demonstrated that Gadd45a contributes to the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6eaff4ae16a1eb0f04d31df934380a
https://doaj.org/article/b31b71eb425743c796350ff07b7cb2d1
https://doaj.org/article/b31b71eb425743c796350ff07b7cb2d1
Publikováno v:
European Journal of Immunology, Vol. 26, No 2 (1996) pp. 307-314
The expression of a transgene encoding the I-E alpha chain prevents a lupus-like autoimmune syndrome in BXSB mice. However, it had not been elucidated whether the E alpha d transgene-mediated protective effect results from I-E expression or from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb1af1b9c1a3dc636a66b6a43a1b12e
https://doi.org/10.1002/eji.1830260206
https://doi.org/10.1002/eji.1830260206
Publikováno v:
Journal of Autoimmunity, Vol. 35, No 4 (2010) pp. 398-403
Journal of autoimmunity
Journal of autoimmunity
The endogenous retroviral envelope glycoprotein, gp70, implicated in murine lupus nephritis is secreted by hepatocytes, and its expression is largely regulated by the Sgp3 (serum gp70 production 3) locus derived from lupus-prone mice. Because of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f599313ec6e41d236966f31c9a98df8b
https://archive-ouverte.unige.ch/unige:20605
https://archive-ouverte.unige.ch/unige:20605
Autor:
Liliane Fossati-Jimack, Eri Amano, Hirofumi Amano, Thomas Moll, Shuichi Kikuchi, Shozo Izui, Marie-Laure Santiago-Raber, Brian L. Kotzin
Publikováno v:
Journal of Immunology, Vol. 176, No 5 (2006) pp. 3240-3247
The accelerated development of systemic lupus erythematosus (SLE) in BXSB male mice is associated with the presence of the Y-linked autoimmune acceleration (Yaa) mutation, which induces an age-dependent monocytosis. Using a cohort of C57BL/6 (B6) ×
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21d7ecd3f8b648f16ecef76779463d5
https://pubmed.ncbi.nlm.nih.gov/16493085
https://pubmed.ncbi.nlm.nih.gov/16493085
Autor:
Bernard J Morley, Joanna M. Rankin, Aileen McDermott, Mark Walport, Nicola J. Rogers, Shozo Izui, Liliane Fossati-Jimack, Vasuky Thiruudaian, S. Jane Rose, Michelle E. K. Haywood, Margarita Lewis, Joseph J. Boyle
Publikováno v:
Journal of Immunology, Vol. 173, No 7 (2004) pp. 4277-4285
To dissect the individual effects of the four non-MHC, autosomal loci (Bxs1 to Bxs4) that contribute to SLE susceptibility in BXSB mice, we generated congenic lines from chromosome 1 on a C57BL/10.YBXSB (B10.Yaa) background for the intervals (values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5e13d6da7b754cbf0a31ef64001090
https://pubmed.ncbi.nlm.nih.gov/15383556
https://pubmed.ncbi.nlm.nih.gov/15383556
Publikováno v:
Journal of Immunology, Vol. 172, No 7 (2004) pp. 4159-4166
The F1 hybrid of New Zealand Black (NZB) and New Zealand White (NZW) mice develop an autoimmune disease similar to human systemic lupus erythematosus. Because NZB and (NZB × NZW)F1 mice manifest expansions of marginal zone (MZ) B and B1a cells, it h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2042156165dd848ebb826ef5046dcf46
https://pubmed.ncbi.nlm.nih.gov/15034028
https://pubmed.ncbi.nlm.nih.gov/15034028
Publikováno v:
Immunology, Vol. 100, No 4 (2000) pp. 455-461
The self-antigen IgG2ab is poorly presented to a gamma2ab 435-451-reactive I-Ad-restricted T-cell hybridoma unless available in high concentrations or targeted to Fcgamma- or complement receptors. Environmental factors, probably the extent of microbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::31b634076aa8bd47ced188451ae1ae0d
https://europepmc.org/articles/PMC2327035/
https://europepmc.org/articles/PMC2327035/
Publikováno v:
Current Topics in Microbiology and Immunology, Vol. 246 (1999) pp. 275-280; discussion 281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f053d9663a2668f4bc3f62853781848c
https://archive-ouverte.unige.ch/unige:10914
https://archive-ouverte.unige.ch/unige:10914
Publikováno v:
Proceedings of the National Academy of Sciences, Vol. 96, No 14 (1999) pp. 8098-8103
Previous studies have suggested that MHC and non-MHC genes contribute to the development of autoimmune disease in F1hybrids of New Zealand black (NZB) and white (NZW) mice. We conducted a genome-wide screen of 148 female (NZB × NZW)F1× NZB backcros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc4e34167dcb038dfffc013a8acffcd
https://archive-ouverte.unige.ch/unige:11627
https://archive-ouverte.unige.ch/unige:11627