Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Luping Yuan"'
Autor:
Wentao Pan, Qiuyun Luo, Eric Liang, Mude Shi, Jian Sun, Huimin Shen, Zhenhai Lu, Lin Zhang, Xianglei Yan, Luping Yuan, Suna Zhou, Hanjie Yi, Yifan Zhai, Miao-zhen Qiu, Dajun Yang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Immune checkpoint inhibitors are approved for the treatment of various tumors, but the response rate is not satisfactory in certain malignancies. Inhibitor of apoptosis proteins (IAP) ubiquitin-E3 ligase activity is involved in th
Externí odkaz:
https://doaj.org/article/351b402f688449ceb4c6ca9f401e8dfc
Autor:
Luping Yuan, Jochen Springer, Sandra Palus, Silvia Busquets, Queralt Jové, Edson Alves de Lima Junior, Markus S. Anker, Stephan vonHaehling, Natalia Álvarez Ladrón, Oliver Millman, Annemijn Oosterlee, Agata Szymczyk, Francisco Javier López‐Soriano, Stefan D. Anker, Andrew J.S. Coats, Josep M. Argiles
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 653-660 (2023)
Abstract Background Beta‐blockers and selected stereoisomers of beta‐blockers, like bisoprolol and S‐pindolol (ACM‐001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of stereoisomers of o
Externí odkaz:
https://doaj.org/article/748d4538c7ce45089201c07ab020fbb6
Autor:
Hanjie Yi, Miao‐Zhen Qiu, Luping Yuan, Qiuyun Luo, Wentao Pan, Suna Zhou, Lin Zhang, Xianglei Yan, Da‐Jun Yang
Publikováno v:
Cancer Medicine, Vol 9, Iss 12, Pp 4197-4206 (2020)
Abstract Gastric carcinoma is the third major cause of cancer‐related death in China. Bcl‐2 and other BH3 family proteins are critically important in the process of apoptosis pathway, which may be a promising target. APG‐1252‐M1 specifically
Externí odkaz:
https://doaj.org/article/6d3d315277894e3ab1c21328cee0f491
Autor:
Hanjie Yi, Xianglei Yan, Qiuyun Luo, Luping Yuan, Baoxia Li, Wentao Pan, Lin Zhang, Haibo Chen, Jing Wang, Yubin Zhang, Yifan Zhai, Miao-Zhen Qiu, Da-Jun Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-10 (2018)
Abstract Background Gastric cancer is the leading cause of cancer related death worldwide. Radiation alone or combined with chemotherapy plays important role in locally advanced and metastatic gastric adenocarcinoma. MDM2–p53 interaction and downst
Externí odkaz:
https://doaj.org/article/741ca8ab6c9e4e2bb0e4bb81ca774357
Autor:
Luping Yuan, Jochen Springer, Sandra Palus, Silvia Busquets, Queralt Jové, Edson Alves de Lima Junior, Markus S. Anker, Stephan von Haehling, Natalia Álvarez Ladrón, Oliver Millman, Annemijn Oosterlee, Agata Szymczyk, Francisco Javier López‐Soriano, Stefan D. Anker, Andrew J.S. Coats, Josep M. Argiles
Publikováno v:
Journal of cachexia, sarcopenia and muscleReferences.
Beta-blockers and selected stereoisomers of beta-blockers, like bisoprolol and S-pindolol (ACM-001), have been shown to be effective in preclinical cancer cachexia models. Here, we tested the efficacy of stereoisomers of oxprenolol in two preclinical
Publikováno v:
Biochemical pharmacology. 205
The highly transmissible variants of SARS-CoV-2, the causative pathogen of the COVID-19 pandemic, bring new waves of infection worldwide. Identification of effective therapeutic drugs to combat the COVID-19 pandemic is an urgent global need. RNA-depe
Autor:
Xianglei Yan, Miao Zhen Qiu, Luping Yuan, Wentao Pan, Suna Zhou, Lin Zhang, Qiuyun Luo, Hanjie Yi, Dajun Yang
Publikováno v:
Cancer Medicine, Vol 9, Iss 12, Pp 4197-4206 (2020)
Cancer Medicine
Cancer Medicine
Gastric carcinoma is the third major cause of cancer‐related death in China. Bcl‐2 and other BH3 family proteins are critically important in the process of apoptosis pathway, which may be a promising target. APG‐1252‐M1 specifically connects
Autor:
Xianglei Yan, Hanjie Yi, Jian Sun, Lin Zhang, Luping Yuan, Dajun Yang, Zhen-yi Liu, Suna Zhou, Jing Wang, Wentao Pan, Haibo Chen, Guangfeng Wang, Miaozhen Qiu, Qiuyun Luo
Publikováno v:
Oncology Research
Despite therapeutic advances, the effective treatment for relapsed or refractory diffuse large B-cell lymphoma (DLBCL) remains a major clinical challenge. Evasion of apoptosis through upregulating antiapoptotic B-cell lymphoma-2 (BCL-2) family member
Autor:
Yuxin Zhang, Hanjie Yi, Baoxia Li, Miao Zhen Qiu, Jian Sun, Xianglei Yan, Luping Yuan, Wentao Pan, Lin Zhang, Qiuyun Luo, Dajun Yang
Publikováno v:
Biochemical Pharmacology. 154:127-135
Check point inhibitor anti-PD1 antibody produced some efficacy in Hepatocellular Carcinoma (HCC) patients previously treated with sorafenib. Unfortunately, HCC patients with hepatitis B virus (HBV) infection did not respond as well as uninfected pati
Minicircle-oriP-miR-31 as a Novel EBNA1-Specific miRNA Therapy Approach for Nasopharyngeal Carcinoma
Publikováno v:
Human Gene Therapy. 28:415-427
MicroRNAs (miRNAs) are important post-transcriptional regulators that control cancer development and progression. However, the application of miRNA therapy in cancer has been hampered by a lack of an efficient and targeted delivery system. In our pre