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Akademický článek

PCV15, a pneumococcal conjugate vaccine, for the prevention of invasive pneumococcal disease in infants and children

Autor: Timothy J Chapman, Liset Olarte, Ghassan Dbaibo, Avril Melissa Houston, Gretchen Tamms, Robert Lupinacci, Kristen Feemster, Ulrike K Buchwald, Natalie Banniettis

Publikováno v: Expert Review of Vaccines, Vol 23, Iss 1, Pp 137-147 (2024)

ABSTRACTIntroduction Streptococcus pneumoniae is a causative agent of pneumonia and acute otitis media (AOM), as well as invasive diseases such as meningitis and bacteremia. PCV15 (V114) is a new 15-valent pneumococcal conjugate vaccine (PCV) approve

Externí odkaz: https://doaj.org/article/8a4c9057ccf6425a95168278db4e417f

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Akademický článek

A phase 3, single-arm, open-label study to evaluate the safety, tolerability, and immunogenicity of a 15-valent pneumococcal conjugate vaccine, V114, in a 3+1 regimen in healthy infants in South Korea (PNEU-PED-KOR)

Autor: Alvino Maestri, Su Eun Park, Fiona Fernandes, Zhongyi “Lucy” Li, Yae-Jean Kim, Yun-Kyung Kim, Jin Lee, Ji Young Park, Dong Hyun Kim, GyongSeon Yang, Hyunjung Lim, Jin Oh Kim, Robert Lupinacci, Tina M. Sterling, Marissa Wilck, Alejandra Esteves-Jaramillo, Natalie Banniettis

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

ABSTRACTThere is an ongoing burden of pneumococcal disease in children despite the use of pneumococcal conjugate vaccines (PCVs). This phase 3, open-label, single-arm, multisite, descriptive study was designed to evaluate the safety and immunogenicit

Externí odkaz: https://doaj.org/article/bee75b52b4b44c919cf78d85f82b27ea

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Akademický článek

DNA CIRCULANTE TUMORAL NO LINFOMA DIFUSO DE GRANDES CÉLULAS B: SEU USO NA AVALIAÇÃO DE RESPOSTA AO TRATAMENTO, CORRELAÇÃO COM PET/CT E DADOS DE RADIÔMICA

Autor: C Cralcev, G Duffles, J Maues, F Lupinacci, EN Ferreira, F Niemann, MES Takahashi, CD Ramos, ML Chauffaille, I Lorand-Metze

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S247-S248 (2024)

Objetivos: Avaliar a correlação entre os níveis de DNA circulante tumoral (ctDNA) em pacientes com linfoma difuso de grandes células B (LDGCB), antes e ao longo do tratamento, com dados quantitativos obtidos do PET/CT e a resposta ao tratamento.

Externí odkaz: https://doaj.org/article/257bde8a6652419dac0f07543bd63c46

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Akademický článek

Randomized, open-label, phase 2 study of nivolumab plus ipilimumab or nivolumab monotherapy in patients with advanced or metastatic solid tumors of high tumor mutational burden

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)

Background Checkpoint inhibitor therapy has demonstrated overall survival benefit in multiple tumor types. Tumor mutational burden (TMB) is a predictive biomarker for response to immunotherapies. This study evaluated the efficacy of nivolumab+ipilimu

Externí odkaz: https://doaj.org/article/be397a2c9d104c41b010a59bc9500941

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Akademický článek

A Novel Prescription Digital Therapeutic Option for the Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease

Autor: Naim Alkhouri, Katherine Edwards, Mark Berman, Heather Finn, Rafael Escandon, Paul Lupinacci, Nicole Guthrie, Angie Coste, Jesus Topete, Mazen Noureddin

Publikováno v: Gastro Hep Advances, Vol 3, Iss 1, Pp 9-16 (2024)

Background and Aims: Metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis are pressing public health problems occurring alongside the rising prevalence of obesity and diabetes. This feasibility

Externí odkaz: https://doaj.org/article/39dc746a0cf24980b8c8816593edfdd4

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Report

Volume 78, 1 October 2014, Pages 56-64

Autor: Lupinacci, A., Kacher, J., Shapiro, A. A., Hosemann, P., Minor, A. M.

Publikováno v: Acta Materialia Volume 78, 1 October 2014, Pages 56-64

Characterizing plasticity mechanisms below the ductile-to-brittle transition temperature is traditionally difficult to accomplish in asystematic fashion. Here, we use a new experimental setup to perform in situ cryogenic mechanical testing of pure Sn

Externí odkaz: http://arxiv.org/abs/2104.00806

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Akademický článek

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Akademický článek

FROM LEFT TO RIGHT. PARA-AORTIC LYMPH NODES SAMPLING DURING PANCREATODUODENECTOMY FOR PANCREATIC CANCER

Autor: Gabrielle Stevenin, Clémence Guyard, Renato Micelli Lupinacci

Publikováno v: ABCD: Arquivos Brasileiros de Cirurgia Digestiva, Vol 36 (2023)

ABSTRACT BACKGROUND: Para-aortic lymph nodes involvement in pancreatic head cancer has been described as an independent adverse prognostic factor. To avoid futile pancreatic resection, we systematically perform para-aortic lymphadenectomy as a first

Externí odkaz: https://doaj.org/article/1288d07b9c2243d280f3e6d63fd645b4

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Akademický článek

DESENVOLVIMENTO DE TESTE DIAGNÓSTICO PARA LEUCEMIA LINFOBLÁSTICA AGUDA POR SEQUENCIAMENTO DE NOVA GERAÇÃO

Autor: FS Lupinacci, ARDS Fornari, M Eloi, NMA Pioli, JVM Malvezzi, FPS Santos, ADSB Perazzio, CS Rocha, ENE Ferreira, ML Chauffaille

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 45, Iss , Pp S244-S245 (2023)

Objetivos: Desenvolver e validar um teste genético para análise de mutações somáticas relacionadas a leucemia linfoblástica aguda (LLA) e assim dispor de uma abordagem molecular de investigação genética por meio de sequenciamento de nova ger

Externí odkaz: https://doaj.org/article/ad610ccc3b234a4eafba25debf24e265

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